A biosensor is a detecting device that combines a transducer with a biologically sensitive and selective component. Biosensors can measure compounds present in the environment, chemical processes, food and human body at low cost if compared with traditional analytical techniques. This book covers a wide range of aspects and issues related to biosensor technology, bringing together researchers from 16 different countries. The book consists of 24 chapters written by 76 authors and divided in three sections: Biosensors Technology and Materials, Biosensors for Health and Biosensors for Environment and Biosecurity.
Biomarkers in Environmental and Human Health Biomonitoring: An Integrated Perspective provides a holistic view of the biomonitoring of environmental degradation, accumulated toxicity, and associated human health concerns. The book incorporates theoretical and practical aspects of the biomonitoring of environmental pollution and the health surveillance of ecological communities using samples from living organisms which are analyzed for contaminants and toxin levels. In the first half, the book provides a general overview if the different types of biomarkers, their significance as bioindicators for contaminants and detection of toxicity, as well as how they can be utilized in the restoration of degraded ecosystems. The second half of the book discusses molecular biomarkers and how they are used as diagnostic and prognostic tools for pollution monitoring. It also reviews analytical tools used to validate the biomarkers in the detection and monitoring of pollution and disease. Finally, the book delves into how novel approaches like genetic ecotoxicology; Big Data, and artificial intelligence calculates the potential consequences of environmental pollution on the ecosystems and on human health. - Covers the fundamentals, types, significance, and limitations of biomarkers - Examines various types of plants, animals, and secondary metabolites in identifying and monitoring toxicity in different ecosystems and potential impacts on health - Reviews biomarker-based and bioinformatic tools in the detection and monitoring of environmental pollution and associated human health
This book is a collection of contributions from leading specialists on the topic of biosensors for health, environment and biosecurity. It is divided into three sections with headings of current trends and developments; materials design and developments; and detection and monitoring. In the section on current trends and developments, topics such as biosensor applications for environmental and water monitoring, agro-industry applications, and trends in the detection of nerve agents and pesticides are discussed. The section on materials design and developments deals with topics on new materials for biosensor construction, polymer-based microsystems, silicon and silicon-related surfaces for biosensor applications, including hybrid film biosensor systems. Finally, in the detection and monitoring section, the specific topics covered deal with enzyme-based biosensors for phenol detection, ultra-sensitive fluorescence sensors, the determination of biochemical oxygen demand, and sensors for pharmaceutical and environmental analysis.
Clinical Correlation and Diagnosis highlights the improvements in methodological approaches for the purposes of disease diagnosis and health research. Chapters cover such topics as serum protein electrophoresis, urinary iodine measurement, blood collection tubes, semi-solid phase assay and advancement in analytical and bioanalytical techniques, and serological diagnostic tools for Zika virus, among other subjects. All these will not be possible without a proper laboratory management where this book also includes the Tissue Bank ATMP Production as a model. The chapters are expected to provide a new perspective in health science which may trigger a further exploration into the diagnostic and research field.
Advanced materials and nanotechnology is a promising, emerging field involving the use of nanoparticles to facilitate the detection of various physical and chemical parameters, including temperature, humidity, pH, metal ion, anion, small organic or inorganic molecules, gases, and biomolecules responsible for environmental issues that can lead to diseases like cancer, diabetes, osteoarthritis, bacterial infections, and brain, retinal, and cardiovascular diseases. By monitoring environmental samples and detecting these environmental issues, advanced nanotechnology in this type of sensory technology is able to improve daily quality of life. Although these sensors are commercially available for the detection of monovalent cations, anions, gases, volatile organic molecules, heavy metal ions, and toxic metal ions, many existing models require significant power and lack advanced technology for more quality selectivity and sensitivity. There is room in these sensors to optimize their selectivity, reversibility, on/off ratio, response time, and their environmental stability in real-world operating conditions. This book explores the methods for the development and design of environmentally-friendly, simple, reliable, and cost effective electrochemical nanosensors using powerful nanostructured materials. More specifically, it highlights the use of various electrochemical-based biosensor sensors involved in the detection of monovalent cations, anions, gases, volatile organic molecules, heavy metal ions, and toxic metal ions, with the ultimate goal of seeing these technologies reach market.
