Conceptual Breakthroughs in The Evolutionary Biology of Aging
Conceptual Breakthroughs in The Evolutionary Biology of Aging

Author: Kenneth R. Arnold

Publisher: Academic Press

Published: 2023-07-10

Total Pages: 310

ISBN-13: 0128215461

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Conceptual Breakthroughs in the Evolutionary Biology of Aging continues the innovative Conceptual Breakthroughs series by providing a comprehensive outline of the major breakthroughs that built the evolutionary biology of aging as a leading scientific field. Following the evolutionary study of aging from its humble origins to the present, the book's chapters treat the field's breakthroughs one at a time. Users will find a concise and accessible analysis of the science of aging viewed through an evolutionary lens. Building upon widely-cited studies conducted by author Michael Rose, this book covers 30 subsequent years of growth and development within the field.The book highlights key publications for those who are not experts in the field, providing an important resource for researchers. Given the prevailing interest in changing the aging process dramatically, it is a powerful tool for readers who have a vested interest in understanding its causes and future control measures. - Reviews cell-molecular theories of aging in the light of evolutionary biology - Offers an evolutionary analysis of prospects for mitigating aging not commonly discussed within private and public sectors - Provides readers with a radically different perspective on contemporary biological gerontology, specifically through the lens of evolutionary biology

Conceptual Breakthroughs in Evolutionary Ecology
Conceptual Breakthroughs in Evolutionary Ecology

Author: Laurence Mueller

Publisher: Academic Press

Published: 2019-11-19

Total Pages: 206

ISBN-13: 0128160144

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Although biologists recognize evolutionary ecology by name, many only have a limited understanding of its conceptual roots and historical development. Conceptual Breakthroughs in Evolutionary Ecology fills that knowledge gap in a thought-provoking and readable format. Written by a world-renowned evolutionary ecologist, this book embodies a unique blend of expertise in combining theory and experiment, population genetics and ecology. Following an easily-accessible structure, this book encapsulates and chronologizes the history behind evolutionary ecology. It also focuses on the integration of age-structure and density-dependent selection into an understanding of life-history evolution. - Covers over 60 seminal breakthroughs and paradigm shifts in the field of evolutionary biology and ecology - Modular format permits ready access to each described subject - Historical overview of a field whose concepts are central to all of biology and relevant to a broad audience of biologists, science historians, and philosophers of science

Conceptual Breakthroughs in Evolutionary Genetics
Conceptual Breakthroughs in Evolutionary Genetics

Author: John C. Avise

Publisher: Academic Press

Published: 2014-01-18

Total Pages: 185

ISBN-13: 0124202373

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Conceptual Breakthroughs in Evolutionary Genetics is a pithy, lively book occupying a special niche—the conceptual history of evolutionary genetics— not inhabited by any other available treatment. Written by a world-leading authority in evolutionary genetics, this work encapsulates and ranks 70 of the most significant paradigm shifts in evolutionary biology and genetics during the century-and-a-half since Darwin and Mendel. The science of evolutionary genetics is central to all of biology, but many students and other practitioners have little knowledge of its historical roots and conceptual developments. This book fills that knowledge gap in a thought-provoking and readable format. This fascinating chronological journey along the many conceptual pathways to our modern understanding of evolutionary and genetic principles is a wonderful springboard for discussions in undergraduate or graduate seminars in evolutionary biology and genetics. But more than that, anyone interested in the history and philosophy of science will find much of value between its covers. - Provides a relative ranking of 70 seminal breakthroughs and paradigm shifts in the field of evolutionary biology and genetics - Modular format permits ready access to each described subject - Historical overview of a field whose concepts are central to all of biology and relevant to a broad audience of biologists, science historians, and philosophers of science - Extensively cross-referenced with a guide to landmark papers and books for each topic

Big Questions in Ecology and Evolution
Big Questions in Ecology and Evolution

Author: Thomas N. Sherratt

Publisher: Oxford University Press

Published: 2009-02-19

Total Pages: 312

ISBN-13: 0199548609

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This book provides an introduction to a range of fundamental questions that have taxed evolutionary biologists and ecologists for decades. All of the questions posed have at least a partial solution, all have seen exciting breakthroughs in recent years, yet many of the explanations have been hotly debated.

Evolutionary Biology of Aging
Evolutionary Biology of Aging

Author: Michael R. Rose

Publisher: Oxford University Press

Published: 1994-10-27

Total Pages: 236

ISBN-13: 0198022727

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This unique book looks at the biology of aging from a fundamentally new perspective, one based on evolutionary theory rather than traditional concepts which emphasize molecular and cellular processes. The basis for this approach lies in the fact that natural selection, as a powerful determining force, tends to decline in importance with age. Many of the characteristics we associate with aging, the author argues, are more the result of this decline than any mechanical imperative contained within organic structures. This theory in turn yields the most fruitful avenues for seeking answers to the problem of aging, and should be recognized as the intellectual core of gerontology and the foundation for future research. The author ably surveys the vast literature on aging, presenting mathematical, experimental, and comparative findings to illustrate and support the central thesis. The result is the first complete synthesis of this vital field. Evolutionary biologists, gerontologists, and all those concerned with the science of aging will find it a stimulating, strongly argued account.

