Applied Statistics for Network Biology

Applied Statistics for Network Biology

Author: Matthias Dehmer

Publisher: John Wiley & Sons

Published: 2011-04-08

Total Pages: 441

ISBN-13: 3527638083

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The book introduces to the reader a number of cutting edge statistical methods which can e used for the analysis of genomic, proteomic and metabolomic data sets. In particular in the field of systems biology, researchers are trying to analyze as many data as possible in a given biological system (such as a cell or an organ). The appropriate statistical evaluation of these large scale data is critical for the correct interpretation and different experimental approaches require different approaches for the statistical analysis of these data. This book is written by biostatisticians and mathematicians but aimed as a valuable guide for the experimental researcher as well computational biologists who often lack an appropriate background in statistical analysis.


Statistical and Machine Learning Approaches for Network Analysis

Statistical and Machine Learning Approaches for Network Analysis

Author: Matthias Dehmer

Publisher: John Wiley & Sons

Published: 2012-06-26

Total Pages: 269

ISBN-13: 111834698X

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Explore the multidisciplinary nature of complex networks through machine learning techniques Statistical and Machine Learning Approaches for Network Analysis provides an accessible framework for structurally analyzing graphs by bringing together known and novel approaches on graph classes and graph measures for classification. By providing different approaches based on experimental data, the book uniquely sets itself apart from the current literature by exploring the application of machine learning techniques to various types of complex networks. Comprised of chapters written by internationally renowned researchers in the field of interdisciplinary network theory, the book presents current and classical methods to analyze networks statistically. Methods from machine learning, data mining, and information theory are strongly emphasized throughout. Real data sets are used to showcase the discussed methods and topics, which include: A survey of computational approaches to reconstruct and partition biological networks An introduction to complex networks—measures, statistical properties, and models Modeling for evolving biological networks The structure of an evolving random bipartite graph Density-based enumeration in structured data Hyponym extraction employing a weighted graph kernel Statistical and Machine Learning Approaches for Network Analysis is an excellent supplemental text for graduate-level, cross-disciplinary courses in applied discrete mathematics, bioinformatics, pattern recognition, and computer science. The book is also a valuable reference for researchers and practitioners in the fields of applied discrete mathematics, machine learning, data mining, and biostatistics.


Fundamentals Of Network Biology

Fundamentals Of Network Biology

Author: Wenjun Zhang

Publisher: World Scientific

Published: 2018-05-18

Total Pages: 568

ISBN-13: 1786345102

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As the first comprehensive title on network biology, this book covers a wide range of subjects including scientific fundamentals (graphs, networks, etc) of network biology, construction and analysis of biological networks, methods for identifying crucial nodes in biological networks, link prediction, flow analysis, network dynamics, evolution, simulation and control, ecological networks, social networks, molecular and cellular networks, network pharmacology and network toxicology, big data analytics, and more.Across 12 parts and 26 chapters, with Matlab codes provided for most models and algorithms, this self-contained title provides an in-depth and complete insight on network biology. It is a valuable read for high-level undergraduates and postgraduates in the areas of biology, ecology, environmental sciences, medical science, computational science, applied mathematics, and social science.


Computational Network Analysis with R

Computational Network Analysis with R

Author: Matthias Dehmer

Publisher: John Wiley & Sons

Published: 2016-12-12

Total Pages: 364

ISBN-13: 3527339582

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This new title in the well-established "Quantitative Network Biology" series includes innovative and existing methods for analyzing network data in such areas as network biology and chemoinformatics. With its easy-to-follow introduction to the theoretical background and application-oriented chapters, the book demonstrates that R is a powerful language for statistically analyzing networks and for solving such large-scale phenomena as network sampling and bootstrapping. Written by editors and authors with an excellent track record in the field, this is the ultimate reference for R in Network Analysis.


