Catalysis by TRNA-guanine Transglycosylase from Escherichia Coli
Author: Jeffrey David Kittendorf
Publisher:
Published: 2004
Total Pages: 378
ISBN-13:
DOWNLOAD EBOOKRead and Download eBook Full
Author: Jeffrey David Kittendorf
Publisher:
Published: 2004
Total Pages: 378
ISBN-13:
DOWNLOAD EBOOKAuthor: Gerhard Heldmaier
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 292
ISBN-13: 3642560962
DOWNLOAD EBOOKAnimals and plants live in changing environmental conditions which require adaptation in order to cope with this. Some of these environmental changes serve as signals which have to be "sensed" and interpreted correctly by the organisms to initiate the adaptation. This signal processing is based on biochemical, molecular and neuronal processes which are discussed in this book. All examples given underline that continuous adjustment of physiological functions is an essential requirement for life and survival in complex changing environments.
Author: Peter Grinspoon
Publisher: Hachette Books
Published: 2016-02-16
Total Pages: 239
ISBN-13: 031638268X
DOWNLOAD EBOOKFree Refills is the harrowing tale of a Harvard-trained medical doctor run horribly amok through his addiction to prescription medication, and his recovery. Dr. Peter Grinspoon seemed to be a total success: a Harvard-educated M.D. with a thriving practice; married with two great kids and a gorgeous wife; a pillar of his community. But lurking beneath the thin veneer of having it all was an addict fueled on a daily boatload of prescription meds. When the police finally came calling--after a tip from a sharp-eyed pharmacist--Grinspoon's house of cards came tumbling down fast. His professional ego turned out to be an impediment to getting clean as he cycled through recovery to relapse, his reputation, family life, and lifestyle in ruins. What finally moves him to recover and reclaim life--including working with other physicians who themselves are addicts--makes for inspiring reading.
Author: Isabelle Guyon
Publisher: Springer
Published: 2008-11-16
Total Pages: 765
ISBN-13: 3540354883
DOWNLOAD EBOOKThis book is both a reference for engineers and scientists and a teaching resource, featuring tutorial chapters and research papers on feature extraction. Until now there has been insufficient consideration of feature selection algorithms, no unified presentation of leading methods, and no systematic comparisons.
Author: Chris Margules
Publisher: Cambridge University Press
Published: 2007-09-13
Total Pages: 278
ISBN-13: 9780521878753
DOWNLOAD EBOOKSystematic Conservation Planning provides a clear, comprehensive guide to the process of deriving a conservation area network for regions, which will best represent the biodiversity of regions in the most cost-effective way. The measurement of biodiversity, design of field sampling strategies, alongside different data treatment methods are detailed helping to provide a conceptual framework for identifying conservation area networks, underpinned by the concept of complementarity. Setting conservation targets and then multi-criteria analyses, using complementarity but bringing in other criteria reflecting competing uses of land or water, to show how conservation area networks can achieve conservation targets in ways that also allow for the production of food, fiber and shelter are also discussed. Providing a clear procedure for identifying conservation priority areas underpinned by cutting edge science, this book will be of interest to graduate students, academics, planners and decision makers dealing with natural resource use and exploitation, alongside conservation NGOs.
Author: Tandy Warnow
Publisher: Springer
Published: 2019-04-08
Total Pages: 426
ISBN-13: 3030108376
DOWNLOAD EBOOKThis volume presents a compelling collection of state-of-the-art work in algorithmic computational biology, honoring the legacy of Professor Bernard M.E. Moret in this field. Reflecting the wide-ranging influences of Prof. Moret’s research, the coverage encompasses such areas as phylogenetic tree and network estimation, genome rearrangements, cancer phylogeny, species trees, divide-and-conquer strategies, and integer linear programming. Each self-contained chapter provides an introduction to a cutting-edge problem of particular computational and mathematical interest. Topics and features: addresses the challenges in developing accurate and efficient software for the NP-hard maximum likelihood phylogeny estimation problem; describes the inference of species trees, covering strategies to scale phylogeny estimation methods to large datasets, and the construction of taxonomic supertrees; discusses the inference of ultrametric distances from additive distance matrices, and the inference of ancestral genomes under genome rearrangement events; reviews different techniques for inferring evolutionary histories in cancer, from the use of chromosomal rearrangements to tumor phylogenetics approaches; examines problems in phylogenetic networks, including questions relating to discrete mathematics, and issues of statistical estimation; highlights how evolution can provide a framework within which to understand comparative and functional genomics; provides an introduction to Integer Linear Programming and its use in computational biology, including its use for solving the Traveling Salesman Problem. Offering an invaluable source of insights for computer scientists, applied mathematicians, and statisticians, this illuminating volume will also prove useful for graduate courses on computational biology and bioinformatics.
