Cell Migration in Development, Health and Disease
Cell Migration in Development, Health and Disease

Author: Anke Brüning-Richardson

Publisher: Springer

Published: 2024-10-18

Total Pages: 0

ISBN-13: 9783031645310

DOWNLOAD EBOOK

This textbook gives an insight into the importance of cell migration in health during development, wound healing and immune responses as well as in disease with particular focus on cancer. The reader will learn about the different ways cells migrate to allow cellular changes during development to occur, as well as responses to injury and threat by foreign invaders. Cell migration is a driver of invasion and ultimately metastasis in cancer and as such we will give examples from highly aggressive cancer such as brain tumours. The book also includes an introduction to mathematical modelling to predict cell migration, information on the development of software for analysis of data generated in 2D and 3D as well as recent developments in the investigations into cell migration using 3D bioprinting. This textbook will be a great learning tool for advanced undergraduate students and Master students with the relevant science degrees such as in cell biology, developmental biology, cancer research, and tumour biology.

Cell Migration
Cell Migration

Author: Frank Entschladen

Publisher: Karger Medical and Scientific Publishers

Published: 2010

Total Pages: 185

ISBN-13: 380559321X

DOWNLOAD EBOOK

Cell migration is a highly complex process which involves several compartments of the cell, including surface receptors, signalling elements and the cytoskeleton. It plays an essential role in embryogenesis, wound healing and inflammatory responses, and a dysregulation of cell movement can cause pathological states such as developmental defects, chronic inflammation, cancer invasion and metastasis. Covering extracellular regulatory signals and intracellular signal transduction pathways as well as the molecular mechanisms of migration in stem cells, leukocytes and tumor cells in the adult human organism, this book summarizes the current state of knowledge about cell migration. In the first part, the major aspects of different migratory cells in health and disease are covered, with special emphasis on T lymphocytes. The second part provides a comprehensive overview of the principal molecular mechanisms of migration such as adhesion receptors, cytoskeletal rearrangements and locomotor force generation, which, together, can be referred to as a cell's 'migrosome'.With contributions by eminent international scientists from different disciplines this book will serve as a valuable resource not only for researchers in cell biology, immunology and oncology, but also for clinicians who wish to learn more about the role of migratory processes in health and disease.

Mechanobiology in Health and Disease
Mechanobiology in Health and Disease

Author: Stefaan Verbruggen

Publisher: Academic Press

Published: 2018-08-09

Total Pages: 530

ISBN-13: 0128129530

DOWNLOAD EBOOK

Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. Provides an essential digest of primary research from many fields and disciplines in one convenient volume Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science

Cell Movement in Health and Disease
Cell Movement in Health and Disease

Author: Michael Schnoor

Publisher: Academic Press

Published: 2022-03-30

Total Pages: 386

ISBN-13: 0323901964

DOWNLOAD EBOOK

Cell Movement in Health and Disease brings the several scientific domains related to the phenomena together, establishing a consistent foundation for researchers in this exciting field. The content is presented in four main section. The first explores the foundations of Cell Movement, including overviews of cellular structure, signaling, physiology, motion-related proteins, and the interface with the cellular membrane. The second part covers the biological aspects of cellular movement, starting with chemical and mechanical sensing, describing the types of cell movement, mechanics at cell level, cell physiology, collective behavior, and the connections with the extracellular matrix. The following chapters provide an overview of the molecular machinery involved and cell-type specific movement. The third part of the book is dedicated to the translational aspects of cell movement, highlighting the key conditions associated with cell movement dysfunction, like cell invasion in cancer, wound healing, developmental issues, neurological dysfunctions, and immune response. The final part of the book covers key methods and modeling tools for cell movement research, including predictive mathematical models, in vitro and in vivo methods, biophysical and bioinformatics tools. Cell Movement in Health and Disease is the ideal reference for scientists from different backgrounds converging to expand the understanding of this key cellular process. Cellular and molecular biologists will gain a better understanding of the physical principals operating at cellular level while biophysicist and biomedical engineers will benefit from the solid biology foundation provided by the book. - Combines Biology, Physics and Modeling of cellular movement in one single source - Updated with the current understanding of the field - Includes key research methods for cell movement investigation - Cover translational aspects of cellular movement

Lymphocyte Trafficking in Health and Disease
Lymphocyte Trafficking in Health and Disease

Author: Raffaele Badolato

Publisher: Springer Science & Business Media

Published: 2006-09-05

Total Pages: 249

ISBN-13: 376437442X

DOWNLOAD EBOOK

This book deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention. It offers a series of international contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease, and has a special focus on diseases and targets of therapeutical intervention. The book will interest researchers and clinicians from inflammation research.

Molecular Biology of B Cells
Molecular Biology of B Cells

Author: Tasuku Honjo

Publisher: Academic Press

Published: 2014-12-22

Total Pages: 0

ISBN-13: 9780123979339

DOWNLOAD EBOOK

Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.

Cell Migration in Development and Disease
Cell Migration in Development and Disease

Author: Doris Wedlich

Publisher: John Wiley & Sons

Published: 2006-03-06

Total Pages: 398

ISBN-13: 3527604073

DOWNLOAD EBOOK

Cell Migration matches nearly all research areas in cell and developmental biology, genetics, and biomedicine. The field shows radical progress powered by the combination of new genomic tools, cell labeling techniques and the incorporation of new model systems. This is the first book to comprehensively cover cell migration from the identification of molecular mechanisms to the understanding of certain pathological disorders and cancer development.