Advancement of Phenolic Acids in Drug Discovery
Advancement of Phenolic Acids in Drug Discovery

Author: Naresh Kumar

Publisher: Elsevier

Published: 2024-06-19

Total Pages: 540

ISBN-13: 0443185395

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Advancement of Phenolic Acids in Drug Discovery: Fundamental and Applications offers comprehensive coverage of the ADMET profiles of phenolic acids, their extraction method and prospects for drug design and development. Chapters overview phenolic acids and their characterization, discuss the role of phenolic acids in plant systems, present sources and detailed extraction methods of phenolic acids, and cover phenolic acid mechanisms of action as it relates to several key diseases and health conditions, including their role as antioxidant agents, anti-inflammatory and analgesic drugs, anti-microbial drugs, anti-viral drugs, anti-cancer drugs, diabetes and metabolic dysfunctions, neurological disorders, cardiovascular diseases. The book's final chapters cover nanoscience aspects of phenolic acids, biomedical applications, and concludes with challenges and opportunities presented by phenolic acids. This is the ideal reference for researchers in the fields of drug development, both in academia and corporate settings. Researchers of related areas like food science and medicinal chemistry will also benefit from this in-depth profiling of therapeutical properties of phenolic acids. - Highlights fundamental concepts with advanced exploration of phenolic acids - Provides in-depth coverage on the design and development of novel drugs from natural phenolic acids - Reviews the changing role of phenolic acids

Phenolics in Food and Nutraceuticals
Phenolics in Food and Nutraceuticals

Author: Fereidoon Shahidi

Publisher: CRC Press

Published: 2003-07-29

Total Pages: 576

ISBN-13: 0203508734

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Phenolics in Food and Nutraceuticals is the first single-source compendium of essential information concerning food phenolics. This unique book reports the classification and nomenclature of phenolics, their occurrence in food and nutraceuticals, chemistry and applications, and nutritional and health effects. In addition, it describes antioxidant a

Water Extraction of Bioactive Compounds
Water Extraction of Bioactive Compounds

Author: Herminia Dominguez

Publisher: Elsevier

Published: 2017-09-20

Total Pages: 486

ISBN-13: 0128096152

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Water Extraction of Bioactive Compounds: From Plants to Drug Development draws together the expert knowledge of researchers from around the world to outline the essential knowledge and techniques required to successfully extract bioactive compounds for further study. The book is a practical tool for medicinal chemists, biochemists, pharmaceutical scientists and academics working in the discovery and development of drugs from natural sources. The discovery and extraction of bioactive plant compounds from natural sources is of growing interest to drug developers, adding greater fuel to a simultaneous search for efficient, green technologies to support this. Particularly promising are aqueous based methods, as water is a cheap, safe and abundant solvent. Water Extraction of Bioactive Compounds: From Plants to Drug Development is a detailed guide to the fundamental concepts and considerations needed to successfully undertake such processes, supported by application examples and highlighting the most influential variables. Beginning with an introduction to plants as sources of drugs, the book highlights the need for a move towards both more rational and greener techniques in the field, and presents multiple innovative water-based strategies for the discovery and extraction of bioactive constituents of botanicals. A broad range of available techniques are reviewed, including conventional and pressurized hot water extraction techniques, intensified processes such as microwave-assisted, ultrasound-assisted processes, and enzyme assisted extraction, and processes using combined techniques. - Covers the theoretical background and range of techniques available to researchers, helping them to select the most appropriate extraction method for their needs - Presents up-to-date and cutting edge applications by international experts - Highlights current use and future potential for industrial scale applications - Offers a thorough introduction to plants as sources of drugs, highlighting strategies for the discovery of novel bioactive constituents of botanicals

Phenolic Compounds in Foods and Natural Health Products
Phenolic Compounds in Foods and Natural Health Products

Author: Fereidoon Shahidi

Publisher:

Published: 2005

Total Pages: 328

ISBN-13:

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The book reviewed and gave new research discovery of the chemistry, analysis and health effects such as antioxidative, cancer preventive and anti-inflammatory properties of phenolic compounds in foods and natural health products.

Bio-Farms for Nutraceuticals
Bio-Farms for Nutraceuticals

Author: Maria Teresa Giardi

Publisher: Springer Science & Business Media

Published: 2011-06-26

Total Pages: 360

ISBN-13: 1441973478

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"Bio-Farms for Nutraceuticals" can be said to have been born of the NUTRA-SNACKS project within the Sixth Framework Programme Priority on Food Quality and Safety. One objective of NUTRA -SNACK S was to improve the nutritional and eating properties of ready-to-eat products and semi-prepared foodstuffs through better monitoring of the quality and safety of raw materials and the development of innovative processes along the production chain. Another main objective of the project was the production of ready-to-eat snacks with high nutraceutic activity. Seven research institutes and three companies in six European countries were involved in this effort. The co-operation resulted in the production of food having a high content of natural metabolites with the following beneficial health effects: anticancer, antilipidemic, anticholesterol, antimicrobial, antibacterial, antifungal, antiviral, antihypertensive, anti-inflamatory and antioxidant activities.

