How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease

Author: United States. Public Health Service. Office of the Surgeon General

Publisher:

Published: 2010

Total Pages: 728

ISBN-13:

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This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.


Cruciferous Vegetables, Isothiocyanates and Indoles

Cruciferous Vegetables, Isothiocyanates and Indoles

Author: International Agency for Research on Cancer

Publisher: IARC

Published: 2004

Total Pages: 282

ISBN-13: 9789283230090

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This publication sets outs the findings of an IARC Working Group, held in Lyon, France in November 2003, which considered the benefits of a diet rich in cruciferous vegetables in helping to reduce the risk of various cancers. Cruciferous vegetables, such as broccoli, cabbage, cauliflower, watercress and brussel sprouts, contain substantial amounts of compounds which have been shown to inhibit the growth of cancers. This publication reviews current knowledge on the topic, including data from human, experimental and mechanistic studies, as well as making recommendations for future research and public health policy options.


Cancer Care for the Whole Patient

Cancer Care for the Whole Patient

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2008-03-19

Total Pages: 455

ISBN-13: 0309134161

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Cancer care today often provides state-of-the-science biomedical treatment, but fails to address the psychological and social (psychosocial) problems associated with the illness. This failure can compromise the effectiveness of health care and thereby adversely affect the health of cancer patients. Psychological and social problems created or exacerbated by cancer-including depression and other emotional problems; lack of information or skills needed to manage the illness; lack of transportation or other resources; and disruptions in work, school, and family life-cause additional suffering, weaken adherence to prescribed treatments, and threaten patients' return to health. Today, it is not possible to deliver high-quality cancer care without using existing approaches, tools, and resources to address patients' psychosocial health needs. All patients with cancer and their families should expect and receive cancer care that ensures the provision of appropriate psychosocial health services. Cancer Care for the Whole Patient recommends actions that oncology providers, health policy makers, educators, health insurers, health planners, researchers and research sponsors, and consumer advocates should undertake to ensure that this standard is met.


A Cancer Source Book for Nurses

A Cancer Source Book for Nurses

Author: American Cancer Society

Publisher: Jones & Bartlett Learning

Published: 2004

Total Pages: 596

ISBN-13: 9780763732769

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Covers the most common cancers and strategies for nursing care.


The Cancer Lifeline Cookbook

The Cancer Lifeline Cookbook

Author: Kimberly Mathai

Publisher: Sasquatch Books

Published: 2010-06-01

Total Pages: 252

ISBN-13: 1570617171

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After 30 years of providing counseling and support for people living with cancer, the Cancer Lifeline organization knows that one of the main areas of interest for patients and their families is food and nutrition. What foods have been shown to help prevent the spread of cancer? What are the nutritional "rules" for people with cancer? In answer, this new edition of the organization's cookbook presents up-to-date nutritional information (including the Top Ten Super Foods that may protect and fight against cancer) along with practical strategies for making healthy eating a daily practice and suggestions for reducing the side effects of treatment. It features 100 easy-to-make recipes from the nation's top chefs and from some cancer patients and survivors, including Blueberry Breakfast Cake, Honey-Glazed Green Beans with Almonds, and Citrus Chicken. These resources and more make it a natural choice for cancer survivors, people living with cancer, and those interested in a health-conscious diet.


Pathology and Genetics of Tumours of Endocrine Organs

Pathology and Genetics of Tumours of Endocrine Organs

Author: Ronald A. DeLellis

Publisher: IARC

Published: 2004

Total Pages: 324

ISBN-13: 9789283224167

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This vol. was produced in collaboration with the International Academy of Pathology (IAP). - This publication reflects the views of a working group that convened for an editorial and consensus conference in Lyon, France, April 23-26, 2003


Betel-quid and Areca-nut Chewing and Some Areca-nut-derived Nitrosamines

Betel-quid and Areca-nut Chewing and Some Areca-nut-derived Nitrosamines

Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Publisher: IARC

Published: 2004

Total Pages: 354

ISBN-13: 9789283212850

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A working group of sixteen experts from seven countries re-evaluated the evidence of the carcinogenicity of betel-quid and areca-nut chewing and some areca-nut related nitrosamines. Betel-quid and areca-nut chewing are widely practised in many parts of Asia and in Asian-migrant communities elsewhere in the world. There are hundreds of millions of users worldwide. They evaluated betel quid with tobacco as carcinogenic to humans (Group 1) on the basis of sufficient evidence of an increased risk of cancer of the oral cavity, pharynx and oesophagus. The working group reviewed epidemiological studies of human cancer, mainly studies from India, Pakistan and Taiwan (China). Studies on betel quid with tobacco and areca nut with tobacco in experimental animals now also provide sufficient evidence of carcinogenicity. The working group also evaluated betel quid without tobacco as carcinogenic to humans (Group 1), on the basis of sufficient evidence of an increased risk of oral cancer. Studies on betel quid without tobacco and areca nut without tobacco in experimental animals now also provide sufficient evidence of carcinogenicity. Areca nut, a common ingredient of betel quid and many different chewing preparations, including those available commercially, has been observed to cause oral submucous fibrosis


The Health Consequences of Involuntary Exposure to Tobacco Smoke

The Health Consequences of Involuntary Exposure to Tobacco Smoke

Author:

Publisher:

Published: 2006

Total Pages: 736

ISBN-13:

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This Surgeon General's report returns to the topic of the health effects of involuntary exposure to tobacco smoke. The last comprehensive review of this evidence by the Department of Health and Human Services (DHHS) was in the 1986 Surgeon General's report, The Health Consequences of Involuntary Smoking, published 20 years ago this year. This new report updates the evidence of the harmful effects of involuntary exposure to tobacco smoke. This large body of research findings is captured in an accompanying dynamic database that profiles key epidemiologic findings, and allows the evidence on health effects of exposure to tobacco smoke to be synthesized and updated (following the format of the 2004 report, The Health Consequences of Smoking). The database enables users to explore the data and studies supporting the conclusions in the report. The database is available on the Web site of the Centers for Disease Control and Prevention (CDC) at http://www.cdc.gov/tobacco.


Cancer Cell Culture

Cancer Cell Culture

Author: Simon P. Langdon

Publisher: Springer Science & Business Media

Published: 2008-02-01

Total Pages: 346

ISBN-13: 1592594069

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The culture of cancer cells is routinely practiced in many academic research centers, biotechnology companies, and hospital laboratories. Cancer Cell Culture: Methods and Protocols describes easy-to-follow methods to guide both novice and more experienced researchers seeking to use new techniques in their laboratories. Our present understanding of the cell and molecular biology of cancer has been derived mainly from the use of cultured cancer cells and we cover a number of the most widely used assays to study function in current use. Part I introduces the basic concept of cancer cell culture and this is followed by a description of the general techniques used in many cell culture facilities. The importance of cell line characterization is now widely recognized and methods to characterize and authenticate cell lines are described in Part II. Part III covers the isolation and development of specific cancer cell types and provides valuable tips for those wishing to derive new cell line models. A wide range of procedures encompassing many of the key functional features of cancer cells are described in Part IV including assays to evaluate clonogenicity, cell proliferation, apoptosis, adhesion, migration, invasion, senescence, angiogenesis, and cell cycle parameters. Methods to modify cancer cells are described in Part V, including protocols for transfection, development of drug-resistance, immortalization, and transfer in vivo. In Part VI methods of coculture of different cell types and contamination of cell lines are covered.