This is an enlarged, updated, color-illustrated new edition of the definitive clinical reference on in vitro fertilization and assisted reproduction. It contains 37 chapters by top-ranked specialists from around the world covering every aspect of investigation and therapeutic options as taught and practiced at the world-famous Bourn Hall Clinic. Large format, double-column pages. Includes bibliographic references, procedures, protocols and information sheets, and index.
Personnel working in assisted reproductive technology often lack the opportunities for dedicated training in the specialized techniques and technologies required for the procedures. As such, success in the form of live birth rates can range from over 50% to less than 10% per treatment cycle. This comprehensive introductory textbook is an essential resource for trainee embryologists, medical students and nurses. The recent revolutions in biotechnology and molecular biology involved in delivering assisted reproductive services are thoroughly discussed. Basic knowledge such as the development and physiology of both male and female reproductive systems is covered, with practical aspects of IVF including gamete and embryo manipulation, cryopreservation and genetic testing explained in detail. A full description of the optimal structure and management of the IVF laboratory is given, helping ensure procedures are safe and effective. Extensive and highly detailed colour illustrations bring the content to life and aids readers in their understanding.
This book provides andrologists and other practitioners with reliable, up-to-date information on all aspects of male infertility and is designed to assist in the clinical management of patients. Clear guidance is offered on classification of infertility, sperm analysis interpretation and diagnosis. The full range of types and causes of male infertility are then discussed in depth. Particular attention is devoted to poorly understood conditions such as unexplained couple infertility and idiopathic male infertility, but the roles of diverse disorders, health and lifestyle factors and environmental pollution are also fully explored. Research considered stimulating for the reader is highlighted, reflecting the fascinating and controversial nature of the field. International treatment guidelines are presented and the role of diet and dietary supplements is discussed in view of their increasing importance. Clinicians will find that the book’s straightforward approach ensures that it can be easily and rapidly consulted.
Now in its revised and expanded second edition - including over 20 new chapters - this comprehensive textbook remains a unique and accessible description of the current and developing diagnostic and treatment techniques and technologies comprising in vitro fertilization (IVF). Arranged thematically in sections, each chapter covers a key topic in IVF in a sensible presentation. Parts one and two describe the planning, design and organization of an ART unit and IVF laboratory and equipment and systems, respectively. The sections that follow provide detailed descriptions of IVF techniques, embryo culture methods, sperm processing and selection, insemination procedures, micromanipulation, embryo evaluation, cryopreservation, and embryo transfer. Concluding sections address issues of management and regulation of ART labs across the globe, as well as special topics and emerging techniques and devices. Chapter authors, all experts in the field, contribute their expertise from around the world. With the addition of learning key points and review questions at the beginning and end of each chapter, this new edition of In Vitro Fertilization is a readily accessible, high quality instructional resource for reproductive medicine trainees at all levels. Practicing reproductive endocrinologists, urologists, and embryologists also will find value in the book, as will infertility researchers.
This fully updated new edition of a successful and popular practical guide is an indispensable account of modern in-vitro fertilization practice. Initial chapters cover theoretical aspects of gametogenesis and embryo development at the cellular and molecular level, while the latter half of the book describes the requisites for a successful IVF laboratory and the basic technologies in ART. Advanced techniques, including pre-implantation genetic diagnosis, vitrification and stem-cell technology, are comprehensively covered, providing up-to-date analyses of these groundbreaking technologies. This edition includes: • New practical techniques, including preservation of fertility for cancer patients, stem-cell biology/technology, vitrification and in-vitro maturation • A 'refresher' study review of fundamental principles of cell and molecular biology • The latest information available from animal and human research in reproductive biology Packed with a wealth of practical and scientific detail, this is a must for all IVF practitioners.
Bringing together the latest information on the organization, management and quality of in-vitro fertilization (IVF) units, this is the first true field guide for the clinician working in assisted reproductive technologies (ART). Divided thematically into four main sections, part one discussed the establishment and organization of the IVF unit, including location, design and construction, practical considerations for batching IVF cycles, and regulations and risk management. Part two, the largest section, covers the many aspects of overall quality management and its implementation – staff and patient management, cryobank and PGD/PGS management, and data management – as well as optimization of treatment outcomes and statistical process control analysis to assess quality variation. Part three addresses the relationship between IVF units and society at large, including the ethics of IVF treatment, as well as public/low-cost and private/corporate IVF units. Advertising and marketing for IVF units is discussed in part four, including the building and managing of websites and the use of traditional print and social media. With approximately five thousand IVF units worldwide and a growing number of training programs, Organization and Management of IVF Units is a key resource for clinic directors, unit managers, embryologists, quality experts, and students of reproductive medicine and clinical embryology.
The scourge of infertility defeated doctors and scientists down the ages. But since the breakthrough with in vitro fertilization (IVF) and other assisted reproductive technologies (ARTs) after 1980, almost every patient who hopes to have children can be helped. This book is the amazing story of how IVF came to America. It is told by Howard W. Jones, Jr., M.D. who, with his late wife Georgeanna Jones, M.D., was the American pioneer of 'test-tube babies.' For them, it was a 'retirement job' after finishing careers at Johns Hopkins University where he was an internationally-acclaimed reproductive surgeon and Georgeanna was the first director of gynecological endocrinology. That they succeeded so well against the odds late in their careers and in the teeth of opposition from right-to-life groups depended on a number of chance opportunities and the building of a 'dream-team.' Following the lead of Patrick Steptoe and Robert Edwards (Nobel Prize, 2010) and the birth of Louise Brown in Great Britain, they achieved the first test-tube baby in the Americas - Elizabeth Carr, born in Norfolk in 1981. IVF clinics have subsequently sprouted across the globe, and now account for over 60,000 births annually in the USA, and more than five million babies have been born worldwide. The rapid social acceptance of IVF owes a great deal to these doctors, and Howard Jones, now well past his hundredth year, still inspires researchers to improve treatment options, and debates the ethics of ARTs. When IVF was still in its infancy, the Joneses were invited to join a panel at the Vatican City to advise Pope John Paul II about IVF. They were unable to persuade that pontiff, although Howard harbors a hope that Pope Francis will eventually open his arms to the new treatment. No one has been more influential than him in propelling IVF forward in the USA, and this memoir is Howard's account of how the controversial research he steered became one of the great medical victories of our time.
In the 25 years since the first edition of Comprehensive Gynecology, many scientific advances have occurred in medical practice. The first four editions were largely the work of the original four editors: Drs. William Droegemueller, Arthur L. Herbst, Daniel R. Mishell, Jr., and Morton A. Stenchever...With the staggering volume of medical literature published and the complexities of the gynecologic subspecialties, we have collaborated with additional experts for the sixth edition. We've "examined disease" and added a new chapter on the interaction of medical diseases and female physiology. We've "investigated discord" with new authors to completely rewrite the emotional and psychological issues in gynecology and the legal issues for obstetrician-gynecologists. Other chapters have delved into the controversies in breast cancer screening, vitamin D use, the ongoing debates in hormone therapy, and vaginal mesh use for pelvic organ prolapse surgery. (from Preface -- MD Consult, viewed April 9, 2012)