The Logic of Chance
The Logic of Chance

Author: Eugene V. Koonin

Publisher: FT Press

Published: 2011-06-23

Total Pages: 530

ISBN-13: 013262317X

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The Logic of Chance offers a reappraisal and a new synthesis of theories, concepts, and hypotheses on the key aspects of the evolution of life on earth in light of comparative genomics and systems biology. The author presents many specific examples from systems and comparative genomic analysis to begin to build a new, much more detailed, complex, and realistic picture of evolution. The book examines a broad range of topics in evolutionary biology including the inadequacy of natural selection and adaptation as the only or even the main mode of evolution; the key role of horizontal gene transfer in evolution and the consequent overhaul of the Tree of Life concept; the central, underappreciated evolutionary importance of viruses; the origin of eukaryotes as a result of endosymbiosis; the concomitant origin of cells and viruses on the primordial earth; universal dependences between genomic and molecular-phenomic variables; and the evolving landscape of constraints that shape the evolution of genomes and molecular phenomes. "Koonin's account of viral and pre-eukaryotic evolution is undoubtedly up-to-date. His "mega views" of evolution (given what was said above) and his cosmological musings, on the other hand, are interesting reading." Summing Up: Recommended Reprinted with permission from CHOICE, copyright by the American Library Association.

The Princeton Guide to Evolution
The Princeton Guide to Evolution

Author: David A. Baum

Publisher: Princeton University Press

Published: 2017-03-21

Total Pages: 886

ISBN-13: 069117587X

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The essential one-volume reference to evolution The Princeton Guide to Evolution is a comprehensive, concise, and authoritative reference to the major subjects and key concepts in evolutionary biology, from genes to mass extinctions. Edited by a distinguished team of evolutionary biologists, with contributions from leading researchers, the guide contains some 100 clear, accurate, and up-to-date articles on the most important topics in seven major areas: phylogenetics and the history of life; selection and adaptation; evolutionary processes; genes, genomes, and phenotypes; speciation and macroevolution; evolution of behavior, society, and humans; and evolution and modern society. Complete with more than 100 illustrations (including eight pages in color), glossaries of key terms, suggestions for further reading on each topic, and an index, this is an essential volume for undergraduate and graduate students, scientists in related fields, and anyone else with a serious interest in evolution. Explains key topics in some 100 concise and authoritative articles written by a team of leading evolutionary biologists Contains more than 100 illustrations, including eight pages in color Each article includes an outline, glossary, bibliography, and cross-references Covers phylogenetics and the history of life; selection and adaptation; evolutionary processes; genes, genomes, and phenotypes; speciation and macroevolution; evolution of behavior, society, and humans; and evolution and modern society

Advances in Geroscience
Advances in Geroscience

Author: Felipe Sierra

Publisher: Springer

Published: 2015-11-10

Total Pages: 637

ISBN-13: 3319232460

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This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or ‘healthspan.’ The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer’s diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.

How and why We Age
How and why We Age

Author: Leonard Hayflick

Publisher:

Published: 1996

Total Pages: 0

ISBN-13: 9780345401557

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"How long can humans live? Is immortality possible? Just what is the aging process? The aging and inevitable death of the human body have inspired more myths and outrageous quackery than anything else subject to scientific inquiry. . . . Now comes a most fascinating book, insightful and scholarly, to provide what answers have emerged so far." --San Francisco Chronicle Here, at last, preeminent cell biologist Leonard Hayflick presents the truth about human aging. Based on more than thirty years of pioneering research in the field, How and Why We Age explores not only how our major biological systems change as we grow older, but also examines the intangible alterations in our modes of thinking and feeling, our moods and sexual desires, our personality traits and our memories. With the immediacy of the latest scientific discoveries, Dr. Hayflick explains how aging affects every part of the body, and dispels many of the most persistent aging myths, to show that: * Hearts do not naturally get weaker with age. * Regular exercise and a low-fat diet won't slow aging. * Curing cancer would only add two years to the average sixty-five-year-old American life. Curing heart disease, however would add fourteen years. * Only five percent of people over the age of sixty-five are in nursing homes * No human has lived--or probably can live--past 120 years. Gracefully written, clearly organized, and packed with essential facts and statistics, How and Why We Age is a landmark study of the aging process for readers of all ages. "Written in clear, nontechnical language, it is an excellent introduction to the scientific and demographic literature on this multifacetedsubject." --Nature