Bioengineering and Biomaterials in Ventricular Assist Devices
Bioengineering and Biomaterials in Ventricular Assist Devices

Author: Eduardo Guy Perpétuo Bock

Publisher: CRC Press

Published: 2021-10-07

Total Pages: 350

ISBN-13: 1000462897

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Often associated with artificial hearts, ventricular assist devices (VADs) are blood pumps that can provide circulatory assistance to the left ventricle, the right ventricle, or both. Bioengineering and Biomaterials in Ventricular Assist Devices reviews constructive details of VADs and the biomaterials used in their development and support. FEATURES Establishes an area of intersection between engineering and medicine Shows process development from mechanical design to automation and control Discusses biofunctional materials, tribology in ceramic biomaterials, biosensors, and surface engineering and blood This text is aimed at advanced students, researchers, and practicing engineers conducting work on VADs and will be of interest to a broad interdisciplinary group, including bioengineers, materials engineers, chemical engineers, mechanical engineers, and electrical engineers.

Biomedical Devices and Their Applications
Biomedical Devices and Their Applications

Author: D. Shi

Publisher: Springer

Published: 2010-12-09

Total Pages: 201

ISBN-13: 9783642060687

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Biomedical devices that contact with blood or tissue represent a wide range of products. Depending on their potential harm to a body, medical devices are categorized according to the degree, so their safety can be assured. All biomaterials are by definition designed to contact with a body for a certain period of time. The nature of the body contact, as well as the duration a material contacts with the body may initiate unwanted biological In comparison with invasive devices Oike catheters and medical responses. implants contact directly with tissue or with the circulating blood) non invasive devices (like wound-dressings and contact lenses contact with the skin, the sclera, and the mucosa or with open wounds) have a lesser risk of hurting a patient. When blood contacts with a foreign material, plasma proteins become absorpted to the surface within a few seconds. The reactions that follow, the so-called intrinsic pathway lead to the formation of fibrin and activation of platelets and white blood cells, result in blood clot formation.

Biomedical Devices and Their Application
Biomedical Devices and Their Application

Author:

Publisher: 清华大学出版社有限公司

Published: 2004

Total Pages: 234

ISBN-13: 9787302060543

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本书共有5 章,分别是:药品运送中的生物材料、对现有的药品运输类型及其在治疗局部病变的临床作用、蛋白质电泳技术及其应用、模拟雌激素的化学药品以及生物技术在医学工程中的应用。

Biomaterials for Artificial Organs
Biomaterials for Artificial Organs

Author: Michael Lysaght

Publisher: Elsevier

Published: 2010-12-20

Total Pages: 313

ISBN-13: 0857090844

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The worldwide demand for organ transplants far exceeds available donor organs. Consequently some patients die whilst waiting for a transplant. Synthetic alternatives are therefore imperative to improve the quality of, and in some cases, save people’s lives. Advances in biomaterials have generated a range of materials and devices for use either outside the body or through implantation to replace or assist functions which may have been lost through disease or injury. Biomaterials for artificial organs reviews the latest developments in biomaterials and investigates how they can be used to improve the quality and efficiency of artificial organs.Part one discusses commodity biomaterials including membranes for oxygenators and plasmafilters, titanium and cobalt chromium alloys for hips and knees, polymeric joint-bearing surfaces for total joint replacements, biomaterials for pacemakers, defibrillators and neurostimulators and mechanical and bioprosthetic heart valves. Part two goes on to investigate advanced and next generation biomaterials including small intestinal submucosa and other decullarized matrix biomaterials for tissue repair, new ceramics and composites for joint replacement surgery, biomaterials for improving the blood and tissue compatibility of total artificial hearts (TAH) and ventricular assist devices (VAD), nanostructured biomaterials for artificial tissues and organs and matrices for tissue engineering and regenerative medicine.With its distinguished editors and international team of contributors Biomaterials for artificial organs is an invaluable resource to researchers, scientists and academics concerned with the advancement of artificial organs. Reviews the latest developments in biomaterials and investigates how they can be used to improve the quality and efficiency of artificial organs Discusses commodity biomaterials including membranes for oxygenators and cobalt chromium alloys for hips and knees and polymeric joint-bearing surfaces for total joint replacements Further biomaterials utilised in pacemakers, defibrillators, neurostimulators and mechanical and bioprosthetic heart valve are also explored

Encyclopedia of Biomaterials and Biomedical Engineering
Encyclopedia of Biomaterials and Biomedical Engineering

Author: Gary Wnek

Publisher: CRC Press

Published: 2008-05-28

Total Pages: 3145

ISBN-13: 1498761437

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Written by more than 400 subject experts representing diverse academic and applied domains, this multidisciplinary resource surveys the vanguard of biomaterials and biomedical engineering technologies utilizing biomaterials that lead to quality-of-life improvements. Building on traditional engineering principles, it serves to bridge advances in materials science, life sciences, nanotechnology, and cell biology to innovations in solving medical problems with applications in tissue engineering, prosthetics, drug delivery, biosensors, and medical devices. In nearly 300 entries, this four-volume Encyclopedia of Biomaterials and Biomedical Engineering, Second Edition, covers: essential topics integral to tissue engineering research: bioreactors, scaffolding materials and fabrication, tissue mechanics, cellular interaction, and development of major tissues and organs being attempted by researchers worldwide; artificial lungs and muscles, bio-artificial livers, and corneal, dental, inner ear, and total hip implants; tissue engineering of blood vessels, heart valves, ligaments, microvascular networks, skeletal muscle, and skin; bone remodeling, bone cement, and bioabsorbable bone plates and screws; controlled drug delivery, insulin delivery, and transdermal and ocular implant-based drug delivery; endovascular stent grafts, vascular grafts, and xenografts; 3-D medical imaging, electrical impedance imaging, and intravascular ultrasound; biomedical, protein adsorption, and in vivo cardiovascular modeling; polymer foams, biofunctional and conductive polymers, and electroactive polymeric materials; blood–material interactions, the bone–implant interface, host reactions, and foreign body responses and much more.

