Biomedical Applications of Microfluidic Devices

Biomedical Applications of Microfluidic Devices

Author: Michael R. Hamblin

Publisher: Academic Press

Published: 2020-11-12

Total Pages: 352

ISBN-13: 0128187921

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Biomedical Applications of Microfluidic Devices introduces the subject of microfluidics and covers the basic principles of design and synthesis of actual microchannels. The book then explores how the devices are coupled to signal read-outs and calibrated, including applications of microfluidics in areas such as tissue engineering, organ-on-a-chip devices, pathogen identification, and drug/gene delivery. This book covers high-impact fields (microarrays, organ-on-a-chip, pathogen detection, cancer research, drug delivery systems, gene delivery, and tissue engineering) and shows how microfluidics is playing a key role in these areas, which are big drivers in biomedical engineering research. This book addresses the fundamental concepts and fabrication methods of microfluidic systems for those who want to start working in the area or who want to learn about the latest advances being made. The subjects covered are also an asset to companies working in this field that need to understand the current state-of-the-art. The book is ideal for courses on microfluidics, biosensors, drug targeting, and BioMEMs, and as a reference for PhD students. The book covers the emerging and most promising areas of biomedical applications of microfluidic devices in a single place and offers a vision of the future. - Covers basic principles and design of microfluidics devices - Explores biomedical applications to areas such as tissue engineering, organ-on-a-chip, pathogen identification, and drug and gene delivery - Includes chemical applications in organic and inorganic chemistry - Serves as an ideal text for courses on microfluidics, biosensors, drug targeting, and BioMEMs, as well as a reference for PhD students


Applications of Microfluidic Systems in Biology and Medicine

Applications of Microfluidic Systems in Biology and Medicine

Author: Manabu Tokeshi

Publisher: Springer

Published: 2024-10-30

Total Pages: 0

ISBN-13: 9789819765393

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This book is the second edition of the one originally published in 2016, which focused on state-of-the-art microfluidic research in medical and biological applications. Similar to the first edition, beginners in the field —undergraduates, engineers, biologists, medical and pharmaceutical researchers—will easily learn to understand microfluidic-based medical and biological applications. Because a wide range of topics is summarized here, it also helps experts to learn more about fields outside their own specialties. In this second edition, significant revisions have been made to chapters covering technologies that have seen major advancements, such as acoustofluidics, protein crystallography, organ-on-a-chip systems, nanopore sensing, and paper-based microfluidics. In addition, the chapters on cancer diagnosis using exosomes and single-cell sequencing using droplet microfluidics, which are attracting attention as new technologies, have been newly added. Readers will be convinced that microfluidic devices have great potential for medical and biological applications.


Microfluidics for Pharmaceutical Applications

Microfluidics for Pharmaceutical Applications

Author: Hélder A. Santos

Publisher: William Andrew

Published: 2018-10-18

Total Pages: 0

ISBN-13: 9780128126592

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Microfluidics for Pharmaceutical Applications: From Nano/Micro Systems Fabrication to Controlled Drug Delivery is a concept-orientated reference that features case studies on utilizing microfluidics for drug delivery applications. It is a valuable learning reference on microfluidics for drug delivery applications and assists practitioners developing novel drug delivery platforms using microfluidics. It explores advances in microfluidics for drug delivery applications from different perspectives, covering device fabrication, fluid dynamics, cutting-edge microfluidic technology in the global drug delivery industry, lab-on-chip nano/micro fabrication and drug encapsulation, cell encapsulation and delivery, and cell- drug interaction screening. These microfluidic platforms have revolutionized the drug delivery field, but also show great potential for industrial applications.


Microfluidics

Microfluidics

Author: Yu Song

Publisher: John Wiley & Sons

Published: 2018-05-07

Total Pages: 576

ISBN-13: 3527341064

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The first book offering a global overview of fundamental microfluidics and the wide range of possible applications, for example, in chemistry, biology, and biomedical science. As such, it summarizes recent progress in microfluidics, including its origin and development, the theoretical fundamentals, and fabrication techniques for microfluidic devices. The book also comprehensively covers the fluid mechanics, physics and chemistry as well as applications in such different fields as detection and synthesis of inorganic and organic materials. A useful reference for non-specialists and a basic guideline for research scientists and technicians already active in this field or intending to work in microfluidics.


