Molecular Mechanisms in Yeast Carbon Metabolism

Molecular Mechanisms in Yeast Carbon Metabolism

Author: Jure Piškur

Publisher: Springer

Published: 2014-05-06

Total Pages: 328

ISBN-13: 3642550134

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Yeast is one of the most studied laboratory organisms and represents one of the most central models to understand how any eukaryote cell works. On the other hand, yeast fermentations have for millennia provided us with a variety of biotech products, like wine, beer, vitamins, and recently also with pharmaceutically active heterologous products and biofuels. A central biochemical activity in the yeast cell is the metabolism of carbon compounds, providing energy for the whole cell, and precursors for any of the final fermentation products. A complex set of genes and regulatory pathways controls the metabolism of carbon compounds, from nutrient sensing, signal transduction, transcription regulation and post-transcriptional events. Recent advances in comparative genomics and development of post-genomic tools have provided further insights into the network of genes and enzymes, and molecular mechanisms which are responsible for a balanced metabolism of carbon compounds in the yeast cell, and which could be manipulated in the laboratory to increase the yield and quality of yeast biotech products. This book provides a dozen of most comprehensive reviews on the recent developments and achievements in the field of yeast carbon metabolism, from academic studies on gene expression to biotechnology relevant topics.


Molecular Basis of Nutrition and Aging

Molecular Basis of Nutrition and Aging

Author: Marco Malavolta

Publisher: Academic Press

Published: 2016-04-15

Total Pages: 786

ISBN-13: 0128018275

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Molecular Basis of Nutrition and Aging: A Volume in the Molecular Nutrition Series focuses on the nutritional issues associated with aging and the important metabolic consequences of diet, nutrition, and health. The book is subdivided into four parts that reflect the impact of nutrition from a biomolecular level to individual health. In Part One, chapters explore the general aspects of aging, aging phenotypes, and relevant aspects of nutrition related to the elderly and healthy aging. Part Two includes molecular and cellular targets of nutrition in aging, with chapters exploring lipid peroxidation, inflammaging, anabolic and catabolic signaling, epigenetics, DNA damage and repair, redox homeostasis, and insulin sensitivity, among others. Part Three looks at system-level and organ targets of nutrition in aging, including a variety of tissues, systems, and diseases, such as immune function, the cardiovascular system, the brain and dementia, muscle, bone, lung, and many others. Finally, Part Four focuses on the health effects of specific dietary compounds and dietary interventions in aging, including vitamin D, retinol, curcumin, folate, iron, potassium, calcium, magnesium, zinc, copper, selenium, iodine, vitamin B, fish oil, vitamin E, resveratrol, polyphenols, vegetables, and fruit, as well as the current nutritional recommendations. Offers updated information and a perspectives on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of aging Explores how nutritional factors are involved in the pathogenesis of aging across body systems Investigates the molecular and genetic basis of aging and cellular senescence through the lens of the rapidly evolving field of molecular nutrition


Inborn Errors of Metabolism

Inborn Errors of Metabolism

Author: Brendan Lee

Publisher: Oxford Monographs on Medical G

Published: 2014-10-13

Total Pages: 393

ISBN-13: 0199797587

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This volume is an expansion on the known treatment model of IEMs, one that establishes an innovative pathway approach and provides a new authority on this family of disease. Alongside the standard cadre of molecular and clinical underpinnings, this book includes coverage of newborn screening and an overarching treatment of IEMs as complex diseases.


Forages, Volume 2

Forages, Volume 2

Author: Kenneth J. Moore

Publisher: John Wiley & Sons

Published: 2020-05-29

Total Pages: 968

ISBN-13: 1119436613

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Forages: The Science of Grassland Agriculture, 7th Edition, Volume II will extensively evaluate the current knowledge and information on forage agriculture. Chapters written by leading researchers and authorities in grassland agriculture are aggregated under section themes, each one representing a major topic within grassland science and agriculture. This 7th edition will include two new additional chapters covering all aspects of forage physiology in three separate chapters, instead of one in previous editions. Chapters will be updated throughout to include new information that has developed since the last edition. This new edition of the classic reference serves as a comprehensive supplement to An Introduction to Grassland Agriculture, Volume I.


