Reliable and metrologically comparable results of quantitative analytical methods are essential to assure that decisions taken on their basis have meaning and context. Problems with combining measurement results, calculating their uncertainties and establishing metrological traceability can prove complicated and ambiguous for measurement scientists. Combining and Reporting Analytical Results discusses in detail the problems faced by scientists, and presents a variety of approaches across biological, chemical and environmental sciences to resolving these types of issues. Topics include: validated methods of analysis; application of internal quality control procedures; participation in proficiency testing schemes; metrological traceability of measurement results and associated uncertainties, as well as some quality system issues and formal accreditation. Written by leading experts, and with worked examples and illustrations throughout, this invaluable reference source is ideal for analysts from various scientific fields.
The environment for obtaining information and providing statistical data for policy makers and the public has changed significantly in the past decade, raising questions about the fundamental survey paradigm that underlies federal statistics. New data sources provide opportunities to develop a new paradigm that can improve timeliness, geographic or subpopulation detail, and statistical efficiency. It also has the potential to reduce the costs of producing federal statistics. The panel's first report described federal statistical agencies' current paradigm, which relies heavily on sample surveys for producing national statistics, and challenges agencies are facing; the legal frameworks and mechanisms for protecting the privacy and confidentiality of statistical data and for providing researchers access to data, and challenges to those frameworks and mechanisms; and statistical agencies access to alternative sources of data. The panel recommended a new approach for federal statistical programs that would combine diverse data sources from government and private sector sources and the creation of a new entity that would provide the foundational elements needed for this new approach, including legal authority to access data and protect privacy. This second of the panel's two reports builds on the analysis, conclusions, and recommendations in the first one. This report assesses alternative methods for implementing a new approach that would combine diverse data sources from government and private sector sources, including describing statistical models for combining data from multiple sources; examining statistical and computer science approaches that foster privacy protections; evaluating frameworks for assessing the quality and utility of alternative data sources; and various models for implementing the recommended new entity. Together, the two reports offer ideas and recommendations to help federal statistical agencies examine and evaluate data from alternative sources and then combine them as appropriate to provide the country with more timely, actionable, and useful information for policy makers, businesses, and individuals.
The growing interest in using combination drugs to treat various complex diseases has spawned the development of many novel statistical methodologies. The theoretical development, coupled with advances in statistical computing, makes it possible to apply these emerging statistical methods in in vitro and in vivo drug combination assessments. Howeve
This book provide a comprehensive set of modeling methods for data and uncertainty analysis, taking readers beyond mainstream methods and focusing on techniques with a broad range of real-world applications. The book will be useful as a textbook for graduate students, or as a training manual in the fields of calibration and testing. The work may also serve as a reference for metrologists, mathematicians, statisticians, software engineers, chemists, and other practitioners with a general interest in measurement science.
A Practical Tool for Learning New Methods Quality assurance and measurement uncertainty in analytical laboratories has become increasingly important. To meet increased scrutiny and keep up with new methods, practitioners very often have to rely on self-study. A practical textbook for students and a self-study tool for analytical laboratory employees, Quality Assurance and Quality Control in the Analytical Chemical Laboratory: A Practical Approach defines the tools used in QA/QC, especially the application of statistical tools during analytical data treatment. Unified Coverage of QA in Analytical Chemistry Clearly written and logically organized, this book delineates the concepts of practical QA/QC, taking a generic approach that can be applied to any field of analysis. Using an approach grounded in hands-on experience, the book begins with the theory behind quality control systems and then moves on to discuss examples of tools such as validation parameter measurements, the use of statistical tests, counting the margin of error, and estimating uncertainty. The authors draw on their experience in uncertainty estimation, traceability, reference materials, statistics, proficiency tests, and method validation to provide practical guidance on each step of the process. Extended Coverage of QC/QA in Analytical and Testing Laboratories Presenting guidance on all aspects of QA and measurement results, the book covers QC/QA in a more complex and extended manner than other books on this topic. This range of coverage supplies an integrated view on measures like the use of reference materials and method validation. With worked-out examples and Excel spreadsheets that users can use to try the concepts themselves, the book provides not only know-what but know-how.
