Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies
Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies

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Publisher: Elsevier

Published: 1999-11-01

Total Pages: 614

ISBN-13: 0080496709

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Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. For example, methods that inhibit gene expression permit studies which probe the normal function of a specific product within a cell. Such methodology can be used in many disciplines such as pharmacology, oncology, genetics, cell biology, developmental biology, molecular biology, biochemistry, and neurosciences. This volume will be a truly important tool in biomedical-oriented research.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Antisense Technology, Part B: Applications
Antisense Technology, Part B: Applications

Author:

Publisher: Elsevier

Published: 1999-11-10

Total Pages: 683

ISBN-13: 0080496717

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Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. For example, methods which inhibit gene expression permit studies probing the normal function of a specific product within a cell. Such methodology can be used in many disciplines such as pharmacology, oncology, genetics, cell biology, developmental biology, molecular biology, biochemistry, and neurosciences. This volume will be a truly important tool in biomedically-oriented research.The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today-truly an essential publication for researchers in all fields of life sciences.

Antisense Drug Technology
Antisense Drug Technology

Author: Stanley T. Crooke

Publisher: CRC Press

Published: 2007-07-25

Total Pages: 858

ISBN-13: 1439832501

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Extensively revised and updated, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition reflects the logarithmic progress made in the past four years of oligonucleotide-based therapies, and, in particular, antisense therapeutics and research. Interpreting lessons learned from the clinical trials of first generati

Therapeutic Oligonucleotides
Therapeutic Oligonucleotides

Author: Jens Kurreck

Publisher: Royal Society of Chemistry

Published: 2008

Total Pages: 362

ISBN-13: 0854041168

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This book provides a compelling overall update on current status of RNA interference

The Unfolded Protein Response and Cellular Stress, Part C
The Unfolded Protein Response and Cellular Stress, Part C

Author:

Publisher: Academic Press

Published: 2011-02-14

Total Pages: 465

ISBN-13: 0123859298

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This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights - This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation - The authors explain how these methods are able to provide important biological insights

Cryo-EM Part A: Sample Preparation and Data Collection
Cryo-EM Part A: Sample Preparation and Data Collection

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Publisher: Academic Press

Published: 2010-09-30

Total Pages: 466

ISBN-13: 0080956955

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Cryo-EM Part A: Sample Preparation and Data Collection is dedicated to a description of the instruments, samples, protocols, and analyses that belong to cryo-EM. It emphasizes the relatedness of the ideas, instrumentation, and methods underlying all cryo-EM approaches, which allow practitioners to easily move between them. Within each section, the articles are ordered according to the most common symmetry of the sample to which their methods are applied. - Includes time-tested core methods and new innovations applicable to any researcher - Methods included are useful to both established researchers and newcomers to the field - Relevant background and reference information given for procedures can be used as a guide

Hyperthermophilic Enzymes, Part C
Hyperthermophilic Enzymes, Part C

Author:

Publisher: Elsevier

Published: 2001-06-05

Total Pages: 561

ISBN-13: 0080496865

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The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today-truly an essential publication for researchers in all fields of life sciences.This volume and its companions (Volumes 330 and 331) cover all current knowledge concerning hyperthermophilic enzymes. Major topics in this volume include redox and thiol-dependent proteins, nucleic acid modifying enzymes, and protein stability from biochemical and biophysical standpoints.

Cilia, Part A
Cilia, Part A

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Publisher: Academic Press

Published: 2013-03-12

Total Pages: 469

ISBN-13: 0123984866

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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cilia and includes chapters on such topics as electron microscopy of IFT in cilia and flagella, radial spoke isolation and assays, and biomechanical measurements of kinocilium. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers cilia - Contains chapters on such topics as electron microscopy of IFT in cilia and flagella, radial spoke isolation and assays, and biomechanical measurements of kinocilium

Cilia, Part B
Cilia, Part B

Author:

Publisher: Academic Press

Published: 2013-03-16

Total Pages: 497

ISBN-13: 0123984858

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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cilia and includes chapters on such topics as methods for studying ciliary polarity in Xenopus, analysis of signaling pathways in mammalian spermatozoa, and biochemical and physiological analysis of axonemal dyneins. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers cilia - Contains chapters on such topics as methods for studying ciliary polarity in Xenopus, analysis of signaling pathways in mammalian spermatozoa, and biochemical and physiological analysis of axonemal dyneins

Redox Cell Biology and Genetics, Part B
Redox Cell Biology and Genetics, Part B

Author:

Publisher: Elsevier

Published: 2002-06-18

Total Pages: 673

ISBN-13: 0080497004

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The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. - Protein Structure and Function - Nucleic Acids and Genes