Biomedical Applications of Microprobe Analysis
Biomedical Applications of Microprobe Analysis

Author: Peter Ingram

Publisher: Academic Press

Published: 1999-10-29

Total Pages: 573

ISBN-13: 0080524567

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Biomedical Applications of Microprobe Analysis is a combination reference/laboratory manual for the use of microprobe analysis in both clinical diagnostic and research settings. Also called microchemical microscopy, microprobe analysis uses high-energy bombardment of cells and tissue, in combination with high resolution EM or confocal microscopy to provide a profile of the ion, metal, and mineral concentrations present in a sample. This allows insight into the physiology and pathophysiology of a wide variety of cells and tissues.This book describes methods for obtaining detailed information about the identity and composition of particles too small to be seen with the naked eye and describes how this information can be useful in diagnostic and biomedical research. - Up-to-date review of electron microprobe analysis - Detailed descriptions of sample preparation techniques - Recent technologies including confocal microscopy, infrared microspectroscopy, and laser raman spectroscopy - Over 100 illustrations with numerous specific applications - Contributions by world-renowned experts in the field - Brief summary of highlights precedes each chapter

Techniques In Microscopy For Biomedical Applications
Techniques In Microscopy For Biomedical Applications

Author: Terje Dokland

Publisher: World Scientific Publishing Company

Published: 2006-09-28

Total Pages: 422

ISBN-13: 9813101954

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The second volume of the series Manuals in Biomedical Research, this book is aimed to be both a concise introduction to the diverse field of microscopy and a practical guide those who require the use of microscopic for methods in their research. It provides young as well as experienced scientists a state-of-the-art multidisciplinary overview of microscopic techniques, covering all the major microscopy fields in biomedical sciences and showing their application in evaluating samples ranging from molecules to cells and tissues.Microscopy has revolutionized our understanding of biological events. Within the last two decades, microscopic techniques have provided insights into the dynamics of biological processes that regulate such events. Biological discovery, to a large extent, depends on advances in imaging techniques and various microscopic techniques have emerged as central and indispensable tools in the biomedical sciences.The four authors bring with them extensive experiences spanning across disciplines such as Microbiology, Molecular and Cell Biology, Tissue Engineering, Biomedical and Regenerative Medicine and so forth, reinforcing the fact that microscopy has proven useful in countless investigations into the mysteries of life.

Handbook of Sample Preparation for Scanning Electron Microscopy and X-Ray Microanalysis
Handbook of Sample Preparation for Scanning Electron Microscopy and X-Ray Microanalysis

Author: Patrick Echlin

Publisher: Springer Science & Business Media

Published: 2011-04-14

Total Pages: 329

ISBN-13: 0387857311

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Scanning electr on microscopy (SEM) and x-ray microanalysis can produce magnified images and in situ chemical information from virtually any type of specimen. The two instruments generally operate in a high vacuum and a very dry environment in order to produce the high energy beam of electrons needed for imaging and analysis. With a few notable exceptions, most specimens destined for study in the SEM are poor conductors and composed of beam sensitive light elements containing variable amounts of water. In the SEM, the imaging system depends on the specimen being sufficiently electrically conductive to ensure that the bulk of the incoming electrons go to ground. The formation of the image depends on collecting the different signals that are scattered as a consequence of the high energy beam interacting with the sample. Backscattered electrons and secondary electrons are generated within the primary beam-sample interactive volume and are the two principal signals used to form images. The backscattered electron coefficient ( ? ) increases with increasing atomic number of the specimen, whereas the secondary electron coefficient ( ? ) is relatively insensitive to atomic number. This fundamental diff- ence in the two signals can have an important effect on the way samples may need to be prepared. The analytical system depends on collecting the x-ray photons that are generated within the sample as a consequence of interaction with the same high energy beam of primary electrons used to produce images.

Introduction to BioMEMS
Introduction to BioMEMS

Author: Albert Folch

Publisher: CRC Press

Published: 2016-04-19

Total Pages: 528

ISBN-13: 1466509384

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The entire scope of the BioMEMS field-at your fingertipsHelping to educate the new generation of engineers and biologists, Introduction to BioMEMS explains how certain problems in biology and medicine benefit from and often require the miniaturization of devices. The book covers the whole breadth of this dynamic field, including classical microfabr

Titanium-Based Alloys for Biomedical Applications
Titanium-Based Alloys for Biomedical Applications

Author: Petrică Vizureanu

Publisher: Materials Research Forum LLC

Published: 2020-06-05

Total Pages: 161

ISBN-13: 1644900793

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The book presents the state-of-the-art of biomaterials used in the human body and reports new research on various Ti-based alloys with non-toxic elements (Mo, Zr, Ta, Si, Nb, etc.) aimed at improved mechanical properties, corrosion resistance and biocompatibility. Specific laboratory tests are reported for structural characterization, mechanical properties and corrosion resistance testing, and cytotoxicity assessment. Keywords: Titanium Alloys, Biomedical Materials, Cytotoxicity Assessment, Biocompatibility, Production and Properties of Ti-Mo-Zr-Ta Alloys, Surface Modification, Powder Metallurgy, Characterization of Ti-Mo-Zr-Ta-Alloys, Mechanical Properties, Differential Scanning Calorimetry, Electrochemical Behavior, Optical Microstructure, X-ray Diffraction, Thermal Characterization, Corrosion Resistance, Medical Applications.

