Waisted: The Biology of Body Fat

Waisted: The Biology of Body Fat

Author: Nathan Denton

Publisher: Oxford University Press

Published: 2022-01-06

Total Pages: 305

ISBN-13: 0192634577

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Waisted: The Biology of Body Fat outlines the fascinating, often misunderstood and sometimes controversial biology of fat, otherwise known as adipose tissue. It provides a comprehensive, evidence-based perspective on fat biology and its crucial role in human evolution, health, disease, and society. The content draws upon biomedical, epidemiological, social and evolutionary research to understand the striking relationship between body fat distribution and health outcomes. Using digestible analogies, real-world examples and images, it highlights the multi-faceted relationship between adipose biology and society. Waisted clearly conveys the key concepts and assumptions that can lead to negative perceptions of fat, and reframes these challenges to highlight the underappreciated importance of adipose tissue in humans. Waisted is an accessible yet in-depth exploration of the subject that is suitable for both specialists and non-specialists alike. It is a highly valuable resource for clinicians, health practitioners, biomedical researchers, and students who study adipose biology, obesity, and diseases related to fat dysfunction. This book also provides an interesting sociological and anthropological read for anyone who wants to gain a broader and deeper appreciation of the unique role that adipose tissue plays in human evolution and society, by considering how biological and social factors intersect.


Adipose Tissue Biology

Adipose Tissue Biology

Author: Michael E. Symonds

Publisher: Springer Science & Business Media

Published: 2011-11-20

Total Pages: 414

ISBN-13: 1461409659

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This book is designed to provide a comprehensive insight into current perspectives and challenges in adipose tissue biology. In Adipose Tissue Biology, scientists and clinicians discuss adipocyte precursors, differentiation and growth, brown and white adipose tissue, gender, inflammation, dietary and genetic determinants of fat mass, together with evolutionary and developmental aspects of adiposity.


Adipocyte Biology and Hormone Signaling

Adipocyte Biology and Hormone Signaling

Author: James M. Ntambi

Publisher:

Published: 2000

Total Pages: 256

ISBN-13:

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This text emphasizes the molecular regulation of lipid biogenesis in the context of adipocyte metabolism, differentiation, gene expression, hormone and growth signaling. Many disciplines such as genetics, cell biology and biochemistry are merging to provide a more detailed understanding of the dyamnic role that the fat cell plays in metabolism, disease and signaling.


Adipocytes

Adipocytes

Author: Michelle J. Weber

Publisher:

Published: 2013

Total Pages: 0

ISBN-13: 9781620815373

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Adipose tissue has an important regulatory role in mammalian metabolism by storing and releasing high-energy metabolites according to the body energy needs, whether by storing excess energy in the form of triglycerides (TG), or by breaking down TG into fatty acids (FA) and glycerol. In this book, the authors present topical research in the study of the biology, regulation and health impacts of adipocytes. Topics discussed include the development, differentiation, structure and function of each type of adipose tissue in association with chronic diseases, such as obesity and insulin resistance; mTOR and regulation of adipose tissue metabolism and perfusion; adipose tissue-derived microvesicles and exosomes and the diagnosis of metabolic diseases; early regulation of adipogenesis; calpain-mediated regulation of bone and fat mass and glucose homeostasis in osteoblasts; and the role of estrogen-related receptors in adipocyte differentiation.


Adipose Tissue Biology

Adipose Tissue Biology

Author: Michael E. Symonds

Publisher: Springer

Published: 2017-04-03

Total Pages: 459

ISBN-13: 3319520318

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The past decade has seen an exponential increase in our knowledge and understanding of adipose tissue biology. This has coincided with the continued rise in obesity across all generations. Clearly despite substantial advances in research into adipose tissue this still has had limited impact on the on-going obesity epidemic across a majority of countries in the world. This book brings together many leading experts in the field to provide an up to date and comprehensive review of the key aspects of adipose tissue. It therefore includes chapters on evolution, development and inflammation together with a detailed review of brown and beige adipose tissue biology and their potential significance in preventing or combating obesity. These chapters are complemented by those on genetics and gender influences, together with nutrition through the life cycle. Ultimately the book provides an overview of the complexities of adipose tissue biology and the continuing challenge to combat obesity in the 21st century.


