Meeting Critical Laboratory Needs for Animal Agriculture

Meeting Critical Laboratory Needs for Animal Agriculture

Author: National Research Council

Publisher: National Academies Press

Published: 2012-10-28

Total Pages: 144

ISBN-13: 0309261295

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Outbreaks of animal disease can have catastrophic repercussions for animal agriculture, the food supply, and public health. Rapid detection, diagnosis and response, as well as development of new vaccines, are central to mitigating the impact of disease outbreaks. The proposed National Bio- and Agro-Defense Facility (NBAF) is a next-generation laboratory for animal disease diagnostics, training, and research that would provide core critical components for defense against foreign animal and zoonotic disease threats. But it will be a major investment with estimated construction costs of $1.14 billion, as currently designed. Meeting Critical Laboratory Needs for Animal Agriculture: Examination of Three Optionsdiscusses the laboratory infrastructure needed to effectively address the threat posed by animal and zoonotic diseases and analyzes three options for creating this infrastructure: building NBAF as currently designed, building a scaled-back version of the NBAF, or maintaining current research capabilities at Plum Island Animal Disease Center while leveraging biosafety level-4 large animal capabilities at foreign laboratories.


Science

Science

Author:

Publisher:

Published: 2009

Total Pages: 840

ISBN-13:

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Vols. for 1911-13 contain the Proceedings of the Helminothological Society of Washington, ISSN 0018-0120, 1st-15th meeting.


Biological Espionage

Biological Espionage

Author: Alexander Kouzminov

Publisher: Greenhill Books

Published: 2005

Total Pages: 0

ISBN-13: 9781853676468

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In the wake of 9/11 the threat of biological terrorism and sabotage has been thrust to the forefront of public consciousness. However, this is far from being a new phenomenon. From World War II onwards, the Cold War powers devoted considerable resources to developing what became known in the military as µbugs and gas'. This groundbreaking study lifts the lid on the top-secret Department 12 of Directorate S (Special Operations) v the elite inner core of the KGB First Chief Directorate and its successor, the Russian Foreign Intelligence Service. During the 1980s and early 1990s the department encouraged biological espionage, the planning and preparation of biological terrorism and acts of sabotage. Their work was carried out primarily through µIllegals' v intelligence operatives who were secretly deployed to the West and covertly operated there, masquerading as citizens of Western countries under assumed names and cover stories. One of its top operatives, Alexander Kouzminov, has decided to break his silence and reveal in depth for the first time the department's tasks, plans and tactics. More disturbingly, he explores what others in the West and the developing world are and could be capable of. In this remarkable book we learn the secrets of the USSR's elite intelligence operatives v secrets which could prove vital in maintaining international security in today's uncertain political climate.


A Funny Thing Happened on the Way to Stockholm

A Funny Thing Happened on the Way to Stockholm

Author: Robert Lefkowitz

Publisher: Simon and Schuster

Published: 2021-02-02

Total Pages: 304

ISBN-13: 1643136399

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The rollicking memoir from the cardiologist turned legendary scientist and winner of the Nobel Prize that revels in the joy of science and discovery. Like Richard Feynman in the field of physics, Dr. Robert Lefkowitz is also known for being a larger-than-life character: a not-immodest, often self-deprecating, always entertaining raconteur. Indeed, when he received the Nobel Prize, the press corps in Sweden covered him intensively, describing him as “the happiest Laureate.” In addition to his time as a physician, from being a "yellow beret" in the public health corps with Dr. Anthony Fauci to his time as a cardiologist, and his extraordinary transition to biochemistry, which would lead to his Nobel Prize win, Dr. Lefkowitz has ignited passion and curiosity as a fabled mentor and teacher. But it's all in a days work, as Lefkowitz reveals in A Funny Thing Happened on the Way to Stockholm, which is filled to the brim with anecdotes and energy, and gives us a glimpse into the life of one of today's leading scientists.


Practical Flow Cytometry

Practical Flow Cytometry

Author: Howard M. Shapiro

Publisher: John Wiley & Sons

Published: 2005-02-25

Total Pages: 736

ISBN-13: 0471434035

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From the reviews of the 3rd Edition... "The standard reference for anyone interested in understandingflow cytometry technology." American Journal of Clinical Oncology "...one of the most valuable of its genre and...addressed to awide audience?written in such an attractive way, being bothinformative and stimulating." Trends in Cell Biology This reference explains the science and discusses the vastbiomedical applications of quantitative analytical cytology usinglaser-activated detection and cell sorting. Now in its fourthedition, this text has been expanded to provide full coverage ofthe broad spectrum of applications in molecular biology andbiotechnology today. New to this edition are chapters on automatedanalysis of array technologies, compensation, high-speed sorting,reporter molecules, and multiplex and apoptosis assays, along withfully updated and revised references and a list of suppliers.


TRAIL, Fas Ligand, TNF and TLR3 in Cancer

TRAIL, Fas Ligand, TNF and TLR3 in Cancer

Author: Olivier Micheau

Publisher: Springer

Published: 2017-07-03

Total Pages: 320

ISBN-13: 3319568051

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This volume provides the current understanding of death receptor's/TLR3 signaling regulation in cancer. Death receptors, including TRAIL-R1, TRAIL-R2, Fas and TNF-RI, owing to their ability to trigger apoptosis and to contribute to the elimination of cancer cells by the immune system have been considered, to variable extent, as important therapeutic targets for cancer therapy. But an increasing body of evidence suggests that some of these receptors may also contribute to tumorigenesis, or that new players such as TLR3 may be targeted for cancer therapy due to their ability to behave like death receptors.