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Author: Petar M. Mitrasinovic
Publisher: Bentham Science Publishers
Published: 2012-12-15
Total Pages: 4
ISBN-13:
DOWNLOAD EBOOKCurrent Bioinformatics, Volume 7, Number 4, 2012 ISSN: 1574-8936, eISSN: 2212-392X
Author: Gil Alterovitz
Publisher: John Wiley & Sons
Published: 2011-04-20
Total Pages: 306
ISBN-13: 1119995833
DOWNLOAD EBOOKThere is an increasing need throughout the biomedical sciences for a greater understanding of knowledge-based systems and their application to genomic and proteomic research. This book discusses knowledge-based and statistical approaches, along with applications in bioinformatics and systems biology. The text emphasizes the integration of different methods for analysing and interpreting biomedical data. This, in turn, can lead to breakthrough biomolecular discoveries, with applications in personalized medicine. Key Features: Explores the fundamentals and applications of knowledge-based and statistical approaches in bioinformatics and systems biology. Helps readers to interpret genomic, proteomic, and metabolomic data in understanding complex biological molecules and their interactions. Provides useful guidance on dealing with large datasets in knowledge bases, a common issue in bioinformatics. Written by leading international experts in this field. Students, researchers, and industry professionals with a background in biomedical sciences, mathematics, statistics, or computer science will benefit from this book. It will also be useful for readers worldwide who want to master the application of bioinformatics to real-world situations and understand biological problems that motivate algorithms.
Author: Tarun Weeramanthri
Publisher: Frontiers Media SA
Published: 2018-06-25
Total Pages: 149
ISBN-13: 2889455017
DOWNLOAD EBOOKPrecision Public Health is a new and rapidly evolving field, that examines the application of new technologies to public health policy and practice. It draws on a broad range of disciplines including genomics, spatial data, data linkage, epidemiology, health informatics, big data, predictive analytics and communications. The hope is that these new technologies will strengthen preventive health, improve access to health care, and reach disadvantaged populations in all areas of the world. But what are the downsides and what are the risks, and how can we ensure the benefits flow to those population groups most in need, rather than simply to those individuals who can afford to pay? This is the first collection of theoretical frameworks, analyses of empirical data, and case studies to be assembled on this topic, published to stimulate debate and promote collaborative work.
Author: National Research Council
Publisher: National Academies Press
Published: 2006-01-01
Total Pages: 469
ISBN-13: 030909612X
DOWNLOAD EBOOKAdvances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.
Author: Institute of Medicine
Publisher: National Academies Press
Published: 2012-09-13
Total Pages: 354
ISBN-13: 0309224187
DOWNLOAD EBOOKTechnologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.
Author: National Research Council
Publisher: National Academies Press
Published: 2003-07-19
Total Pages: 297
ISBN-13: 0309089123
DOWNLOAD EBOOKThe nature of biomedical research has been evolving in recent years. Technological advances that make it easier to study the vast complexity of biological systems have led to the initiation of projects with a larger scale and scope. In many cases, these large-scale analyses may be the most efficient and effective way to extract functional information from complex biological systems. Large-Scale Biomedical Science: Exploring Strategies for Research looks at the role of these new large-scale projects in the biomedical sciences. Though written by the National Academies' Cancer Policy Board, this book addresses implications of large-scale science extending far beyond cancer research. It also identifies obstacles to the implementation of these projects, and makes recommendations to improve the process. The ultimate goal of biomedical research is to advance knowledge and provide useful innovations to society. Determining the best and most efficient method for accomplishing that goal, however, is a continuing and evolving challenge. The recommendations presented in Large-Scale Biomedical Science are intended to facilitate a more open, inclusive, and accountable approach to large-scale biomedical research, which in turn will maximize progress in understanding and controlling human disease.
Author: Francisco Azuaje
Publisher: John Wiley & Sons
Published: 2011-08-24
Total Pages: 206
ISBN-13: 111996430X
DOWNLOAD EBOOKThis book is designed to introduce biologists, clinicians and computational researchers to fundamental data analysis principles, techniques and tools for supporting the discovery of biomarkers and the implementation of diagnostic/prognostic systems. The focus of the book is on how fundamental statistical and data mining approaches can support biomarker discovery and evaluation, emphasising applications based on different types of "omic" data. The book also discusses design factors, requirements and techniques for disease screening, diagnostic and prognostic applications. Readers are provided with the knowledge needed to assess the requirements, computational approaches and outputs in disease biomarker research. Commentaries from guest experts are also included, containing detailed discussions of methodologies and applications based on specific types of "omic" data, as well as their integration. Covers the main range of data sources currently used for biomarker discovery Covers the main range of data sources currently used for biomarker discovery Puts emphasis on concepts, design principles and methodologies that can be extended or tailored to more specific applications Offers principles and methods for assessing the bioinformatic/biostatistic limitations, strengths and challenges in biomarker discovery studies Discusses systems biology approaches and applications Includes expert chapter commentaries to further discuss relevance of techniques, summarize biological/clinical implications and provide alternative interpretations
Author: Viviana E. Ferraggine
Publisher: IGI Global
Published: 2009-01-01
Total Pages: 986
ISBN-13: 1605662437
DOWNLOAD EBOOK"This book provides a wide compendium of references to topics in the field of the databases systems and applications"--Provided by publisher.
Author: Evelyn J. S. Hovenga
Publisher: IOS Press
Published: 2010
Total Pages: 520
ISBN-13: 1607500922
DOWNLOAD EBOOKThis second, extensively revised and updated edition of Health Informatics: An Overview includes new topics which address contemporary issues and challenges and shift the focus on the health problem space towards a computer perspective.
Author: Paraskevas D. Tzanavaras
Publisher: Bentham Science Publishers
Published: 2010
Total Pages: 160
ISBN-13: 1608051900
DOWNLOAD EBOOK"Reviews in Pharmaceutical and Biomedical Analysis contains coverage and review of new trends and applications in all areas of pharmaceutical, biomedical and analytical chemistry. Authors have contributed review articles according to their expertise on var"
