Peripheral Nerve Regeneration
Author: Giovanna Gambarotta
Publisher: Frontiers Media SA
Published: 2019-12-24
Total Pages: 302
ISBN-13: 2889632687
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Peripheral Nerve Regeneration
Author: Ana Colette Maurício
Publisher: BoD – Books on Demand
Published: 2017-05-31
Total Pages: 226
ISBN-13: 9535131656
DOWNLOAD EBOOKPeripheral nerve injuries are a high-incidence clinical problem that greatly affects patients' quality of life. Despite continuous refinement of microsurgery techniques, peripheral nerve repair still stands as one of the most challenging tasks in neurosurgery, as functional neuromuscular recovery is rarely satisfactory in these patients. Therefore, the improvement of surgical techniques and the clinical application of innovative therapies have been intensively studied worldwide. Direct nerve repair with epineural end-to-end sutures is still the gold standard treatment for severe neurotmesis injuries but only in cases where well-vascularized tension-free coaptation can be achieved. When peripheral nerve injury originates a significant gap between the nerve stumps, nerve grafts are required, with several associated disadvantages. Therefore, the development of scaffolds by tissue engineering can provide efficient treatment alternatives to stimulate optimum clinical outcome. Nerve conduit tailoring involves reaching ideal wall pores, using electrospinning techniques in their fabrication, surface coating with extracellular matrix materials, and adding of growth factors or cell-based therapies, among other possibilities. Also, intraluminal cues are employed such as the filling with hydrogels, inner surface modification, topographical design, and the introduction of neurotrophic factors, antibiotics, anti-inflammatories and other pharmacological agents. A comprehensive state of the art of surgical techniques, tissue-engineered nerve graft scaffolds, and their application in nerve regeneration, the advances in peripheral nerve repair and future perspectives will be discussed, including surgeons' and researchers' own large experience in this field of knowledge.
Postgraduate Orthopaedics
Author: Paul A. Banaszkiewicz
Publisher: Cambridge University Press
Published: 2012-08-16
Total Pages: 301
ISBN-13: 1107627362
DOWNLOAD EBOOKThe must-have book for candidates preparing for the oral component of the FRCS (Tr and Orth).
Electrospinning for Tissue Regeneration
Author: L Bosworth
Publisher: Elsevier
Published: 2011-06-21
Total Pages: 425
ISBN-13: 085709291X
DOWNLOAD EBOOKElectrospinning is a simple and highly versatile method for generating ultrathin fibres with diameters ranging from a few micrometres to tens of nanometres. Although most commonly associated with textile manufacturing, recent research has proved that the electrospinning technology can be used to create organ components and repair damaged tissues. Electrospinning for tissue regeneration provides a comprehensive overview of this innovative approach to tissue repair and regeneration and examines how it is being employed within the biomaterials sector.The book opens with an introduction to the fundamentals of electrospinning. Chapters go on to discuss polymer chemistry, the electrospinning process, conditions, control and regulatory issues. Part two focuses specifically on electrospinning for tissue regeneration and investigates its uses in bone, cartilage, muscle, tendon, nerve, heart valve, bladder, tracheal, dental and skin tissue regeneration before concluding with a chapter on wound dressings. Part three explores electrospinning for in vitro applications. Chapters discuss cell culture systems for kidney, pancreatic and stem cell research.With its distinguished editors and international team of expert contributors, Electrospinning for tissue regeneration is a valuable reference tool for those in academia and industry concerned with research and development in the field of tissue repair and regeneration. - Provides a comprehensive overview of this innovative approach to tissue repair and regeneration covering issues from polymer chemistry to the regulatory process - Examines employment within the biomaterials sector, reviewing extensive applications in areas such as uses in bone, muscle tendon, heart valve and tissue regeneration - Explores electrospinning for in vitro applications and discusses cell culture systems for kidney, pancreatic and stem cell research
Peptide-Based Materials
Author: Timothy Deming
Publisher: Springer Science & Business Media
Published: 2012-01-10
Total Pages: 184
ISBN-13: 3642271391
DOWNLOAD EBOOKSynthesis of Polypeptides by Ring-Opening Polymerization of α-Amino Acid N-Carboxyanhydrides, by Jianjun Cheng and Timothy J. Deming.- Peptide Synthesis and Self-Assembly, by S. Maude, L. R. Tai, R. P. W. Davies, B. Liu, S. A. Harris, P. J. Kocienski and A. Aggeli.- Elastomeric Polypeptides, by Mark B. van Eldijk, Christopher L. McGann, Kristi L. Kiick andJan C. M. van Hest.- Self-Assembled Polypeptide and Polypeptide Hybrid Vesicles: From Synthesis to Application, by Uh-Joo Choe, Victor Z. Sun, James-Kevin Y. Tan and Daniel T. Kamei.- Peptide-Based and Polypeptide-Based Hydrogels for Drug Delivery and Tissue Engineering, by Aysegul Altunbas and Darrin J. Pochan.-
Biomaterials
Author: Rosario Pignatello
Publisher: BoD – Books on Demand
Published: 2011-11-16
Total Pages: 474
ISBN-13: 9533076615
DOWNLOAD EBOOKThese contribution books collect reviews and original articles from eminent experts working in the interdisciplinary arena of biomaterial development and use. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different synthetic and engineered biomaterials. Contributions were selected not based on a direct market or clinical interest, but on results coming from a very fundamental studies. This too will allow to gain a more general view of what and how the various biomaterials can do and work for, along with the methodologies necessary to design, develop and characterize them, without the restrictions necessary imposed by industrial or profit concerns. Biomaterial constructs and supramolecular assemblies have been studied, for example, as drug and protein carriers, tissue scaffolds, or to manage the interactions between artificial devices and the body. In this volume of the biomaterial series have been gathered in particular reviews and papers focusing on the application of new and known macromolecular compounds to nanotechnology and nanomedicine, along with their chemical and mechanical engineering aimed to fit specific biomedical purposes.