Novel Insights into Adipose Cell Functions

Novel Insights into Adipose Cell Functions

Author: Karine Clément

Publisher: Springer Science & Business Media

Published: 2010-09-14

Total Pages: 154

ISBN-13: 364213517X

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Obesity is a disease of society and economic transition spreading at an epidemic pace throughout the world. According to the World Health Organization, obesity is defined as an increased or abnormal accumulation of body fat mass to the extent that individual’s health will be negatively affected. Overweight is thus being considered as top at risk condition in the world and it is mandatory to identify the physiopathological causes involved in adipose tissue enlargement and related metabolic and cardiovascular health disorders.This volume provides the most up to date insights into the biology of a complex endocrine organ: the adipose tissue.


Brown Adipose Tissue

Brown Adipose Tissue

Author: David A. Guertin

Publisher: Springer Nature

Published: 2022-02-15

Total Pages: 319

ISBN-13: 1071620878

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This detailed volume explores techniques for researching brown adipose tissue (BAT) and the fascinating biology and therapeutic potential of thermogenic adipocytes. The content reflects the advancing technologies in genetics, imaging, and 'omics strategies that are allowing researchers to probe BAT biology at unprecedented depths and detail, yet it also presents classic physiology principles, which remain the core tenets of BAT biology. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Brown Adipose Tissue: Methods and Protocols provides perspectives and detailed protocols for the benefit of both new BAT researchers looking for guidance as well as seasoned researchers who would like to expand their toolkits. Chapter 12 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.


Methods of Adipose Tissue Biology Part B

Methods of Adipose Tissue Biology Part B

Author:

Publisher: Academic Press

Published: 2014-02-11

Total Pages: 357

ISBN-13: 0128003367

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This book is a must-have for anyone interested in obesity or the physiology of white or brown adipose tissues. It contains state-of-the-art methods from researchers that are world leaders in this field. Detailed lab protocols range from methods to visualize adipocytes and adipose tissues in humans and experimental models, to convert stem cells into white and brown adipocytes in vitro, to evaluate aspects of adipocyte metabolism, to inducibly knock out genes in adipose tissues, and to evaluate transcriptional control of adipogenesis on a global scale. The study of adipose tissue goes hand in hand with our global effort to understand and reverse the epidemic of obesity and associated medical complications Contributors include leading researchers who have made tremendous contributions to our ability to investigate white and brown adipose tissues The wide variety of experimental approaches detailed within this volume: including the evaluation of adipose tissue biology at the molecular, biochemical, cellular, tissue, and organismal levels


Methods of Adipose Tissue Biology Part A

Methods of Adipose Tissue Biology Part A

Author:

Publisher: Academic Press

Published: 2014-01-27

Total Pages: 397

ISBN-13: 012411606X

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Methods of Adipose Tissue Biology is a must-have for anyone interested in obesity or the physiology of white or brown adipose tissues. It contains state-of-the-art methods from researchers who are world leaders in this field. Detailed lab protocols include methods to visualize adipocytes and adipose tissues in humans and experimental models, converting stem cells into white and brown adipocytes in vitro, evaluating aspects of adipocyte metabolism, inducibly knocking out genes in adipose tissues, and evaluating transcriptional control of adipogenesis on a global scale. The study of adipose tissue goes hand in hand with our global effort to understand and reverse the epidemic of obesity and associated medical complications Contributors include leading researchers who have made tremendous contributions to our ability to investigate white and brown adipose tissues The wide variety of experimental approaches detailed within this volume: including the evaluation of adipose tissue biology at the molecular, biochemical, cellular, tissue, and organismal levels