Current Topics in Microbiology and Immunology
Current Topics in Microbiology and Immunology

Author: W. Henle

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 312

ISBN-13: 3642681204

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Several discoveries are noteworthy for allowing us to probe the recesses of the virus℗Ư infected cell and to search for cryptic viral genomes which might provide clues in our studies of cancer etiology or developmental biology. One of the most notable was the dis℗Ư covery of reverse transcriptase. This marked a momentous occasion in the history of molecular biology. Not only did it provide insight into the mechanism of persistence of retroviruses but it also provided us with an enzyme that could synthesize a DNA copy of any RNA. This DNA copy could then be used as a hybridization reagent to search for both complementary DNA and viral-specific RNA. Thus one could follow the course of any viral infection or probe in tumor cells for hidden viral genomes. Second, a great deal of credit must be given to the geneticists who isolated the various deletion mutants in the 'avian retrovirus system and thus provided us with the frrst means of isolating gene-spe℗Ư cific probes. Finally, the laboratories which have mapped the genome have provided us with the framework in which to ask very specific questions with our gene-specific probes. Recently, numerous excellent reviews concerning various aspects of the retroviruses have appeared. In this review I shall not even attempt to present a comprehensive review of retroviruses.

Epidemics and the Modern World
Epidemics and the Modern World

Author: Mitchell L. Hammond

Publisher: University of Toronto Press

Published: 2020-01-16

Total Pages: 536

ISBN-13: 1487593732

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Epidemics and the Modern World uses "biographies" of epidemics such as plague, tuberculosis, and HIV/AIDS to explore the impact of diseases on society from the fourteenth century to the twenty-first century.

Function and Specificity of γ/δ T Cells
Function and Specificity of γ/δ T Cells

Author: Klaus Pfeffer

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 277

ISBN-13: 3642764924

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Our current understanding of a/~ T cell receptor (TCR) ex pressing T cells advanced from function and specificity to the molecular organization ofthe TCR.We now know that the TCR a and ~ chains together express specificity for (antigenic) peptides presented by the "responder" M H C allele, thus explain ing the phenomenon of MHC restriction at a molecular level. Surprisingly even though our perception of the molecular organization of the y5 TCR is well advanced, current knowledge of function and specificity of the y5 T cell subset is poor. There fore it appeared rather timely to bring together scientists pioneering research on y5 T cells forthe International Workshop on Function and Specificity ofy5 Tcells,held October11-14, 1990 at Schloss Elmau/Bavaria, FRG. Besides offering a scientific forum for open discussions, it was also hoped that such a workshop would be seminal for collaborative interactions and personal relationships among scientists "addicted" to y 15 T cells.

The Intersection of Food and Public Health
The Intersection of Food and Public Health

Author: A. Bryce Hoflund

Publisher: CRC Press

Published: 2017-09-13

Total Pages: 351

ISBN-13: 1351649132

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Presently, ideas about food are in flux from a variety of sources. Examples of this evolution include recognizing the importance of food on health by public health and medical professionals; changing consumer desires around the production methods and components of their food; a greater focus on injustices within the national food system; evolving knowledge of how the food system impacts the environment; and, shifting economic and technological realities that underpin where and how food is produced, distributed and sold. These shifting ideas about food exist in contrast to the narrative of the highly functioning, industrialized, global food system that emerged in the second half of the 20th century. This edited volume fills a void by presenting a comprehensive and engaging coverage of the key issues at the intersection of public health, policy, and food. The Intersection of Food and Public Health is comprised of research that examines current problems in food studies and how various stakeholders are attempting to address problems in unique ways. The book will be of interest to undergraduate and graduate students in a variety of disciplines, including public administration, public policy, public health, economics, political science, nutrition, dietetics, and food studies.