Evolution of Translational Omics
Evolution of Translational Omics

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2012-09-13

Total Pages: 354

ISBN-13: 0309224187

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Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Current Catalog
Current Catalog

Author: National Library of Medicine (U.S.)

Publisher:

Published: 1983

Total Pages: 1442

ISBN-13:

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First multi-year cumulation covers six years: 1965-70.

Advancements in Clinical Medicine
Advancements in Clinical Medicine

Author: Paramasivan, P.

Publisher: IGI Global

Published: 2024-05-01

Total Pages: 453

ISBN-13:

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Healthcare professionals face a range of challenges in modern clinical medicine, from managing neurodegenerative disorders like Alzheimer's disease to treating allergic rhinitis in elderly populations. These challenges require innovative solutions, as traditional diagnostic and treatment methods may only sometimes be effective. How can clinicians navigate these challenges and provide the best possible care for their patients? Advancements in Clinical Medicine is a resource that provides practical solutions to these challenges through innovative approaches like machine learning integration and super-resolution reconstruction techniques revolutionize how we approach diagnosis and treatment. By leveraging cutting-edge technologies like artificial intelligence, this book equips scholars and practitioners with the tools they need to tackle even the most daunting medical challenges head-on.

Advances in Therapeutic Engineering
Advances in Therapeutic Engineering

Author: Wenwei Yu

Publisher: CRC Press

Published: 2012-12-03

Total Pages: 485

ISBN-13: 1439871744

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Therapeutic Engineering (TE) is a cutting-edge domain in today's era of medical technology research. Through engineering algorithms that provide technological solutions, it aims to elevate the quality of life of disabled individuals. Advances in Therapeutic Engineering describes various therapeutic processes and mechanisms currently applied to the

Clinical Genomics
Clinical Genomics

Author: Shashikant Kulkarni

Publisher: Academic Press

Published: 2014-11-10

Total Pages: 489

ISBN-13: 0124051731

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Clinical Genomics provides an overview of the various next-generation sequencing (NGS) technologies that are currently used in clinical diagnostic laboratories. It presents key bioinformatic challenges and the solutions that must be addressed by clinical genomicists and genomic pathologists, such as specific pipelines for identification of the full range of variants that are clinically important. This book is also focused on the challenges of diagnostic interpretation of NGS results in a clinical setting. Its final sections are devoted to the emerging regulatory issues that will govern clinical use of NGS, and reimbursement paradigms that will affect the way in which laboratory professionals get paid for the testing. - Simplifies complexities of NGS technologies for rapid education of clinical genomicists and genomic pathologists towards genomic medicine paradigm - Tried and tested practice-based analysis for precision diagnosis and treatment plans - Specific pipelines and meta-analysis for full range of clinically important variants

Advances in Gingival Diseases and Conditions
Advances in Gingival Diseases and Conditions

Author:

Publisher: BoD – Books on Demand

Published: 2024-10-30

Total Pages: 216

ISBN-13: 0850142733

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Advances in Gingival Diseases and Conditions offers a comprehensive overview of the latest research and clinical innovations in periodontology. Divided into two sections, the book explores the etiology, clinical aspects, and diagnosis of gingival diseases, including biomarkers, metalloproteinases, and the impact of stress. The second section presents cutting-edge treatments, from curcumin therapy and muco-gingival surgery to guided tissue engineering and peri-implant disease management. This essential resource equips dental professionals, researchers, and students with the tools and knowledge to tackle complex gingival conditions with precision and confidence.