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Author: Luca Formaggia
Publisher: Springer Science & Business Media
Published: 2010-06-27
Total Pages: 528
ISBN-13: 8847011523
DOWNLOAD EBOOKMathematical models and numerical simulations can aid the understanding of physiological and pathological processes. This book offers a mathematically sound and up-to-date foundation to the training of researchers and serves as a useful reference for the development of mathematical models and numerical simulation codes.
Author: Alfio Quarteroni
Publisher: Cambridge University Press
Published: 2019-05-09
Total Pages: 291
ISBN-13: 110848039X
DOWNLOAD EBOOKAddresses the mathematical and numerical modelling of the human cardiovascular system, from patient data to clinical applications.
Author: Alfio Quarteroni
Publisher: Cambridge University Press
Published: 2019-05-09
Total Pages: 291
ISBN-13: 1108570534
DOWNLOAD EBOOKMathematical and numerical modelling of the human cardiovascular system has attracted remarkable research interest due to its intrinsic mathematical difficulty and the increasing impact of cardiovascular diseases worldwide. This book addresses the two principal components of the cardiovascular system: arterial circulation and heart function. It systematically describes all aspects of the problem, stating the basic physical principles, analysing the associated mathematical models that comprise PDE and ODE systems, reviewing sound and efficient numerical methods for their approximation, and simulating both benchmark problems and clinically inspired problems. Mathematical modelling itself imposes tremendous challenges, due to the amazing complexity of the cardiovascular system and the need for computational methods that are stable, reliable and efficient. The final part is devoted to control and inverse problems, including parameter estimation, uncertainty quantification and the development of reduced-order models that are important when solving problems with high complexity, which would otherwise be out of reach.
Author: Jerry J. Batzel
Publisher: Springer
Published: 2012-12-14
Total Pages: 270
ISBN-13: 3642328822
DOWNLOAD EBOOKThis volume synthesizes theoretical and practical aspects of both the mathematical and life science viewpoints needed for modeling of the cardiovascular-respiratory system specifically and physiological systems generally. Theoretical points include model design, model complexity and validation in the light of available data, as well as control theory approaches to feedback delay and Kalman filter applications to parameter identification. State of the art approaches using parameter sensitivity are discussed for enhancing model identifiability through joint analysis of model structure and data. Practical examples illustrate model development at various levels of complexity based on given physiological information. The sensitivity-based approaches for examining model identifiability are illustrated by means of specific modeling examples. The themes presented address the current problem of patient-specific model adaptation in the clinical setting, where data is typically limited.
Author: Piero Colli Franzone
Publisher: Springer
Published: 2014-10-30
Total Pages: 410
ISBN-13: 3319048015
DOWNLOAD EBOOKThis book covers the main mathematical and numerical models in computational electrocardiology, ranging from microscopic membrane models of cardiac ionic channels to macroscopic bidomain, monodomain, eikonal models and cardiac source representations. These advanced multiscale and nonlinear models describe the cardiac bioelectrical activity from the cell level to the body surface and are employed in both the direct and inverse problems of electrocardiology. The book also covers advanced numerical techniques needed to efficiently carry out large-scale cardiac simulations, including time and space discretizations, decoupling and operator splitting techniques, parallel finite element solvers. These techniques are employed in 3D cardiac simulations illustrating the excitation mechanisms, the anisotropic effects on excitation and repolarization wavefronts, the morphology of electrograms in normal and pathological tissue and some reentry phenomena. The overall aim of the book is to present rigorously the mathematical and numerical foundations of computational electrocardiology, illustrating the current research developments in this fast-growing field lying at the intersection of mathematical physiology, bioengineering and computational biomedicine. This book is addressed to graduate student and researchers in the field of applied mathematics, scientific computing, bioengineering, electrophysiology and cardiology.
