Now in its Fifth Edition, Clinical Epidemiology: The Essentials is a comprehensive, concise, and clinically oriented introduction to the subject of epidemiology. Written by expert educators, this text introduces students to the principles of evidence-based medicine that will help them develop and apply methods of clinical observation in order to form accurate conclusions. The Fifth Edition includes more complete coverage of systematic reviews and knowledge management, as well as other key topics such as abnormality, diagnosis, frequency and risk, prognosis, treatment, prevention, chance, studying cases and cause.
Focusing on improving the diagnosis, prognosis, and management of human disease, this book takes on the issues of research design, measurement, and evaluation which are critical to clinical epidemiology. This second edition of Clinical Epidemiology: Practice and Methods opens with how best to frame a clinical research question, the ethics associated with doing a research project in humans, and the definition of various biases that occur in clinical research. From there, it continues by examining issues of design, measurement, and analysis associated with various research designs, including determination of risk in longitudinal studies, assessment of therapy in randomized controlled clinical trials, and evaluation of diagnostic tests, and then delves into the more specialized area of clinical genetic research, before concluding with basic methods used in evidence-based decision making including critical appraisal, aggregation of multiple studies using meta-analysis, health technology assessment, clinical practice guidelines, development of health policy, translational research, how to utilize administrative databases, and knowledge translation. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and practical advice to ensure real world success. Comprehensive and authoritative, Clinical Epidemiology: Practice and Methods, Second Edition is intended to educate researchers on how to undertake clinical research and should be helpful not only to medical practitioners but also to basic scientists who want to extend their work to humans, to allied health professionals interested in scientific evaluation, and to trainees in clinical epidemiology.
“Methods of Clinical Epidemiology” serves as a text on methods useful to clinical researchers. It provides a clear introduction to the common research methodology specific to clinical research for both students and researchers. This book sets out to fill the gap left by texts that concentrate on public health epidemiology and focuses on what is not covered well in such texts. The four sections cover methods that have not previously been brought together in one text and serves as a second level textbook of clinical epidemiology methodology. This book will be of use to postgraduate students in clinical epidemiology as well as clinical researchers at the start of their careers.
The Third Edition of this popular text focuses on clinical-practice research methods. It is written by clinicians with experience in generating and answering researchable questions about real-world clinical practice and health care—the prevention, treatment, diagnosis, prognosis, and causes of diseases, the measurement of quality of life, and the effects of innovations in health services. The book has a problem-oriented and protocol-based approach and is written at an introductory level, emphasizing key principles and their applications. A bound-in CD-ROM contains the full text of the book to help the reader locate needed information.
Here is a book for clinicians, clinical investigators, trainees, and graduates who wish to develop their proficiency in the planning, execution, and interpretation of clinical and epidemiological research. Emphasis is placed on the design and analysis of research studies involving human subjects where the primary interest concerns principles of analytic (cause-and- effect) inference. The topic is presented from the standpoint of the clinician and assumes no previous knowledge of epidemiology, research design or statistics. Extensive use is made of illustrative examples from a variety of clinical specialties and subspecialties. The book is divided into three parts. Part I deals with epidemiological research design and analytic inference, including such issues as measurement, rates, analytic bias, and the main forms of observational and experimental epidemiological studies. Part II presents the principles and applications of biostatistics, with emphasis on statistical inference. Part III comprises four chapters covering such topics as diagnostic tests, decision analysis, survival (life-table) analysis, and causality.
Now updated with new data and examples throughout, Clinical Epidemiology: Principles, Methods, and Applications for Clinical Research, Second Edition is a comprehensive resource that introduces the reader to the basics of clinical epidemiology and explores the principles and methods that can be used to obtain quantitative evidence on the effects of interventions and on the diagnosis, etiology, and prognosis of disease. The everyday challenges of clinical research and the quantitative knowledge required to practice medicine are also examined, making this book a valuable reference for both graduate and undergraduate students in medicine and related disciplines, as well as for professionals involved in the design and conduct of clinical research.
Concise, fast-paced, intensive introduction to clinical research design for students and clinical research professionals Readers will gain sufficient knowledge to pass the United States Medical Licensing Examination part I section in Epidemiology
Using clinical examples and citing liberally from the peer-reviewed literature, this book shows how statistical priniciples can improve medical decisions.
Examining the principles and methods of research on the evaluation of factors affecting the outcome of illness, this volume emphasizes diagnostic and therapeutic interventions--the factors most readily modified by health care providers. The author discusses various ways of structuring observations on patient groups, and appraises the nature and strength of inferences drawn from those observations. Weiss also demonstrates how the results of this type of research--clinical epidemiologic research--can be incorporated into the decision-making process utilized in clinical medicine. The Second edition differs from the earlier one in a number of respects. It now employs a broader frame of reference, which includes studies such as those of adverse drug effects that use multipurpose computerized databases, and an expanded, explanation of the structure of evidence for drawing inferences, particularly evidence pertaining to the efficacy of testing. Examples have been modernized and replaced with more recent experimental results throughout the text, while decision analysis has been de-emphasized. The book's underlying theme, however, remains the same: the resources available to health care are finite and, through properly conducted research, the most efficient and safest ways of using these resources can and should be identified.
The new edition of this popular textbook remains a clear and practical introduction to epidemiology for students in all areas of health. By emphasising the role of epidemiology across a broad range of health monitoring and research, it gives students an understanding of the fundamental principles common to all areas of epidemiology. It also integrates the study of infectious and chronic diseases as well as public health and clinical epidemiology. Avoiding complex mathematics, it steps through the methods and potential problems underlying health data and reports, while maintaining a balance of rigour and clarity. The nuts-and-bolts of epidemiology are embedded in the wider international health perspective through recent and classical examples across different areas of health to engage students from a range of backgrounds. Concepts are illustrated with charts and graphs, and end-of-chapter questions test understanding (with answers provided). Online resources include further exercises, slides for teaching and useful weblinks.
