Cell Surface Carbohydrate Chemistry
Cell Surface Carbohydrate Chemistry

Author: Robert E. Harmon

Publisher: Elsevier

Published: 2013-09-17

Total Pages: 376

ISBN-13: 1483273393

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Cell Surface Carbohydrate Chemistry is a collection of papers from a symposium of the same title held in San Francisco, U.S.A. on September 1-2, 1976. The book discusses cell biology and carbohydrates, particularly oligosaccharides that make up the glycoproteins and glycolipids in the cell membrane of normal neoplastic cells. One paper discusses the involvement of membranes in the biosynthesis of glycoproteins. One author also analyzes the glycoproteins from the surface of tumor cells. The glycoproteins have complex saccharide structures similar to virus transformed fibroblasts or transformed epithelial cells. Another paper cites the concepts made by Abercrombie and Ambrose regarding distinct galactosyltransferase activity released by tumor cells. Another paper addresses a hypothetical mechanism to explain the control of cell growth by nucleoside efflux through the membrane. One author analyzes the basis for the selectivity of some cancer chemotherapeutic agents—these can also have an effect in the immunity responses of the host against cancer cells. This book can prove useful for the medically-oriented investigator, the biologist, and the scientist involved in molecular chemistry and cancer research.

Cell Surface Carbohydrates and Cell Development
Cell Surface Carbohydrates and Cell Development

Author: Minoru Fukuda

Publisher: CRC Press

Published: 1991-12-13

Total Pages: 342

ISBN-13: 9780849364358

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Cell Surface Carbohydrates and Cell Development summarizes knowledge on the structure and function of cell surface carbohydrates in development and differentiation. The chapters include reviews on the expression of cell type-specific carbohydrates and their roles in cell-cell interaction. In particular, the role of cell surface carbohydrates in immune cell response, malignant transformation, fertilization, and neural cell development are addressed. This includes the exciting discovery about the role of adhesive molecules in leukocyte-endothellium interaction. Cell Surface Carbohydrates and Cell Development also summarizes the latest knowledge on structure and biosynthesis of carbohydrates, the role of specific carbohydrate modification, and animal lectins. The book will be useful to researchers and students interested in the biology of glycoproteins and biotechnology.

Carbohydrate Chemistry
Carbohydrate Chemistry

Author: Amelia Pilar Rauter

Publisher: Royal Society of Chemistry

Published: 2011

Total Pages: 411

ISBN-13: 1849731543

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Carbohydrate Chemistry provides review coverage of all publications relevant to the chemistry of monosaccharides and oligosaccharides in a given year. The amount of research in this field appearing in the organic chemical literature is increasing because of the enhanced importance of the subject, especially in areas of medicinal chemistry and biology. In no part of the field is this more apparent than in the synthesis of oligosaccharides required by scientists working in glycobiology. Clycomedicinal chemistry and its reliance on carbohydrate synthesis is now very well established, for example, by the preparation of specific carbohydrate- based antigens, especially cancer-specific oligosaccharides and glycoconjugates. Coverage of topics such as nucleosides, amino-sugars, alditols and cyclitols also covers much research of relevance to biological and medicinal chemistry. Each volume of the series brings together references to all published work in given areas of the subject and serves as a comprehensive database for the active research chemist Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.

Carbohydrate Chemistry, Biology and Medical Applications
Carbohydrate Chemistry, Biology and Medical Applications

Author: Hari G. Garg

Publisher: Elsevier

Published: 2011-09-06

Total Pages: 431

ISBN-13: 0080558143

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The finding by Emil Fischer that glucose and fructose on treatment with phenylhydrazine gave the identical osazone led him to the elucidation of stereochemistry of carbohydrates. Since then, progress in the field of carbohydrates has been amazing with the unraveling their basic structure, biosynthesis, immunology, functions, and clinical uses, for pure carbohydrates and for protein-linked carbohydrates (glycoproteins and proteoglycans). The chapters in Carbohydrate Chemistry, Biology and Medical Applications present a logical sequence leading from the chemistry and biochemistry of carbohydrates, followed by their role in various pathological conditions, to carbohydrates as potential therapeutic and diagnostic agents. This book offers a detailed panoramic review of the chemistry and biology of carbohydrates for chemists, biologists and health professionals. Each chapter is authored by contributors expert in the particular area of research. - Explains how carbohydrates are important to life - Details the chemistry, biology and medical aspects of carbohydrates - Interdisciplinary and international team of authors

