Advances in Cystic Fibrosis, An Issue of Clinics in Chest Medicine, E-Book

Advances in Cystic Fibrosis, An Issue of Clinics in Chest Medicine, E-Book

Author: Clemente J. Britto

Publisher: Elsevier Health Sciences

Published: 2022-11-09

Total Pages: 281

ISBN-13: 0323849628

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In this issue of Clinics in Chest Medicine, guest editors Drs. Clemente J. Britto and Jennifer L. Taylor-Cousar bring their considerable expertise to Advances in Cystic Fibrosis. Top experts in the field cover key topics such as genetics of cystic fibrosis (CF): clinical implications; innate and adaptive immunity in CF; novel applications of biomarkers and personalized medicine to define the spectrum of CF; emerging approaches to understand CF pathogenesis; and more. Contains 18 relevant, practice-oriented topics including novel approaches to multidrug resistant infections in CF; clinical outcomes of highly-effective modulator therapy; nontuberculous mycobacterial infections in CF; management of mental health in CF; sexual and reproductive health in CF; nutritional management in CF; transitions of care in CF; and more. Provides in-depth clinical reviews on advances in cystic fibrosis, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.


Advances in Cystic Fibrosis, an Issue of Clinics in Chest Medicine: Volume 43-4

Advances in Cystic Fibrosis, an Issue of Clinics in Chest Medicine: Volume 43-4

Author: Clemente J. Britto

Publisher: Elsevier

Published: 2022-12-28

Total Pages: 0

ISBN-13: 9780323849616

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In this issue of Clinics in Chest Medicine, guest editors Drs. Clemente J. Britto and Jennifer L. Taylor-Cousar bring their considerable expertise to Advances in Cystic Fibrosis. Top experts in the field cover key topics such as genetics of cystic fibrosis (CF): clinical implications; innate and adaptive immunity in CF; novel applications of biomarkers and personalized medicine to define the spectrum of CF; emerging approaches to understand CF pathogenesis; and more. Contains 18 relevant, practice-oriented topics including novel approaches to multidrug resistant infections in CF; clinical outcomes of highly-effective modulator therapy; nontuberculous mycobacterial infections in CF; management of mental health in CF; sexual and reproductive health in CF; nutritional management in CF; transitions of care in CF; and more. Provides in-depth clinical reviews on advances in cystic fibrosis, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.


Cystic Fibrosis, An Issue of Clinics in Chest Medicine

Cystic Fibrosis, An Issue of Clinics in Chest Medicine

Author: Jon Koff

Publisher: Elsevier Health Sciences

Published: 2016-02-10

Total Pages: 185

ISBN-13: 0323416411

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Dr. Jon Koff has assembled and expert team of authors of the topic of Cystic Fibrosis. Articles include: Epidemiology and Pathobiology, Genetics and genetic medicine in Cystic Fibrosis, Innate and Adaptive Immunity in Cystic Fibrosis, Microbiome in Cystic Fibrosis, Diagnostic Testing in Cystic Fibrosis, Treating Pseudomonas in Cystic Fibrosis, Diagnosis of Adult Patients with Cystic Fibrosis, Transition from Pediatrics to Adult Care, Lung Transplant in Cystic Fibrosis, and more!


Cystic Fibrosis, An Issue of Pediatric Clinics of North America, E-Book

Cystic Fibrosis, An Issue of Pediatric Clinics of North America, E-Book

Author: Susan G. Marshall

Publisher: Elsevier Health Sciences

Published: 2016-08-09

Total Pages: 233

ISBN-13: 0323459846

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Cystic Fibrosis (CF) is a multisystem disease whose symptoms and signs involve the gastrointestinal tract (thus affecting nutritional status), endocrine system, reproductive system and the respiratory tract (nose, sinuses and lungs). Despite new treatments, the median survival for patients with CF is less than optimal, primarily due to complications of obstructive lung disease. Currently there are approximately 60,000-80,000 people worldwide with CF. The clinical manifestations of CF are caused by dysfunction of CFTR (cystic fibrosis transmembrane conductance regulator), a multifunctional cyclic-AMP regulated ion channel protein. Over time, there has been dramatic improvement in CF patient life expectancy, in large part related to earlier diagnosis (newborn screening), better understanding of molecular genetics and underlying pathophysiology, the integrated and highly specialized Cystic Fibrosis Foundation Accredited Care Centers, and development of a wide range of new treatments and therapies, some of which target the basic CFTR defect. This edition of Pediatric Clinics of North America will offer general pediatricians and family physicians, as well as subspecialists, an update of the extraordinary progress made in the understanding and treatment of Cystic Fibrosis.