Author: Jay Fulcher
Publisher: John Wiley & Sons
Published: 2021-06-22
Total Pages: 61
ISBN-13: 1119785235
DOWNLOAD EBOOKHow the Best Companies are Skipping HR and Winning the Future of Work with People Ops People Operations: Automate HR, Design a Great Employee Experience, and Unleash Your Workforce explains how leaders at small- and medium-sized businesses can stop spending time on HR administration—"paperwork"—and start focusing on the "peoplework" that truly fuels employee growth and productivity. Authors Jay Fulcher, Kevin Marasco, Tracy Cote of Zenefits, the leading people operations platform, provide readers with a playbook for creating a massive competitive advantage by eliminating antiquated approaches to HR. The book takes a look at how work has changed and what companies need to do about it, and the new approach they must take to processes, systems, and best practices. You'll learn how to eliminate busywork and hassle, and how to use that newfound time and capital to empower your biggest asset: your people. You'll receive the end-to-end guide to: Digitizing legacy HR functions Using robots for the busywork you hate Employing software to design and improve your employee experience Assembling and empowering your "people team" Utilizing the included plans and templates to guide each stage of your business transformation Perfect for managers, leaders, small business owners, and executives, People Operations is perfect for anyone who wants to optimize HR, maximize their workforce investment, support their employees, and modernize their business.
Author: Kate Curtis
Publisher: Elsevier Health Sciences
Published: 2015-10-16
Total Pages: 1474
ISBN-13: 0729584593
DOWNLOAD EBOOK- Highlighted skills - cross references to the Clinical Skills chapter throughout text - Over 30 new case studies - Patient journey from pre-hospital and emergency-specific case studies - Critical thinking questions at the end of chapters - Chapter 35 Obstetric emergencies now includes 'Supporting a normal birth'.
Author: Robert O. Williams III
Publisher: Springer Science & Business Media
Published: 2011-12-04
Total Pages: 656
ISBN-13: 1461411440
DOWNLOAD EBOOKThis volume is intended to provide the reader with a breadth of understanding regarding the many challenges faced with the formulation of poorly water-soluble drugs as well as in-depth knowledge in the critical areas of development with these compounds. Further, this book is designed to provide practical guidance for overcoming formulation challenges toward the end goal of improving drug therapies with poorly water-soluble drugs. Enhancing solubility via formulation intervention is a unique opportunity in which formulation scientists can enable drug therapies by creating viable medicines from seemingly undeliverable molecules. With the ever increasing number of poorly water-soluble compounds entering development, the role of the formulation scientist is growing in importance. Also, knowledge of the advanced analytical, formulation, and process technologies as well as specific regulatory considerations related to the formulation of these compounds is increasing in value. Ideally, this book will serve as a useful tool in the education of current and future generations of scientists, and in this context contribute toward providing patients with new and better medicines.
Author: Kenny B. Lipkowitz
Publisher: Wiley-VCH
Published: 2002-10-23
Total Pages: 384
ISBN-13: 9780471215769
DOWNLOAD EBOOKThis volume, like those prior to it, features chapters by experts in various fields of computational chemistry. Topics covered in Volume 18 include molecular modeling, computer-assisted molecular design (camd), quantum chemistry, molecular mechanics and dynamics, and quantitative structure-activity relationships (qsar).