Novel Biomaterials for Regenerative Medicine
Author: Heung Jae Chun
Publisher: Springer
Published: 2018-10-24
Total Pages: 533
ISBN-13: 9811309477
DOWNLOAD EBOOKThis book explores in depth a wide range of new biomaterials that hold great promise for applications in regenerative medicine. The opening two sections are devoted to biomaterials designed to direct stem cell fate and regulate signaling pathways. Diverse novel functional biomaterials, including injectable nanocomposite hydrogels, electrosprayed nanoparticles, and waterborne polyurethane-based materials, are then discussed. The fourth section focuses on inorganic biomaterials, such as nanobioceramics, hydroxyapatite, and titanium dioxide. Finally, up-to-date information is provided on a wide range of smart natural biomaterials, ranging from silk fibroin-based scaffolds and collagen type I to chitosan, mussel-inspired biomaterials, and natural polymeric scaffolds. This is one of two books to be based on contributions from leading experts that were delivered at the 2018 Asia University Symposium on Biomedical Engineering in Seoul, Korea – the companion book examines in depth the latest enabling technologies for regenerative medicine.
Extremity Replantation
Author: A. Neil Salyapongse
Publisher: Springer
Published: 2014-11-05
Total Pages: 220
ISBN-13: 1489975160
DOWNLOAD EBOOKExtremity Replantation is a comprehensive text covering all aspects of the upper and lower limb, with an emphasis on state-of-the-art techniques in the surgical and medical management of amputation and avulsion injuries as well as the current understanding of the recovery of function following replantation. It is organized following anatomical zones – thumb, digits, wrist, forearm and elbow; foot, ankle and lower leg – with special chapters dedicated to issues common to all replants, such as complications, medical management, nerve recovery and rehabilitation. Furthermore, the international team of authors demonstrates approaches from the entire spectrum of replantation care specialists, including plastic and reconstructive surgeons, orthopedists, and hand therapists. Generously illustrated with intra-operative photos, this book will serve as a standard reference for orthopedic, reconstructive, plastic, and hand surgeons as well as physicians or ancillary medical staff caring for the replant patient.
Advanced Trauma and Surgery
Author: Xiaobing Fu
Publisher: Springer
Published: 2016-11-15
Total Pages: 455
ISBN-13: 9811024251
DOWNLOAD EBOOKThis book discusses different aspects of trauma surgery, ranging from the various types of trauma and their management, infection, sepsis and inflammation to tissue injury and repair in trauma. It discusses cellular, molecular and genetic research findings and their role in pathogenesis in trauma and injury. In addition, it highlights the translational application of advanced theories and technologies in the management of trauma patients. This book is a valuable resource for anyone involved in the management of severe trauma damage to tissues wanting to reduce early mortality and improve patients' quality of life.
Bacterial NanoCellulose
Author: Miguel Gama
Publisher: CRC Press
Published: 2016-04-19
Total Pages: 315
ISBN-13: 1439869928
DOWNLOAD EBOOKThe first book dedicated to the potential applications and unique properties of bacterial cellulose (BC), this seminal work covers the basic science, technology, and economic impact of this bulk chemical as well as the companies and patents that are driving the field. It reviews the biosynthesis and properties of BC, including genetics and characterization; discusses the advancing technology as it relates to product development, bioreactors, and production; and analyzes the economic impact of BC on a diverse range of industry applications, including materials and biomaterials, biological and polymer sciences, and electromechanical engineering.