Author: Daniele Boffi
Publisher: Springer
Published: 2018-11-03
Total Pages: 252
ISBN-13: 3319966499
DOWNLOAD EBOOKThe book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. It covers a wide range of topics, from the assimilation of clinical data to the development of mathematical and computational models, including with parameters, as well as their efficient numerical solution, and both in-vivo and in-vitro validation. It also considers applications of relevant clinical interest. This book is intended for graduate students and researchers in the field of bioengineering, applied mathematics, computer, computational and data science, and medicine wishing to become involved in the highly fascinating task of modeling the cardiovascular system.
Author: Jerry J. Batzel
Publisher: SIAM
Published: 2007-09-20
Total Pages: 289
ISBN-13: 0898717450
DOWNLOAD EBOOKCardiovascular and Respiratory Systems: Modeling, Analysis, and Control uses a principle-based modeling approach and analysis of feedback control regulation to elucidate the physiological relationships. Models are arranged around specific questions or conditions, such as exercise or sleep transition, and are generally based on physiological mechanisms rather than on formal descriptions of input-output behavior. The authors ask open questions relevant to medical and clinical applications and clarify underlying themes of physiological control organization. Current problems, key issues, developing trends, and unresolved questions are highlighted. Researchers and graduate students in mathematical biology and biomedical engineering will find this book useful. It will also appeal to researchers in the physiological and life sciences who are interested in mathematical modeling.
Author: Alfio Quarteroni
Publisher: Springer Nature
Published: 2022-12-15
Total Pages: 136
ISBN-13: 3030961621
DOWNLOAD EBOOKSimulating the behavior of a human heart, predicting tomorrow's weather, optimizing the aerodynamics of a sailboat, finding the ideal cooking time for a hamburger: to solve these problems, cardiologists, meteorologists, sportsmen, and engineers can count on math help. This book will lead you to the discovery of a magical world, made up of equations, in which a huge variety of important problems for our life can find useful answers.
Author: Michel R. Labrosse
Publisher: CRC Press
Published: 2018-09-13
Total Pages: 386
ISBN-13: 1315280280
DOWNLOAD EBOOKThe objective of this book is to illustrate in specific detail how cardiovascular mechanics stands as a common pillar supporting such different clinical successes as drugs for high blood pressure, prosthetic heart valves and coronary artery bypass grafting, among others. This information is conveyed through a comprehensive treatment of the overarching principles and theories that are behind mechanobiological processes, aortic and arterial mechanics, atherosclerosis, blood and microcirculation, hear valve mechanics, as well as medical devices and drugs. Examines all major theoretical and practical aspects of mechanical forces related to the cardiovascular system. Discusses a unique coverage of mechanical changes related to an aging cardiovascular system. Provides an overview of experimental methods in cardiovascular mechanics. Written by world-class researchers from Canada, the US and EU. Extensive references are provided at the end of each chapter to enhance further study. Michel R. Labrosse is the founder of the Cardiovascular Mechanics Laboratory at the University of Ottawa, where he is a full professor within the Department of Mechanical Engineering. He has been an active researcher in academia along with being heavily associated with the University of Ottawa Heart Institute. He has authored or co-authored over 90 refereed communications, and supervised or co-supervised over 40 graduate students and post-docs.
Author: Peregrina Quintela Estévez
Publisher: Springer Nature
Published: 2021-03-01
Total Pages: 161
ISBN-13: 3030592235
DOWNLOAD EBOOKThis book results from the talks presented at the First Conference on Transfer between Mathematics & Industry (CTMI 2019). Its goal is to promote and disseminate the mathematical tools for Statistics & Big Data, MSO (Modeling, Simulation and Optimization) and their industrial applications. In this volume, the reader will find innovative advances in the automotive, energy, railway, logistics, and materials sectors. In addition, Advances CTMI 2019 promotes the opening of new research lines aiming to provide suitable solutions for the industrial and societal challenges. Fostering effective interaction between Academia and Industry is our main purpose with this book. CTMI conferences are one of the main forums where significant advances in industrial mathematics are presented, bringing together outstanding leaders from business, science and Academia to promote the use of mathematics for an innovative industry.