Microfluidic Technologies for Miniaturized Analysis Systems

Microfluidic Technologies for Miniaturized Analysis Systems

Author: Steffen Hardt

Publisher: Springer Science & Business Media

Published: 2007-09-29

Total Pages: 630

ISBN-13: 0387684247

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This book addresses Lab-on-a-Chip devices. It focuses on microfluidic technologies that have emerged in the past decade. Coverage presents a comprehensive listing of the most promising microfluidic technologies in the Lab-on-a-Chip field. It also details technologies that can be viewed as toolboxes needed to set up complex Lab-on-a-Chip systems.


Micro Total Analysis Systems

Micro Total Analysis Systems

Author: Albert Berg

Publisher: Springer Science & Business Media

Published: 1995

Total Pages: 330

ISBN-13: 9780792332176

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The use of silicon-based microsystems for chemical analysis is one of the most promising concepts in the recent developments in micro system technology (MST). It is expected that chemical sensors will be increasingly integrated in so-called miniaturized total analysis systems (muTAS), a concept first presented by Ciba-Geigy. In such systems, all steps in a chemical determination, from sampling to detection and data treatment, are integrated in one miniature instrument. muTAS offer a variety of advantages over conventional analysis systems such as improved analytical performance, reduced reagent and power consumption, small size, possibility of new and more complicated functions, higher reliability and lower fabrication costs. Application of muTAS may be found in fields like process industry, environmental monitoring, medical diagnostics, aeronautics, automotive industry, etc.


Microfluidics and Nanofluidics

Microfluidics and Nanofluidics

Author: Mohsen Sheikholeslami Kandelousi

Publisher: BoD – Books on Demand

Published: 2018-08-22

Total Pages: 320

ISBN-13: 1789235405

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In the present book, various applications of microfluidics and nanofluidics are introduced. Microfluidics and nanofluidics span a broad array of disciplines including mechanical, materials, and electrical engineering, surface science, chemistry, physics and biology. Also, this book deals with transport and interactions of colloidal particles and biomolecules in microchannels, which have great importance to many microfluidic applications, such as drug delivery in life science, microchannel heat exchangers in electronic cooling, and food processing industry. Furthermore, this book focuses on a detailed description of the thermal transport behavior, challenges and implications that involve the development and use of HTFs under the influence of atomistic-scale structures and industrial applications.


Microfluidics for Single-Cell Analysis

Microfluidics for Single-Cell Analysis

Author: Jin-Ming Lin

Publisher: Springer Nature

Published: 2019-08-28

Total Pages: 263

ISBN-13: 9813297298

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This book summarizes the various microfluidic-based approaches for single-cell capture, isolation, manipulation, culture and observation, lysis, and analysis. Single-cell analysis reveals the heterogeneities in morphology, functions, composition, and genetic performance of seemingly identical cells, and advances in single-cell analysis can overcome the difficulties arising due to cell heterogeneity in the diagnostics for a targeted model of disease. This book provides a detailed review of the state-of-the-art techniques presenting the pros and cons of each of these methods. It also offers lessons learned and tips from front-line investigators to help researchers overcome bottlenecks in their own studies. Highlighting a number of techniques, such as microfluidic droplet techniques, combined microfluidics-mass-spectrometry systems, and nanochannel sampling, it describes in detail a new microfluidic chip-based live single-cell extractor (LSCE) developed in the editor’s laboratory, which opens up new avenues to use open microfluidics in single-cell extraction, single-cell mass spectrometric analysis, single-cell adhesion analysis and subcellular operations. Serving as both an elementary introduction and advanced guidebook, this book interests and inspires scholars and students who are currently studying or wish to study microfluidics-based cell analysis methods.


Microfluidics and Lab-on-a-Chip

Microfluidics and Lab-on-a-Chip

Author: Andreas Manz

Publisher: Royal Society of Chemistry

Published: 2020-09-24

Total Pages: 307

ISBN-13: 1782628339

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Responding to the need for an affordable, easy-to-read textbook that introduces microfluidics to undergraduate and postgraduate students, this concise book will provide a broad overview of the important theoretical and practical aspects of microfluidics and lab-on-a-chip, as well as its applications.