Advances in Carbohydrate Chemistry and Biochemistry
Advances in Carbohydrate Chemistry and Biochemistry

Author:

Publisher: Academic Press

Published: 2013-11-21

Total Pages: 337

ISBN-13: 0124081134

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Since its inception in 1945, this serial has provided critical and informative articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry. - Features contributions from leading authorities and industry experts - Informs and updates on all the latest developments in the field

Cell Surface Glycolipids
Cell Surface Glycolipids

Author: Charles Crawford Sweeley

Publisher:

Published: 1980

Total Pages: 520

ISBN-13:

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Based on a Symposium Sponsored by the Division of Carbohydrate Chemistry at the 178th Meeting of the American Chemical Society, Washington, D. C. , September 11-14 1979.

Biology and Chemistry of Eukaryotic Cell Surfaces
Biology and Chemistry of Eukaryotic Cell Surfaces

Author: E.Y.C. Lee

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 381

ISBN-13: 0323153194

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Biology and Chemistry of Eucaryotic Cell Surfaces contains the proceedings of the Miami Winter Symposia, held on January 14- 15, 1974 and organized by the Department of Biochemistry, University of Miami School of Medicine, in Miami, Florida. Organized into 27 chapters, separating the manuscripts presented at the symposium, this book presents the stochastic studies on cell surface stickiness and the adhesion and aggregation of blood platelets. This text also explains the cell-contact and transformation-induced changes in the dynamic organization of normal and neoplastic cell plasma membranes and their role in lectin-mediated toxicity toward tumor cells. It also looks into the chemical components of surface membranes related to biological properties, carbohydrate antigens of cell surfaces, and molecular orientation of erythrocyte membrane glycoproteins. Some other chapters discuss the cell envelope glycoprotein biosynthesis in fungi, cellular lectin receptors, and topographical alterations of the fat cell surface membrane elicited by concanavalin A. Immunochemical evidence for putrescine sites on the membrane of mammalian cells, as well as the fractionation and biosynthesis of membrane components in erythroid cells, are also described.

Computer Assisted Modeling
Computer Assisted Modeling

Author: National Research Council

Publisher: National Academies Press

Published: 1987-02-01

Total Pages: 186

ISBN-13: 0309062284

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In much of biology, the search for understanding the relation between structure and function is now taking place at the macromolecular level. Proteins, nucleic acids, and polysaccharides are macromolecule--polymers formed from families of simpler subunits. Because of their size and complexity, the polymers are capable of both inter- and intramolecular interactions. These interactions confer upon the polymers distinctive three-dimensional shapes. These tertiary configurations, in turn, determine the function of the macromolecule. Computers have become so inextricably involved in empirical studies of three-dimensional macromolecular structure that mathematical modeling, or theory, and experimental approaches are interrelated aspects of a single enterprise.

Essentials of Carbohydrate Chemistry
Essentials of Carbohydrate Chemistry

Author: John F. Robyt

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 411

ISBN-13: 1461216222

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This is the first broad treatment of carbohydrate chemistry in many years, and presents the structures, reactions, modifications, and properties of carbohydrates. Woven throughout the text are discussions of biological properties of carbohydrates, their industrial applications, and the history of the field of carbohydrate chemistry. Written for students as well as practising scientists, this textbook and handy reference will be of interest to a wide range of disciplines: biochemistry, chemistry, food and nutrition, microbiology, pharmacology, and medicine.

Essentials of Glycobiology
Essentials of Glycobiology

Author: Ajit Varki

Publisher: CSHL Press

Published: 1999

Total Pages: 694

ISBN-13: 9780879696818

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Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.