Nutritional Epigenomics

Nutritional Epigenomics

Author:

Publisher: Academic Press

Published: 2019-07-20

Total Pages: 478

ISBN-13: 0128173106

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Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition’s role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet’s role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders. Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease. Empowers the reader to employ nutritional epigenomics approaches in their own research Discusses the latest topics in nutritional epigenomics in the regulation of aging, circadian rhythm, inheritance and fetal development, as well as metabolism and disease Offers a full grounding in epigenetic reprogramming and nutritional intervention in the treatment and prevention of disease, as informed by population-based studies


The Sulfate-Reducing Bacteria: Contemporary Perspectives

The Sulfate-Reducing Bacteria: Contemporary Perspectives

Author: J.M. Odom

Publisher: Springer Science & Business Media

Published: 2013-11-11

Total Pages: 308

ISBN-13: 1461392632

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Sulfate-reducing bacteria comprise a diverse and ecologically interactive group of anaerobic prokaryotes which share an extraordinary trait: growth by sulfate respiration with hydrogen sulfide as a major end-product. Sulfate-reducers are found in diverse environments ranging from estuaries to geological oil-bearing formations. They have attracted considerable scientific and commercial interest. These organisms have been actively investigated by researchers in microbial energetics, protein chemistry, ecology and more recently molecular biology. This interest has increased greatly over the past decade, and this volume presents the first book-length summary of our knowledge of sulfate-reducing bacteria in nearly 10 years. Featuring an introduction by the eminent microbiologist John Postgate and comprehensive reviews from recognized authorities, this book will be of interest to microbiologists with interests in physiology, evolution, and ecology.


Photosynthetic Nitrogen Assimilation and Associated Carbon and Respiratory Metabolism

Photosynthetic Nitrogen Assimilation and Associated Carbon and Respiratory Metabolism

Author: C.H. Foyer

Publisher: Springer Science & Business Media

Published: 2002-12-31

Total Pages: 300

ISBN-13: 0792363361

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This book focuses on the very latest developments in our understanding of how plants use light energy and fixed carbon to assimilate nitrate and ammonium into the organic compounds required for growth. From the partitioning of organic nitrogen within the photosynthetic apparatus, through the primary processes of reduction of nitrate and nitrite and the assimilation of ammonium and its cycling in photorespiration, the complex interactions inherent in the crosstalk between carbon and nitrogen assimilation are considered and exciting new developments such as nitric oxide production evaluated. Attention is paid throughout to the close coordination of photosynthetic and respiratory processes in nitrogen assimilation. Emerging concepts of the interdependence of chloroplasts and mitochondria are described, and essential communication, transport and signalling processes are highlighted.


Autotrophic Microbiology and One-Carbon Metabolism

Autotrophic Microbiology and One-Carbon Metabolism

Author: G.A. Codd

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 233

ISBN-13: 9400919786

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Autotrophic and methylotrophic microorganisms are able to grow at the expense of one-carbon compounds (e.g. carbon dioxide, formaldehyde) as the principal carbon sources for the synthesis of cell material, using light, inorganic compounds or one-carbon compounds as energy sources. The study of the special adaptations required in aerobic and anaerobic microorganisms to sustain an autotrophic or methylotrophic mode of life is a fascinating field of research for scientists from various disciplines. Current research efforts not only focus on fundamental aspects, i.e. metabolic pathways and their regulation, ecology, energy conversion and genetics, but also the possible application of these organisms, in waste water treatment, degradation of xenobiotics, single-cell protein production, as biocatalysts for the production of fine chemicals, draws strong attention. The aim of this series is to provide annual reviews on the biochemistry, physiology, ecology, genetics, and application of microbial autotrophs and methylotrophs. The scope of the series includes all aspects of the biology of these microbes, and will deal with phototrophic and chemolithotrophic prokaryotic autotrophs, carboxydobacteria, acetogenic-, methanogenic- and methylotrophic bacteria, as well as methylotrophic eukaryotes. The exciting advances made in recent years in the study of these organisms is reflected in the chapters of this first volume which have been written by experts in the field. We would like to express our sincere thanks to all the contributors for their stimulating and comprehensive chapters.


Biochemical Basis of Plant Breeding

Biochemical Basis of Plant Breeding

Author: Carlos A. Neyra

Publisher: CRC Press

Published: 2019-07-17

Total Pages: 265

ISBN-13: 1000697622

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First published in 1985: This book presents a comprehensive survey of progress and current knowledge of those biochemical processes with greater potential for the development of superior cultivars: Photosynthesis, photorespiration, nitrate assimilation, biological nitrogen fixation, and starch and protein synthesis.