Advances in Drug Research
Advances in Drug Research

Author:

Publisher: Elsevier

Published: 1996-07-02

Total Pages: 385

ISBN-13: 0080526713

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This volume continues the trend for Advances in Drug Research of shorter, but more frequent volumes. In line with the tradition of the series, chapters on general themes are interspersed with chapters on specific drug classes and targets.

Bioactive Phytochemicals: Drug Discovery to Product Development
Bioactive Phytochemicals: Drug Discovery to Product Development

Author: Javed Ahmad

Publisher: Bentham Science Publishers

Published: 2020-10-28

Total Pages: 238

ISBN-13: 9811464464

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Natural bioactive compounds from medicinal plants are inexplicably diverse in chemical structure and biological properties. The unmet therapeutic requirements for various diseases serve as a guide for researchers to study natural compounds. These studies are intended to isolate, identify the structural characterization and eventually discover the pharmacological activity of natural compounds from their plant sources with the goal of treating specific diseases. Bioactive Phytochemicals: Drug Discovery to Product Development explores the scope and approaches of drug discovery from natural products. Chapters in the book cover information about the cultivation, collection and processing of medicinal plants, the methods and high throughput techniques for isolation and characterization of bioactive phytochemicals and pharmacological screening for activity, formulation and quality control. Information about the regulations specified for natural medicinal products in different region of the world is also presented, followed by a concluding chapter devoted to the role of natural herbal products for treatment of human diseases such as cancer, cardiovascular diseases, diabetes, obesity, inflammation and neurological disorders. Each chapter concludes with a general reference section, which is a bibliographic guide to more advanced texts. The contributing authors for this volume are drawn from a rich blend of experts in various areas of herbal medicine which encompass herbal drug discovery to product development. The concise and organized layout along with a broad coverage of phytochemistry and drug discovery makes this book a suitable reference for students of medicinal chemistry, researchers and industry professionals interested in herbal product development.

Biotechnology and Drug Development for Targeting Human Diseases
Biotechnology and Drug Development for Targeting Human Diseases

Author: Israel Valencia Quiroz

Publisher: Bentham Science Publishers

Published: 2024-03-14

Total Pages: 235

ISBN-13: 9815223178

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Biotechnology and Drug Development for Targeting Human Diseases is an insightful compendium on drug development technologies for professionals and students in biotechnology and pharmacology. This book meticulously explores the intersection of biotechnology with drug development, emphasizing its crucial role in creating new therapies for human disease. Central to the book is the innovative use of biotechnology in understanding and treating diseases. It begins with an exploration of multi-omics profiles, shedding light on disease mechanisms and drug development. Subsequent chapters explain in silico methods for drug design, the role of natural products in antimicrobial applications and wound healing, and the use of viruses as carriers in biotechnology. Key features of this reference include a blend of theoretical knowledge and practical insights, detailed analyses of molecular docking in drug discovery, the repurposing of drugs for various diseases, and the emerging field of omics technologies in drug interaction studies. Each chapter is comprehensive, offering current information backed by extensive references, making the book both a foundational and advanced resource. Readership Students and professionals in the fields of biotechnology and pharmacology.

Microbes In Applied Research: Current Advances And Challenges
Microbes In Applied Research: Current Advances And Challenges

Author: Antonio Mendez-vilas

Publisher: World Scientific

Published: 2012-06-21

Total Pages: 694

ISBN-13: 9814405051

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This book offers the latest scientific research on applied microbiology presented at the IV International Conference on Environmental, Industrial and Applied Microbiology (BioMicroWorld2011) held in Spain in 2011. A wide-ranging set of topics including agriculture, environmental, food, industrial and medical microbiology makes this book interesting not only for microbiologists, but also for anyone who likes to keep up with cutting-edge research in microbiology and microbial biotechnology.Readers will find a major collection of knowledge, approaches, methods and discussions on the latest advances and challenges in applied microbiology in a compilation of 136 chapters written by active researchers in the field from around the world.The topics covered in this single volume include biodegradation of pollutants, water, soil and plant microorganisms, biosurfactants, antimicrobial natural products, antimicrobial susceptibility, antimicrobial resistance, human pathogens, food microorganisms, fermentation, biotechnologically relevant enzymes and proteins, microbial physiology, metabolism and gene expression mainly, although many other subjects are also discussed.