How do mammals manage to maintain their body temperature within the same narrow range in environments as different as polar regions and hot deserts? This advanced text describes the morphological features and physiological mechanisms by which humans and other mammals maintain their body temperature within a narrow range despite large variations in climatic conditions and internal heat production. Its 19 chapters deal with the physics of heat exchange with the environment, and the autonomic and behavioural mechanisms available to control the loss and production of heat. The neuronal basis of temperature regulation and current concepts of the central nervous interface between temperature signals generated in the body and control mechanisms are examined in detail. This book is of invaluable help for undergraduates, postgraduates, teachers, physicians and scientists.
The physiology of man is a complex subject. Unfortunately the regulation of temperature in the human body is not always well explained in textbooks. Many conference proceedings on the subject have been produced that give excellent detail on research topics. However, the subject matter is rarely presented as a composite whole. New technology has broadened the scope of methods available for studying body temperature. Thermography in particular has made it possible to record in real time the temperature distribution of large areas of the body surface. Modem image processing methods permit dynamic studies to be carried out and detailed analyses made retrospectively-a tremendous advance over the complex and slow techniques formerly used by physiologists. Yet although the associa tion between disease and temperature is as old as medicine itself, beyond the implicit faith in the clinical mercury thermometer, other measuring techniques are finding a slow acceptance. This book is designed to put into perspective the critical factors that make up "body temperature. " Body temperature cannot be viewed as a static entity but rather must be seen as a dynamic process. An understanding of this phenomenon is important to all who use thermal imaging and measuring techniques in clinical medi cine. These methods have, in recent years, brought engineers, physi cists, technicians, and clinicians together. Inevitably, however, there v vi Preface are gaps and overlaps in technology and understanding.
This is a user-friendly monograph designed for medical students as well as graduate students and postdoctoral trainees in medicine and other health-related sciences who need a comprehensive overview of thermoregulation. It presents the bases of the modern concepts in thermal physiology and pathophysiology, bringing together the disciplines encompassed by this highly integrative field ? physiology, anatomy, biophysics, molecular and cellular biology, pharmacology, neuroscience, pathology, medicine, and others ? into a clear and concise form that can be read comfortably in a relatively short time. This text was conceived by the Commission on Thermal Physiology of the International Union of Physiological Sciences in response to its concern over the inadequate and outdated coverage of this topic in traditional textbooks. The membership of this Commission comprises international experts in each of the subfields of thermal physiology, with extensive research and teaching experience in their respective specialties. They are the authors of the chapters of this indispendable textbook.
The book Heat Shock Proteins in Neuroscience provides the most comprehensive review on contemporary knowledge on the role of HSP in signaling pathways relevant to a number of diseases. Using an integrative approach, the contributors provide a synopsis of novel mechanisms, signal transduction pathways. To enhance the ease of reading and comprehension, this book has been subdivided into various section including; Section I, reviews current progress on our understanding of Neurological Aspects of HSP; Section II, focuses on Aspects of HSP in Neurodegenerative Diseases and Disorders, Section III, emphasizes the importance of HSP in Multiple Sclerosis; Section IV, reviews critical Aspects of HSP in Alzheimer’s Disease and Section V, gives a comprehensive update of the Development of HSP-Based Therapies for Neurological Disorders. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for starters and professionals in the fields of Neurology and Neurosciences, Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
With the help of extensive data tables and figures, this book explains the key facets of rodent thermal physiology, including neurological control and gender and intraspecies variations. The book should therefore find use in government, academic or industrial laboratories whose researchers are working with rodents.