Cystic Fibrosis, Third Edition

Cystic Fibrosis, Third Edition

Author: Margaret Hodson

Publisher: CRC Press

Published: 2012-12-11

Total Pages: 523

ISBN-13: 1444113690

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This international and authoritative work, which brings together current knowledge in the field of cystic fibrosis, has become established in previous editions as a leading reference in the field. The third edition continues to provide everything that the clinician or allied health professional treating patients with cystic fibrosis will need in a single manageable volume. Thoroughly revised and updated throughout, it reflects the significant advances that have been made in the field since the second edition published in 2000. Cystic Fibrosis evaluates in detail the basic science that underlies the disease and its progression, putting it into a clinical context. Diagnostic and clinical aspects are covered in depth, as are monitoring the condition and the importance of multi-disciplinary care, reflected in the sections into which the new edition has been sub-divided to improve accessibility. Future developments, including novel therapies, are covered in a concluding section. The clinical areas have been much expanded, with the introduction of separate chapters covering sleep, lung mechanics and the work of breathing, upper airway disease, insulin deficiency and diabetes, bone disease, and sexual and reproductive issues. A new section on monitoring discusses the use of databases to improve patient care, and covers monitoring in different age groups, exercise testing and the outcomes of clinical trials in these areas. Separate chapters are devoted to paramedical issues, including nursing, physiotherapy, psychology, and palliative and spiritual care. Throughout, the emphasis is on providing an up-to-date and balanced review of both the clinical and basic sciences aspects of the subject, and to reflect the multi-disciplinary nature of the cystic fibrosis care team. Drawing on the expertise of a team of international specialists from a variety of backgrounds, the third edition of Cystic Fibrosiswill continue to find a broad readership among respiratory physicians, paediatricians, specialist nurses and other health professionals working with patients with cystic fibrosis.


Hodson and Geddes' Cystic Fibrosis

Hodson and Geddes' Cystic Fibrosis

Author: Andrew Bush

Publisher: CRC Press

Published: 2023-11-20

Total Pages: 747

ISBN-13: 1000988538

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Cystic Fibrosis has seen dramatic advances in treatment since the last edition, including targeted cystic fibrosis transmembrane conductance regulator (CFTR) protein modulators for most CFTR gene abnormalities. This new fifth edition is an update and expansion of the rapid clinical and scientific advances in improving prognosis, and the impact of COVID-19, all of which has transformed conventional models of care. It covers basic science, such as how detailed understanding of the biology of the CFTR gene and protein has led to novel and beneficial therapies, as well as all aspects of clinical management in high-, middle- and low-income settings and the voices of individuals with CF from across the world. It will be a useful reference for clinicians, including all levels of trainees, across the whole multidisciplinary team, scientists and students. Key Features • Follows an appealing organization of chapters, by developing fundamental knowledge of the reader before moving on to more complex or developing topics. • Presents a comprehensive, authoritative and up-to-date text, integrating fundamental science and clinical aspects of cystic fibrosis providing an attractive read for clinicians, trainee doctors and scientists. • Draws on global expertise and reflects best evidence-based practice from experts conducting cutting-edge clinical and basic science research from around the world.


Cystic Fibrosis

Cystic Fibrosis

Author: Julian L. Allen

Publisher: CRC Press

Published: 2010-03-25

Total Pages: 0

ISBN-13: 9781439801819

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The median age of survival for those with cystic fibrosis has risen considerably in recent years. This text thoroughly examines the developments and breakthroughs which have led to this improvement in life expectancy. With a focus on the latest discoveries in the diagnosis and treatment of the disease, this book provides a comprehensive overview of the past, current and forthcoming advancements in cystic fibrosis research and clinical care.


Pediatric Respiratory Disease, an Issue of Clinics in Chest Medicine, E-Book

Pediatric Respiratory Disease, an Issue of Clinics in Chest Medicine, E-Book

Author: Erick Forno, MD MPH

Publisher: Elsevier Health Sciences

Published: 2024-08-02

Total Pages: 273

ISBN-13: 0443130043

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In this issue of Clinics in Chest Medicine, guest editors Drs. Erick Forno and Gregory Sawicki bring their considerable expertise to the topic of Pediatric Respiratory Disease. Top experts discuss COVID-19 in pediatric populations; environmental exposures and pediatric respiratory disease; genetics and genomics in childhood respiratory diseases; microbiome and metabolome: their role in pediatric respiratory disease; and more. Contains 21 relevant, practice-oriented topics including sickle cell disease and the lung; pediatric lung transplantation; health equity and advocacy in pediatric pulmonology; pediatric pulmonology in low-middle income countries; childhood interstitial lung diseases; primary cilliary dyskinesia; and more. Provides in-depth clinical reviews on pediatric respiratory disease, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.


Bronchiectasis, An Issue of Clinics in Chest Medicine

Bronchiectasis, An Issue of Clinics in Chest Medicine

Author: Mark L. Metersky

Publisher: Elsevier Health Sciences

Published: 2012-06-11

Total Pages: 220

ISBN-13: 1455738433

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The first issue of Clinics in Chest Medicine to be published with this focus, this issue reviews bronchiectasis from numerous angles to provide comprehensive coverage on this important subject. Epidemiology, airway defense mechanisms, pathogenesis, imaging and genetic causes of bronchiectasis are discussed. Allergic bronchopulmonary aspergillosis is addressed, as well as non-tuberculous mycobacteria as a cause of bronchiectasis. Authors examine how to evaluate the success of therapy for bronchiectasis (what endpoints to use) and then discuss a variety of therapy options: inhaled and systemic antibiotic treatment, chest physiotherapy, pharmacologic agents for mucous clearance, antipinflammatory therapy and macrolides. Pulmonary resection and lung transplantation for bronchiectasis are reviewed. Recent advances in Cystic Fibrosis are also discussed.