Nanocoatings Nanosystems Nanotechnologies
Nanocoatings Nanosystems Nanotechnologies

Author: Alexander D. Pogrebnjak

Publisher: Bentham Science Publishers

Published: 2012-09-17

Total Pages: 159

ISBN-13: 1608054160

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This Reference eBook deals with an existing classification of a nanosized structure and an analysis of its properties. It summarizes an information about how a grain size affects physical, mechanical, thermal, and other properties of a nanostructured material. A basic method, which is employed for a fabrication of an isolated nanoparticle, an ultradisperse powder, a compact nanocystalline, nanoporous, and amorphous material, a fullerene, a nanotube, and a nanostuctured coating, is considered. Investigation methods, which are applied to study the nanostructured material, are briefly described. A modern understanding of a formation of the nanostructured and nanocomposite coating, which are fabricated using a ion-plasma deposition method, is reposted. A potential application of the nanostructured material and coating in a field of engineering is demonstrated. Readership: Graduate, Postgraduate, Ph.D. Students, Researchers and Industry Professionals. The eBook contains 9 Chapters, 87 Figures, 14 Tables, 411 References-totally, 155 Pages. It was approved by two Scientific Boards from National Kharkov University and Sumy State University. A main content of this eBook is a basis for lectures presented for students at Sumy State University (the Physical-Technical Faculty), Kharkov National University (the Physical Faculty), Omsk State University (the Physical Faculty, the Department of Material Science), East-Kazakhstan State Technical University (Ust-Kamenogorsk, Kazakhstan), and Moscow State University (the Physical Faculty, Moscow, Russia). A source of this eBook is original papers of leading world-known scientists, who ware involved in a field of new nano composite material fabrication, nanotechnologies, and researches. This version had not been published elsewhere. It is interesting for a wide circle of specialists, Masters, aspirants, scientific researchers, and a technical staff of Higher Education System, Research Institutes and Laboratories. It covers recent data since 2008 to 2010 year.

Biological Field Emission Scanning Electron Microscopy
Biological Field Emission Scanning Electron Microscopy

Author: Roland A. Fleck

Publisher: John Wiley & Sons

Published: 2019-02-06

Total Pages: 720

ISBN-13: 1118663241

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The go‐to resource for microscopists on biological applications of field emission gun scanning electron microscopy (FEGSEM) The evolution of scanning electron microscopy technologies and capability over the past few years has revolutionized the biological imaging capabilities of the microscope—giving it the capability to examine surface structures of cellular membranes to reveal the organization of individual proteins across a membrane bilayer and the arrangement of cell cytoskeleton at a nm scale. Most notable are their improvements for field emission scanning electron microscopy (FEGSEM), which when combined with cryo-preparation techniques, has provided insight into a wide range of biological questions including the functionality of bacteria and viruses. This full-colour, must-have book for microscopists traces the development of the biological field emission scanning electron microscopy (FEGSEM) and highlights its current value in biological research as well as its future worth. Biological Field Emission Scanning Electron Microscopy highlights the present capability of the technique and informs the wider biological science community of its application in basic biological research. Starting with the theory and history of FEGSEM, the book offers chapters covering: operation (strengths and weakness, sample selection, handling, limitations, and preparation); Commercial developments and principals from the major FEGSEM manufacturers (Thermo Scientific, JEOL, HITACHI, ZEISS, Tescan); technical developments essential to bioFEGSEM; cryobio FEGSEM; cryo-FIB; FEGSEM digital-tomography; array tomography; public health research; mammalian cells and tissues; digital challenges (image collection, storage, and automated data analysis); and more. Examines the creation of the biological field emission gun scanning electron microscopy (FEGSEM) and discusses its benefits to the biological research community and future value Provides insight into the design and development philosophy behind current instrument manufacturers Covers sample handling, applications, and key supporting techniques Focuses on the biological applications of field emission gun scanning electron microscopy (FEGSEM), covering both plant and animal research Presented in full colour An important part of the Wiley-Royal Microscopical Series, Biological Field Emission Scanning Electron Microscopy is an ideal general resource for experienced academic and industrial users of electron microscopy—specifically, those with a need to understand the application, limitations, and strengths of FEGSEM.

Advances and Challenges in Pharmaceutical Technology
Advances and Challenges in Pharmaceutical Technology

Author: Amit Kumar Nayak

Publisher: Academic Press

Published: 2021-02-09

Total Pages: 572

ISBN-13: 0128203005

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Advances and Challenges in Pharmaceutical Technology: Materials, Process Development and Drug Delivery Strategies examines recent advancements in pharmaceutical technology. The book discusses common formulation strategies, including the use of tools for statistical formulation optimization, Quality by design (QbD), process analytical technology, and the uses of various pharmaceutical biomaterials, including natural polymers, synthetic polymers, modified natural polymers, bioceramics, and other bioinorganics. In addition, the book covers rapid advancements in the field by providing a thorough understanding of pharmaceutical processes, formulation developments, explorations, and exploitation of various pharmaceutical biomaterials to formulate pharmaceutical dosage forms. - Provides extensive information and analysis on recent advancements in the field of pharmaceutical technology - Includes contributions from global leaders and experts in academia, industry and regulatory agencies - Uses high quality illustrations, flow charts and tables to explain concepts and text to readers, along with practical examples and research case studies

Microbeam Analysis in Biology
Microbeam Analysis in Biology

Author: Claude Lechene

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 695

ISBN-13: 0323143342

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Microbeam Analysis in Biology contains the proceedings of a workshop on Biological X-Ray Microanalysis by Electron Beam Excitation, held in Boston, Massachusetts on August 25-26, 1977. This book focuses on the principles, techniques, and biological use of electron probe microanalysis, energy-loss spectroscopy, and ion probe microanalysis. This text reflects the emphasis of the workshop on presenting the principles of analysis, the optimization of operating conditions, the description of successful techniques for sample preparation and quantitation, the illustration of problems and pitfalls, and the direction of microbeam analysis in biology.