Biomaterials
Biomaterials

Author: L. Stark

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 283

ISBN-13: 1461565553

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Essentially three groups of research workers are con cerned with biomaterials. The biophysicists, the biochemists and some bioengineers (particularly the metallurgists) are engaged in a study of the basic properties of engineering materials suitable for medical use and of biological mate rials. The bioengineers in general as part of a team are engaged in developing new devices suitable for medical pur poses including implantable devices; spectacular examples of such devices are artificial kidney and mechanical heart. The medical people, dentists, surgeons and others, play an impor tant role in developing criterions for the biomaterials, in the eValuation of such materials in physiological environment and as consumers of biomaterials. This workshop was an effort to bring together representatives of the above groups to ex change experiences and viewpoints in regard to both research and training in this rapidly developing and vital area. The individual presentations are some typical examples of biomaterials research. There are numerous other examples but basically they fall into three categories: materials in medicine, biological materials, and semi-artificial materials derived from biological sources. As a whole, the book pro vides a comprehensive but not exhaustive picture of the present state of affairs in the field of biomaterials. To the educators the discussion on training should be of par ticular interest. Those concerned with scientific adminis trations and policy would find the section on the interaction between government, industry and university very valuable.

Biomedical Devices
Biomedical Devices

Author: Raymond H. W. Lam

Publisher: Springer

Published: 2019-08-16

Total Pages: 379

ISBN-13: 3030242374

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This textbook provides essential knowledge for biomedical product development, including material properties, fabrication processes and design techniques for different applications, as well as process design and optimization. This book is multidisciplinary and readers can learn techniques to apply acquired knowledge for various applications of biomedical design. Further, this book encourages readers to discover and convert newly reported technologies into products and services for the future development of biomedical applications. This is an ideal book for upper-level undergraduate and graduate students, engineers, technologists, and researchers working in the area of biomedical engineering and manufacturing. This book also: Provides a comprehensive set of fundamental knowledge for engineering students and entry level engineers to design biomedical devices Offers a unique approach to manufacturing of biomedical devices by integrating and formulating different considerations in process design tasks into optimization problems Provides a broad range of application examples to guide readers through the thinking process of designing and manufacturing biomedical devices, from basic understanding about the requirements and regulations to a set of manufacturing parameters

Biomaterials and Devices for the Circulatory System
Biomaterials and Devices for the Circulatory System

Author: Terence Gourlay

Publisher: Elsevier

Published: 2010-10-28

Total Pages: 399

ISBN-13: 0857090550

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Cardiovascular disease is one of the leading causes of death in the world today. Thanks to major advances in circulatory biomaterials and medical devices over the past few decades, many complications of this prevalent disease can be managed with great success for prolonged periods.Biomaterials and devices for the circulatory system reviews the latest developments in this important field and how they can be used to improve the success and safety in this industry.Part one discusses physiological responses to biomaterials with chapters on tissue response, blood interface and biocompatibility. Part two then reviews clinical applications including developments in valve technology, percutaneous valve replacement, bypass technologies and cardiovascular stents. Part three covers future developments in the field with topics such as nanomedicine, cardiac restoration therapy, biosensor technology in the treatment of cardiovascular disease and vascular tissue engineering.With its distinguished editors and international team of contributors Biomaterials and devices for the circulatory system is a vital reference for those concerned with bioengineering, medical devices and clinicians within this critical field. Reviews the latest developments in this important field and how they can be used to improve success and safety in the industry Both current clinical advances as well as future innovation are assessed taking a progressive view of the role of biomaterials in medical applications An examination of the physiological responses to biomaterials features tissue responses to implanted materials and strategies to improve the biocompatibility of medical devices

Biomaterials, Medical Devices and Tissue Engineering: An Integrated Approach
Biomaterials, Medical Devices and Tissue Engineering: An Integrated Approach

Author: Frederick Silver

Publisher: Springer Science & Business Media

Published: 1993-11-30

Total Pages: 318

ISBN-13: 9780412412608

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are then selected and must meet the general 'biocompatibility' require ments. Prototypes are built and tested to include biocompatibility evalua tions based on ASTM standard procedures. The device is validated for sterility and freedom from pyrogens before it can be tested on animals or humans. Medical devices are classified as class I, II or III depending on their invasiveness. Class I devices can be marketed by submitting notification to the FDA. Class II and III devices require either that they show equivalence to a device marketed prior to 1976 or that they receive pre-marketing approval. The time from device conception to FDA approval can range from months (class I device) to in excess of ten years (class III device). Therefore, much planning is necessary to pick the best regulatory approach. 2. Wound Dressings and Skin Replacement 2.1 Introduction Wounds to the skin are encountered every day. Minor skin wounds cause some pain, but these wounds will heal by themselves in time. Even though many minor wounds heal effectively without scarring in the absence of treatment, they heal more rapidly if they are kept clean and moist. Devices such as Band-Aids are used to assist in wound healing. For deeper wounds, a variety of wound dressings have been developed including cell cultured artificial skin. These materials are intended to promote healing of skin damaged or removed as a result of skin grafting, ulceration, burns, cancer excision or mechanical trauma.