Over 19,000 total pages ... Public Domain U.S. Government published manual: Numerous illustrations and matrices. Published in the 1990s and after 2000. TITLES and CONTENTS: ELECTRICAL SCIENCES - Contains the following manuals: Electrical Science, Vol 1 - Electrical Science, Vol 2 - Electrical Science, Vol 3 - Electrical Science, Vol 4 - Thermodynamics, Heat Transfer, And Fluid Flow, Vol 1 - Thermodynamics, Heat Transfer, And Fluid Flow, Vol 2 - Thermodynamics, Heat Transfer, And Fluid Flow, Vol 3 - Instrumentation And Control, Vol 1 - Instrumentation And Control, Vol 2 Mathematics, Vol 1 - Mathematics, Vol 2 - Chemistry, Vol 1 - Chemistry, Vol 2 - Engineering Symbology, Prints, And Drawings, Vol 1 - Engineering Symbology, Prints, And Drawings, Vol 2 - Material Science, Vol 1 - Material Science, Vol 2 - Mechanical Science, Vol 1 - Mechanical Science, Vol 2 - Nuclear Physics And Reactor Theory, Vol 1 - Nuclear Physics And Reactor Theory, Vol 2. CLASSICAL PHYSICS - The Classical Physics Fundamentals includes information on the units used to measure physical properties; vectors, and how they are used to show the net effect of various forces; Newton's Laws of motion, and how to use these laws in force and motion applications; and the concepts of energy, work, and power, and how to measure and calculate the energy involved in various applications. * Scalar And Vector Quantities * Vector Identification * Vectors: Resultants And Components * Graphic Method Of Vector Addition * Component Addition Method * Analytical Method Of Vector Addition * Newton's Laws Of Motion * Momentum Principles * Force And Weight * Free-Body Diagrams * Force Equilibrium * Types Of Force * Energy And Work * Law Of Conservation Of Energy * Power – ELECTRICAL SCIENCE: The Electrical Science Fundamentals Handbook includes information on alternating current (AC) and direct current (DC) theory, circuits, motors, and generators; AC power and reactive components; batteries; AC and DC voltage regulators; transformers; and electrical test instruments and measuring devices. * Atom And Its Forces * Electrical Terminology * Units Of Electrical Measurement * Methods Of Producing Voltage (Electricity) * Magnetism * Magnetic Circuits * Electrical Symbols * DC Sources * DC Circuit Terminology * Basic DC Circuit Calculations * Voltage Polarity And Current Direction * Kirchhoff's Laws * DC Circuit Analysis * DC Circuit Faults * Inductance * Capacitance * Battery Terminology * Battery Theory * Battery Operations * Types Of Batteries * Battery Hazards * DC Equipment Terminology * DC Equipment Construction * DC Generator Theory * DC Generator Construction * DC Motor Theory * Types Of DC Motors * DC Motor Operation * AC Generation * AC Generation Analysis * Inductance * Capacitance * Impedance * Resonance * Power Triangle * Three-Phase Circuits * AC Generator Components * AC Generator Theory * AC Generator Operation * Voltage Regulators * AC Motor Theory * AC Motor Types * Transformer Theory * Transformer Types * Meter Movements * Voltmeters * Ammeters * Ohm Meters * Wattmeters * Other Electrical Measuring Devices * Test Equipment * System Components And Protection Devices * Circuit Breakers * Motor Controllers * Wiring Schemes And Grounding THERMODYNAMICS, HEAT TRANSFER AND FLUID FUNDAMENTALS. The Thermodynamics, Heat Transfer, and Fluid Flow Fundamentals Handbook includes information on thermodynamics and the properties of fluids; the three modes of heat transfer - conduction, convection, and radiation; and fluid flow, and the energy relationships in fluid systems. * Thermodynamic Properties * Temperature And Pressure Measurements * Energy, Work, And Heat * Thermodynamic Systems And Processes * Change Of Phase * Property Diagrams And Steam Tables * First Law Of Thermodynamics * Second Law Of Thermodynamics * Compression Processes * Heat Transfer Terminology * Conduction Heat Transfer * Convection Heat Transfer * Radiant Heat Transfer * Heat Exchangers * Boiling Heat Transfer * Heat Generation * Decay Heat * Continuity Equation * Laminar And Turbulent Flow * Bernoulli's Equation * Head Loss * Natural Circulation * Two-Phase Fluid Flow * Centrifugal Pumps INSTRUMENTATION AND CONTROL. The Instrumentation and Control Fundamentals Handbook includes information on temperature, pressure, flow, and level detection systems; position indication systems; process control systems; and radiation detection principles. * Resistance Temperature Detectors (Rtds) * Thermocouples * Functional Uses Of Temperature Detectors * Temperature Detection Circuitry * Pressure Detectors * Pressure Detector Functional Uses * Pressure Detection Circuitry * Level Detectors * Density Compensation * Level Detection Circuitry * Head Flow Meters * Other Flow Meters * Steam Flow Detection * Flow Circuitry * Synchro Equipment * Switches * Variable Output Devices * Position Indication Circuitry * Radiation Detection Terminology * Radiation Types * Gas-Filled Detector * Detector Voltage * Proportional Counter * Proportional Counter Circuitry * Ionization Chamber * Compensated Ion Chamber * Electroscope Ionization Chamber * Geiger-Müller Detector * Scintillation Counter * Gamma Spectroscopy * Miscellaneous Detectors * Circuitry And Circuit Elements * Source Range Nuclear Instrumentation * Intermediate Range Nuclear Instrumentation * Power Range Nuclear Instrumentation * Principles Of Control Systems * Control Loop Diagrams * Two Position Control Systems * Proportional Control Systems * Reset (Integral) Control Systems * Proportional Plus Reset Control Systems * Proportional Plus Rate Control Systems * Proportional-Integral-Derivative Control Systems * Controllers * Valve Actuators MATHEMATICS The Mathematics Fundamentals Handbook includes a review of introductory mathematics and the concepts and functional use of algebra, geometry, trigonometry, and calculus. Word problems, equations, calculations, and practical exercises that require the use of each of the mathematical concepts are also presented. * Calculator Operations * Four Basic Arithmetic Operations * Averages * Fractions * Decimals * Signed Numbers * Significant Digits * Percentages * Exponents * Scientific Notation * Radicals * Algebraic Laws * Linear Equations * Quadratic Equations * Simultaneous Equations * Word Problems * Graphing * Slopes * Interpolation And Extrapolation * Basic Concepts Of Geometry * Shapes And Figures Of Plane Geometry * Solid Geometric Figures * Pythagorean Theorem * Trigonometric Functions * Radians * Statistics * Imaginary And Complex Numbers * Matrices And Determinants * Calculus CHEMISTRY The Chemistry Handbook includes information on the atomic structure of matter; chemical bonding; chemical equations; chemical interactions involved with corrosion processes; water chemistry control, including the principles of water treatment; the hazards of chemicals and gases, and basic gaseous diffusion processes. * Characteristics Of Atoms * The Periodic Table * Chemical Bonding * Chemical Equations * Acids, Bases, Salts, And Ph * Converters * Corrosion Theory * General Corrosion * Crud And Galvanic Corrosion * Specialized Corrosion * Effects Of Radiation On Water Chemistry (Synthesis) * Chemistry Parameters * Purpose Of Water Treatment * Water Treatment Processes * Dissolved Gases, Suspended Solids, And Ph Control * Water Purity * Corrosives (Acids And Alkalies) * Toxic Compound * Compressed Gases * Flammable And Combustible Liquids ENGINEERING SYMBIOLOGY. The Engineering Symbology, Prints, and Drawings Handbook includes information on engineering fluid drawings and prints; piping and instrument drawings; major symbols and conventions; electronic diagrams and schematics; logic circuits and diagrams; and fabrication, construction, and architectural drawings. * Introduction To Print Reading * Introduction To The Types Of Drawings, Views, And Perspectives * Engineering Fluids Diagrams And Prints * Reading Engineering P&Ids * P&Id Print Reading Example * Fluid Power P&Ids * Electrical Diagrams And Schematics * Electrical Wiring And Schematic Diagram Reading Examples * Electronic Diagrams And Schematics * Examples * Engineering Logic Diagrams * Truth Tables And Exercises * Engineering Fabrication, Construction, And Architectural Drawings * Engineering Fabrication, Construction, And Architectural Drawing, Examples MATERIAL SCIENCE. The Material Science Handbook includes information on the structure and properties of metals, stress mechanisms in metals, failure modes, and the characteristics of metals that are commonly used in DOE nuclear facilities. * Bonding * Common Lattice Types * Grain Structure And Boundary * Polymorphism * Alloys * Imperfections In Metals * Stress * Strain * Young's Modulus * Stress-Strain Relationship * Physical Properties * Working Of Metals * Corrosion * Hydrogen Embrittlement * Tritium/Material Compatibility * Thermal Stress * Pressurized Thermal Shock * Brittle Fracture Mechanism * Minimum Pressurization-Temperature Curves * Heatup And Cooldown Rate Limits * Properties Considered * When Selecting Materials * Fuel Materials * Cladding And Reflectors * Control Materials * Shielding Materials * Nuclear Reactor Core Problems * Plant Material Problems * Atomic Displacement Due To Irradiation * Thermal And Displacement Spikes * Due To Irradiation * Effect Due To Neutron Capture * Radiation Effects In Organic Compounds * Reactor Use Of Aluminum MECHANICAL SCIENCE. The Mechanical Science Handbook includes information on diesel engines, heat exchangers, pumps, valves, and miscellaneous mechanical components. * Diesel Engines * Fundamentals Of The Diesel Cycle * Diesel Engine Speed, Fuel Controls, And Protection * Types Of Heat Exchangers * Heat Exchanger Applications * Centrifugal Pumps * Centrifugal Pump Operation * Positive Displacement Pumps * Valve Functions And Basic Parts * Types Of Valves * Valve Actuators * Air Compressors * Hydraulics * Boilers * Cooling Towers * Demineralizers * Pressurizers * Steam Traps * Filters And Strainers NUCLEAR PHYSICS AND REACTOR THEORY. The Nuclear Physics and Reactor Theory Handbook includes information on atomic and nuclear physics; neutron characteristics; reactor theory and nuclear parameters; and the theory of reactor operation. * Atomic Nature Of Matter * Chart Of The Nuclides * Mass Defect And Binding Energy * Modes Of Radioactive Decay * Radioactivity * Neutron Interactions * Nuclear Fission * Energy Release From Fission * Interaction Of Radiation With Matter * Neutron Sources * Nuclear Cross Sections And Neutron Flux * Reaction Rates * Neutron Moderation * Prompt And Delayed Neutrons * Neutron Flux Spectrum * Neutron Life Cycle * Reactivity * Reactivity Coefficients * Neutron Poisons * Xenon * Samarium And Other Fission Product Poisons * Control Rods * Subcritical Multiplication * Reactor Kinetics * Reactor