This book focusses on recent advances and different research issues in the biosensor technology and also presents theoretical, methodological, well-established and validated empirical work dealing with the technology. The book addresses challenges for the development of a point-of-care test platform. The book also describes printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive, multiplex detection of disease biomarkers in real samples. It aims to overcome existing barriers for Lab-on-a-Chip commercialization (lack of cost effective mass manufacturing methods, self-contained, fully autonomous operation and user-friendliness). Different advanced techniques including electrochemical, optical, mass, colorimetric and signal amplification strategies describe early stage disease diagnosis. The book gathers scientific and technological novelties and advancements already developed or under development in the academic and research communities. It covers a vast audience from basic science to engineering and technology experts and learners.
Biosensors are poised to make a large impact in environmental, food, and biomedical applications, as they clearly offer advantages over standard analytical methods, including minimal sample preparation and handling, real-time detection, rapid detection of analytes, and the ability to be used by non-skilled personnel. Covering numerous applications of biosensors used in food and the environment, Portable Biosensing of Food Toxicants and Environmental Pollutants presents basic knowledge on biosensor technology at a postgraduate level and explores the latest advances in chemical sensor technology for researchers. By providing useful, state-of-the-art information on recent developments in biosensing devices, the book offers both newcomers and experts a roadmap to this technology. In the book, distinguished researchers from around the world show how portable and handheld nanosensors, such as dynamic DNA and protein arrays, enable rapid and accurate detection of environmental pollutants and pathogens. The book first introduces the basic principles of biosensing for newcomers to the technology. It then explains how the integration of a "receptor" can provide analytically useful information. It also describes trends in biosensing and examines how a small-sized device can have portability for the in situ determination of toxicants. The book concludes with several examples illustrating how to determine toxicants in food and environmental samples.
Commercial Biosensors and Their Applications: Clinical, Food, and Beyond offers professionals an in-depth look at some of the most significant applications of commercially available biosensor-based instrumentation in the clinical, food quality control, bioprocess monitoring, and bio threat fields. Featuring contributions by an international team of scientists, this book provides readers with an unparalleled opportunity to see how their colleagues around the world are using these powerful tools. This book is an indispensable addition to the reference libraries of biosensor technologists, analytical chemists, clinical chemists, biochemists, physicians, medical doctors, engineers, and clinical biochemists. The book discusses the need for portable, rapid, and smart biosensing devices and their use as cost-effective, in situ, real-time analytical tools in a variety of fields. - Devotes several chapters to applications of biosensors to clinical samples, exploring how biosensors are currently used for in-home diabetes monitoring, point-of-care diagnostics, non-invasive sensing, and biomedical research - Includes a section on food applications covering how biosensors can detect genetically modified organisms, toxins, allergens, hormones, microorganisms, species-specificity, pesticides, insecticides, and related components - Discusses nanobiosensor and applications, including a chapter on nanotechnological approaches and materials in commercial biosensors
With the support of this comprehensive guide, discover the world of cutting-edge biosensing technological advancements. Prominent specialists explore the theoretical underpinnings and real-world applications of wearable sensors, solid-state sensors, electrochemical sensors, microfluidic sensors, and nanostructures-based sensors. Regardless of your background - scientist, academic, student, or professional - this book gives you the tools to advance biosensor technology. Come along on this journey with us toward a healthier, cleaner future where biosensors are essential to creating a better world.
This book offers comprehensive coverage of biomarker/biosensor interactions for the rapid detection of weapons of bioterrorism, as well as current research trends and future developments and applications. It will be useful to researchers in this field who are interested in new developments in the early detection of such. The authors have collected very valuable and, in some aspects indispensable experience in the area i.e. in the development and application of portable biosensors for the detection of potential hazards. Most efforts are centered on the development of immunochemical assays including flow-lateral systems and engineered antibodies and their fragments. In addition, new approaches to the detection of enzyme inhibitors, direct enzymatic and microbial detection of metabolites and nutrients are elaborated. Some realized prototypes and concept devices applicable for the further use as a basis for the cooperation programs are also discussed.There is a particular focus on electrochemical and optical detection systems,including those employing carbon nanotubes, quantum dots and metalnanoparticles. The authors are well-known scientists and most of them are editors of respected international scientific journals. Although recently developed biosensors utilize known principles, the biosensing devices described can significantly shorten the time required for successful detection and enhance efforts in more time-consuming directions, e.g. remote sensing systems and validation in real-sample analysis.The authors describe advances in all stages of biosensor development: theselection of biochemical components, their use in biosensor assembly, detection principles and improvements and applications for real sample assays.