Whether you're a polar bear giving birth to cubs in an Arctic winter, a camel going days without water in the desert heat, or merely a suburbanite without air conditioning in a heat wave, your comfort and even survival depend on how well you adapt to extreme temperatures. In this entertaining and illuminating book, biopsychologist Mark Blumberg explores the many ways that temperature rules the lives of all animals (including us). He moves from the physical principles that govern the flow of heat in and out of our bodies to the many complex evolutionary devices animals use to exploit those principles for their own benefit. In the process Blumberg tells wonderful stories of evolutionary and scientific ingenuity--how penguins withstand Antarctic winters by huddling together by the thousands, how vulnerable embryos of many species are to extremes of temperature during their development, why people survive hour-long drowning accidents in winter but not in summer, how certain plants generate heat (the skunk cabbage enough to melt snow around it). We also hear of systems gone awry--how desert species given too much water can drink themselves into bloated immobility, why anorexics often complain of feeling cold, and why you can't sleep if the room is too hot or too cold. After reading this book, you'll never look at a thermostat in quite the same way again. Table of Contents: Introduction 1. Temperature: A User's Guide 2. Behave Yourself 3. Then Bake at 98.6°F for 400,000 Minutes 4. Everything in Its Place 5. Cold New World 6. Fever All through the Night 7. The Heat of Passion 8. Livin' off the Fat 9. The Light Goes Out Epilogue Bibliography Acknowledgments Index Reviews of this book: There's a little twinkle in Mark Blumberg's eye as he explains the role of temperature in life on Earth, that essential gleam that makes books about science successful and appealing...His writing is clear, a fine balance of explanation, example and ideas. --Susan Salter Reynolds, Los Angeles Times Book Review Reviews of this book: The need to maintain body temperature within a narrow range is the biggest single influence on physiology and behaviour, as Mark Blumberg explains in this little gem of a book, Body Heat...Blumberg describes the exquisite mechanisms developed by different species to generate, conserve or lose body heat. --John Bonner, New Scientist Reviews of this book: This is one of those books that leaves you for a few heady days in possession of a new key to all mysteries. Written entertainingly for a popular audience, the book argues that the evolved behaviour and physical characteristics of most creatures, from the tiniest nematode worm to the largest whale, is governed by the need to maintain a comfortable body temperature. --Emma Crichton-Miller, The Telegraph Reviews of this book: Blumberg...presents a thoroughly interesting book on body temperature and its many influences, loaded with a marvelously broad range of topics related to the biology of body temperature. From structural adaptations, such as ear size, circulatory patterns, and body shape that have evolved to help maintain body temperature, to psychological effects of temperature, the physiology of fevers, and even sexual-thermal metaphors used in everyday conversation. A host of fascinating aspects of how species respond to temperature changes are also discussed...Body Heat is great reading, certain to produce an enlightened appreciation for how body temperature control is critical for all organisms. --M. A. Palladino, Choice Reviews of this book: Mark S. Blumberg, in Body Heat, also takes the role of temperature in human affairs onto a global stage, but his metaphors, languages and conclusions are neither biblical nor prophetic. Instead he wants to remind us just how narrow our margins of tolerance are against that ultimate enemy: cold...Blumberg loves his subject, is convinced of its importance, and he wants to put across the intrinsic interest of temperature physiology to a larger audience. He retains a light touch--and because he is an active researcher in his own right, is able to bring new information and new insights to his pages. --Jonathan Kingdon, Times Literary Supplement This book is a real treat. Mark Blumberg takes something we normally hardly think about, and makes it into a fascinating topic, with colorful examples from fields as disparate as etymology and entomology. You probably will be repeating many of the stories he tells to those around you, as you discover why a fever may be good for you, or how babies generate their own heat, or how eating disorders interact with body temperature problems. It's entertaining, interesting, and great fun. --Michael Leon, University of California, Irvine This is an engaging enchilada of a book, wrapping up cold feet, a warm heart, hot sex, and chili peppers, for easy digestion by the general science consumer. Delicious! --Bernd Heinrich, University of Vermont, and author of The Hot-Blooded Insects: Strategies and Mechanisms of Thermoregulation
Brain Facts is a primer on the brain and nervous system, published by the Society for Neuroscience. Brain Facts is a valuable resource for educators, students, and anyone interesting in learning about neuroscience. Download an audio recording of Brain Facts today, available on BrainFacts.org and through iTunes U. The brain is the most complex biological structure in the known universe. It is a topic rich with exciting new discoveries, continuing profound unknowns, and critical implications for individuals, families, and societies. Learn more about the brain and nervous system through articles, images, videos, and more on BrainFacts.org, a public information initiative of The Kavli Foundation, the Gatsby Charitable Foundation, and the Society for Neuroscience.
Over the last decades, our understanding of the relationship between thermoregulation, performance and fatigue has changed dramatically. New advances in technology and methodology permitted the study of rising and decreasing body temperature on metabolism and provided insights into the role the nervous system plays in determining human performance under thermally stressful situations. Further analysis of previous research has been necessary in addition to considering theories derived from complimentary areas of research such as evolutionary biology, anthropology and cellular and molecular biology. This publication provides different interpretations of recent research for a better understanding of the limitations of thermoregulation. In particular, it presents evidence for the human's ability to anticipate thermal limits and adjust their performance accordingly so that cellular homeostasis is preserved. Further, the book is featuring the inclusion of the effect of reduced body temperature on muscular performance and endurance which today is a popular method for providing avenues of reduced thermal strain and recovery from exercise. This publication will be an essential read for those working in thermal medicine, exercise physiology and human performance.
