The Laboratory Rat

The Laboratory Rat

Author: George J. Krinke

Publisher: Elsevier

Published: 2000-06-20

Total Pages: 783

ISBN-13: 0080533469

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This reference series will provide all researchers using laboratory animals with comprehensive practical information on the various species. Each title in the series is devoted to a particular species, and draws together all available data in a "one-stop", easily accessible source. Each has similar format, with sections on the strains available, their husbandry, and special diets. Also included are sections on gross anatomy, endocrinology, and reproduction, followed by more detailed sections on neuroanatomy, vasculature, cell biology, and histology of particular organs and structures, and a section on molecular biology. High quality illustrations are included throughout and a color plate section is provided. A glossary, list of equipment suppliers, and "Quick Reference Section" are added features. The "Quick Reference Section" brings together all tables from the text, allowing readers to find data swiftly. The first volume in The Handbook of Experimental Animals Series, The Laboratory Rat, provides researchers in academia and industry using laboratory animals with comprehensive, practical information on the species. The Laboratory Rat has been divided into eight sections dealing with:* Strains and their selection for research* Housing and maintenance* Pathogens and diseases* Breeding and reproduction* Anatomy* Physiology* Procedures, including experimental surgery* Emerging techniques, including genetic engineering and molecular technologyKey Features* Provides a valuable, comprehensive reference source for anybody working with the laboratory rat* Formatted in a two-color, user-friendly layout* Includes high-quality illustrations throughout as well as a color plate section* Glossary* Tables in the text are also arranged into one Quick Reference Section for ease of access to the data* Appendix of equipment suppliers


The Laboratory Rat

The Laboratory Rat

Author: Mark A. Suckow

Publisher: Elsevier

Published: 2005-12-20

Total Pages: 929

ISBN-13: 0080454321

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The Laboratory Rat, Second Edition features updated information on a variety of topics including: rat genetics and genomics, both spontaneous and induced disease; state-of-the-art technology for housing and husbandry; occupational health, and experimental models. A premier source of information on the laboratory rat that will be of interest to veterinary and medical students, senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research. - At least 50% new information than first edition - Includes topics on rat genetics and genomics, occupational health, and experimental models - The premier source of information on the laboratory rat


Essentials of Laboratory Animal Science: Principles and Practices

Essentials of Laboratory Animal Science: Principles and Practices

Author: P. Nagarajan

Publisher: Springer Nature

Published: 2021-07-23

Total Pages: 797

ISBN-13: 981160987X

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This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.


The Laboratory Rat, Second Edition

The Laboratory Rat, Second Edition

Author: Patrick Sharp

Publisher: CRC Press

Published: 2012-12-11

Total Pages: 403

ISBN-13: 1439829861

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Rats have long been recognized as a valuable biomedical research model, notably in the investigation of aging, toxicology, addiction, and common human diseases such as diabetes and hypertension. In many instances, individuals conducting such research studies are charged with important responsibilities, including animal facility management, animal husbandry, veterinary care, regulatory compliance, and various experimental methodologies. With the advent of genetic manipulations and biomedical research technological advances such as bioimaging, the versatility and usefulness of the rat as an animal model has soared. The Laboratory Rat, Second Edition captures the multiple advances in this important animal model’s husbandry, veterinary care, and experimental methodology. This edition features augmented, expanded, and novel information on biology, anesthesia, analgesia, and experimental techniques benefiting personnel working with rats—from the animal care staff to the researcher and everyone in between. The book is also extremely useful to institutional animal care and use program supporters and elements, including animal care and use committees, institutional officials, occupational health and safety professionals, veterinary technicians, and veterinarians.


Rat Experimental Transplantation Surgery

Rat Experimental Transplantation Surgery

Author: Peter Girman

Publisher: Springer

Published: 2015-11-16

Total Pages: 257

ISBN-13: 3319145592

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The aim of the book is to describe tested microsurgical procedures of kidney, pancreas, islets, heat, liver and small bowel transplantation. All procedures written in the book are used in our experimental research laboratory and their description will be provided by an experienced researcher. The book is organized into ‘General’ and ‘Specific’ sections. The ‘General’ section will include principles, doses and available drugs for rat anaesthesia, the surgical anatomy of the rat, a brief review of immunosuppressant’s used in rat models, a description of basic surgical techniques and blood sampling. The ‘Specific’ section will include a description of the rat model with the appropriate organ failure relevant to the organ transplantation, which will be followed by a detailed description of the surgical procedure with high quality pictures of key steps. Each chapter will describe ‘tips and tricks’ including practical advice and recommendations.


Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals

Author: National Research Council

Publisher: National Academies Press

Published: 2011-01-27

Total Pages: 246

ISBN-13: 0309154006

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A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.


Anatomy and Dissection of the Rat

Anatomy and Dissection of the Rat

Author: Warren F. Walker

Publisher: Macmillan

Published: 1997-12-15

Total Pages: 148

ISBN-13: 9780716726357

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The careful explanation of each step of the dissection, helpful diagrams and illustrations, and detailed discussion of the structure and function of each system in Anatomy and Dissection of the Rat, Third Edition, optimize the educational value of the dissection process. These laboratory exercises are available as a bound set for the first time ever; They’re still offered separately, as well. This popular series, which includes Anatomy and Dissection of the Frog and Anatomy and Dissection of the Fetal Pig, is geared toward introductory courses in biology, comparative anatomy, and zoology.


Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research

Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research

Author: Robert L. Maynard

Publisher: Academic Press

Published: 2019-02-08

Total Pages: 379

ISBN-13: 0128118717

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Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research presents the detailed systematic anatomy of the rat, with a focus on toxicological needs. Most large works dealing with the laboratory rat provide a chapter on anatomy, but fall far short of the detailed account in this book which also focuses on the needs of toxicologists and others who use the rat as a laboratory animal. The book includes detailed guides on dissection methods and the location of specific tissues in specific organ systems. Crucially, the book includes classic illustrations from Miss H. G. Q. Rowett, along with new color photo-micrographs. Written by two of the top authors in their fields, this book can be used as a reference guide and teaching aid for students and researchers in toxicology. In addition, veterinary/medical students, researchers who utilize animals in biomedical research, and researchers in zoology, comparative anatomy, physiology and pharmacology will find this book to be a great resource. - Illustrated with over a hundred black and white and color images to assist understanding - Contains detailed descriptions and explanations to accompany all images helping with self-study - Designed for toxicologic research for people from diverse backgrounds including biochemistry, pharmacology, physiology, immunology, and general biomedical sciences