Analyzing Network Data in Biology and Medicine

Analyzing Network Data in Biology and Medicine

Author: Nataša Pržulj

Publisher: Cambridge University Press

Published: 2019-03-28

Total Pages: 647

ISBN-13: 1108386245

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The increased and widespread availability of large network data resources in recent years has resulted in a growing need for effective methods for their analysis. The challenge is to detect patterns that provide a better understanding of the data. However, this is not a straightforward task because of the size of the data sets and the computer power required for the analysis. The solution is to devise methods for approximately answering the questions posed, and these methods will vary depending on the data sets under scrutiny. This cutting-edge text introduces biological concepts and biotechnologies producing the data, graph and network theory, cluster analysis and machine learning, before discussing the thought processes and creativity involved in the analysis of large-scale biological and medical data sets, using a wide range of real-life examples. Bringing together leading experts, this text provides an ideal introduction to and insight into the interdisciplinary field of network data analysis in biomedicine.


Discriminative Pattern Discovery on Biological Networks

Discriminative Pattern Discovery on Biological Networks

Author: Fabio Fassetti

Publisher: Springer

Published: 2017-09-01

Total Pages: 51

ISBN-13: 3319634771

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This work provides a review of biological networks as a model for analysis, presenting and discussing a number of illuminating analyses. Biological networks are an effective model for providing insights about biological mechanisms. Networks with different characteristics are employed for representing different scenarios. This powerful model allows analysts to perform many kinds of analyses which can be mined to provide interesting information about underlying biological behaviors. The text also covers techniques for discovering exceptional patterns, such as a pattern accounting for local similarities and also collaborative effects involving interactions between multiple actors (for example genes). Among these exceptional patterns, of particular interest are discriminative patterns, namely those which are able to discriminate between two input populations (for example healthy/unhealthy samples). In addition, the work includes a discussion on the most recent proposal on discovering discriminative patterns, in which there is a labeled network for each sample, resulting in a database of networks representing a sample set. This enables the analyst to achieve a much finer analysis than with traditional techniques, which are only able to consider an aggregated network of each population.


Networks of Networks in Biology

Networks of Networks in Biology

Author: Narsis A. Kiani

Publisher: Cambridge University Press

Published: 2021-04

Total Pages: 215

ISBN-13: 1108428878

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Introduces network inspired approaches for the analysis and integration of large, heterogeneous data sets in the life sciences.


Computational Network Analysis with R

Computational Network Analysis with R

Author: Matthias Dehmer

Publisher: John Wiley & Sons

Published: 2016-07-22

Total Pages: 368

ISBN-13: 3527694404

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This new title in the well-established "Quantitative Network Biology" series includes innovative and existing methods for analyzing network data in such areas as network biology and chemoinformatics. With its easy-to-follow introduction to the theoretical background and application-oriented chapters, the book demonstrates that R is a powerful language for statistically analyzing networks and for solving such large-scale phenomena as network sampling and bootstrapping. Written by editors and authors with an excellent track record in the field, this is the ultimate reference for R in Network Analysis.


Computational Network Theory

Computational Network Theory

Author: Matthias Dehmer

Publisher: John Wiley & Sons

Published: 2015-04-28

Total Pages: 200

ISBN-13: 3527691537

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This comprehensive introduction to computational network theory as a branch of network theory builds on the understanding that such networks are a tool to derive or verify hypotheses by applying computational techniques to large scale network data. The highly experienced team of editors and high-profile authors from around the world present and explain a number of methods that are representative of computational network theory, derived from graph theory, as well as computational and statistical techniques. With its coherent structure and homogenous style, this reference is equally suitable for courses on computational networks.


Advances in Network Complexity

Advances in Network Complexity

Author: Matthias Dehmer

Publisher: John Wiley & Sons

Published: 2013-06-21

Total Pages: 298

ISBN-13: 3527670483

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A well-balanced overview of mathematical approaches to complex systems ranging from applications in chemistry and ecology to basic research questions on network complexity. Matthias Dehmer, Abbe Mowshowitz, and Frank Emmert-Streib, well-known pioneers in the fi eld, have edited this volume with a view to balancing classical and modern approaches to ensure broad coverage of contemporary research problems. The book is a valuable addition to the literature and a must-have for anyone dealing with network compleaity and complexity issues.