Bone and Bone Seeking Radionuclides
Author: Vladimir Volf
Publisher:
Published: 1981
Total Pages: 172
ISBN-13:
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Health Risks of Radon and Other Internally Deposited Alpha-Emitters
Author: National Research Council
Publisher: National Academies Press
Published: 1988-02-01
Total Pages: 623
ISBN-13: 0309037891
DOWNLOAD EBOOKThis book describes hazards from radon progeny and other alpha-emitters that humans may inhale or ingest from their environment. In their analysis, the authors summarize in one document clinical and epidemiological evidence, the results of animal studies, research on alpha-particle damage at the cellular level, metabolic pathways for internal alpha-emitters, dosimetry and microdosimetry of radionuclides deposited in specific tissues, and the chemical toxicity of some low-specific-activity alpha-emitters. Techniques for estimating the risks to humans posed by radon and other internally deposited alpha-emitters are offered, along with a discussion of formulas, models, methods, and the level of uncertainty inherent in the risk estimates.
Nuclear Oncology
Author: H. William Strauss
Publisher: Springer Science & Business Media
Published: 2012-11-27
Total Pages: 873
ISBN-13: 0387488944
DOWNLOAD EBOOKThis book provides the reader with a comprehensive understanding of both the basic principles and the clinical applications of nuclear oncology imaging techniques. The authors have assembled a distinguished group of leaders in the field who provide valuable insight on the subject. The book also includes major chapters on the cancer patient and the pathophysiology of abnormal tissue, the evaluation of co-existing disease, and the diagnosis and therapy of specific tumors using functional imaging studies. Each chapter is heavily illustrated to assist the reader in understanding the clinical role of nuclear oncology in cancer disease therapy and management.
Targeted Radionuclide Therapy
Author: Tod W. Speer
Publisher: Lippincott Williams & Wilkins
Published: 2012-03-28
Total Pages: 564
ISBN-13: 1451153260
DOWNLOAD EBOOKRadioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.
Radionuclide and Hybrid Bone Imaging
Author: Ignac Fogelman
Publisher: Springer
Published: 2013-01-03
Total Pages: 1029
ISBN-13: 3642024009
DOWNLOAD EBOOKThis book, written by authors with national and international reputations in the field, covers all aspects of radionuclide and hybrid bone imaging. Introductory sections present the basic science and consider the current status and limitations of conventional radiological techniques. The underlying principles of PET-CT and SPECT-CT are carefully explained, and the value of different PET and SPECT tracers, assessed. The role of single- and dual-modality approaches in the imaging of benign bone diseases and malignancies is then discussed in detail in a series of well-illustrated chapters. The pathologies addressed include metabolic bone disease, arthritis, bone and joint infections, primary bone and soft tissue tumors, and metastases from breast and prostate cancer. A further section considers the role of bone scintigraphy in the pediatric patient, and the closing chapters focus on miscellaneous subjects, including bone densitometry and radionuclide targeted therapy.
Bone Scanning in Clinical Practice
Author: Ignac Fogelman
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 270
ISBN-13: 1447114078
DOWNLOAD EBOOKThe most frequently requested investigation in any nuclear medicine department remains the technetium-99m (99mTc)-labelled diphosphonate bone scan. Despite rapid advances in all imaging modalities. there has been no serious challenge to the role of bone scanning in the evaluation of the skeleton. The main reason for this is the exquisite sensitivity of the bone scan for lesion detection. combined with clear visualisation of the whole skeleton. In recent years several new diphosphonate agents have become available with claims for superior imaging of the skeleton. Essentially. they all have higher affinity for bone. thus allowing the normal skeleton to be visualised all the more clearly. However. as will be dis cussed. this may occur at some cost to the principal role of bone scanning. lesion detection. The major strength of nuclear medicine is its ability to provide functional and physiological information. With bone scanning this leads to high sensitivity for focal disease if there has been any disturbance of skeletal metabolism. However. in many other clinical situations. and particularly in metabolic bone disease. more generalised alteration in skeletal turnover may occur. and quantitation of diphosphonate uptake by the skeleton can provide valuable clinical information.
Sodium Fluoride PET/CT in Clinical Use
Author: Kalevi Kairemo
Publisher: Springer Nature
Published: 2019-11-04
Total Pages: 97
ISBN-13: 3030235777
DOWNLOAD EBOOKThis pocket book is the first of its kind on sodium fluoride (18F-NaF)-PET and addresses skeletal as well as cardiovascular applications. In malignant metastatic diseases 18F-NaF-PET has already demonstrated its benefits in cancer staging, re-staging, follow-up and response evaluation. It also has an emerging diagnostic role in the calcified soft-tissue metastases of primary bone tumours, and can be applied to evaluate cardiovascular diseases, such as calcifications in heart valves and peripheral vascular disease. The book is divided into 11 chapters: five on oncology, four addressing the general aspects of skeletal conditions, and two on cardiovascular diseases. It offers a valuable guide for referring colleagues, nuclear medicine physicians/radiologists and aid clinicians, and highlights the main applications and limitations of 18F-NaF-PET hybrid imaging (PET/CT).
Advancing Nuclear Medicine Through Innovation
Author: National Research Council
Publisher: National Academies Press
Published: 2007-09-11
Total Pages: 173
ISBN-13: 0309134153
DOWNLOAD EBOOKNearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.
New-Generation Bioinorganic Complexes
Author: Renata Jastrzab
Publisher: Walter de Gruyter GmbH & Co KG
Published: 2016-03-21
Total Pages: 325
ISBN-13: 3110386445
DOWNLOAD EBOOKBio-Inorganic compounds are successfully applied as therapeutic agents since decades. Thus, scientist designed new metal complexes bearing biomolecules as ligands, investigating their potential as bioactive and therapeutic agents. This book presents a comprehensive overview on materials design, substance classes and their characterization. This book is compiled for scientists interested in medical application of bioinspired materials.
Delayed Effects of Bone-seeking Radionuclides
Author: Charles W. Mays
Publisher:
Published: 1969
Total Pages: 548
ISBN-13:
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