Actin Cytoskeleton in Cancer Progression and Metastasis – Part C
Actin Cytoskeleton in Cancer Progression and Metastasis – Part C

Author:

Publisher: Academic Press

Published: 2021-05-04

Total Pages: 194

ISBN-13: 012824139X

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Actin Cytoskeleton in Cancer Progression and Metastasis - Part C, Volume 358 in the International Review of Cell and Molecular Biology series, provides an overview of the roles of the actin cytoskeleton and some of its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response. New chapters cover Actin isoforms in cancer, Actin cytoskeleton regulators at invadopodia, Cytoskeletal Mechanics Drives Heterogeneity in Epithelial Ovarian Cancer, and more. - Provides comprehensive and timely reviews on actin cytoskeleton and its regulators in cancer biology - Offers a wide range of perspectives for basic and translational research - Discusses opportunities and challenges for translating knowledge of tumor cell actin cytoskeleton into clinical applications

Actin Cytoskeleton in Cancer Progression and Metastasis - Part B
Actin Cytoskeleton in Cancer Progression and Metastasis - Part B

Author:

Publisher: Academic Press

Published: 2020-10-14

Total Pages: 332

ISBN-13: 0128212845

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Actin Cytoskeleton in Cancer Progression and Metastasis (Part B), Volume 356 in the International Review of Cell and Molecular Biology series, provides an overview on the roles of the actin cytoskeleton and its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, and in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response. Specific chapters in this release cover Actin dynamics during tumor cell dissemination, Actin cytoskeleton remodeling during cancer cell migration, Cytoskeletal Mechanics Drives Heterogeneity in Epithelial Ovarian Cancer, and much more. - Provides comprehensive and timely reviews on actin cytoskeleton and its regulators in cancer biology - Offers a wide range of perspectives for basic and translational research - Discusses opportunities and challenges for translating knowledge of tumor cell actin cytoskeleton into clinical applications

Actin Cytoskeleton in Cancer Progression and Metastasis - Part A
Actin Cytoskeleton in Cancer Progression and Metastasis - Part A

Author:

Publisher: Academic Press

Published: 2020-08-26

Total Pages: 256

ISBN-13: 0128212829

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Actin Cytoskeleton in Cancer Progression and Metastasis - Part A, Volume 355 in the International Review of Cell and Molecular Biology series, provides an overview of the roles of the actin cytoskeleton and some of its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response. - Provides comprehensive and timely reviews on actin cytoskeleton and its regulators in cancer biology - Offers a wide range of perspectives for basic and translational research - Discusses opportunities and challenges for translating knowledge of tumor cell actin cytoskeleton into clinical applications

The Cytoskeleton in Health and Disease
The Cytoskeleton in Health and Disease

Author: Heide Schatten

Publisher: Springer

Published: 2015-08-21

Total Pages: 395

ISBN-13: 1493929046

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This volume addresses the structural and functional roles of the cytoskeleton and its dysfunctions which often lead to disease. It provides thorough discussion of microtubules, microfilaments, intermediate filaments, and cytoskeletal functions and dysfunctions in different organ systems. Comprehensive yet concise. The Cytoskeleton In Health And Disease presents cutting-edge discoveries balanced with background information and highlights the new aspects of the research and its impact on the design of new strategies or the identification of new targets for therapeutic intervention. There is a significant need for a book on this topic, as interest in the cytoskeleton continues to grow as causes and cures for cytoskeletal diseases are further explored in biomedical research. This book is essential reading for scientists, students, and teachers interested in expanding their knowledge related to the cytoskeleton. New researchers entering the field will find classic and well as contemporary information not easily found in the current literature or internet resources.

Actin Cytoskeleton in Cancer Progression and Metastasis - Part C
Actin Cytoskeleton in Cancer Progression and Metastasis - Part C

Author:

Publisher: Academic Press

Published: 2021-05-06

Total Pages: 0

ISBN-13: 9780128241387

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Actin Cytoskeleton in Cancer Progression and Metastasis - Part C, Volume 358 in the International Review of Cell and Molecular Biology series, provides an overview of the roles of the actin cytoskeleton and some of its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response. New chapters cover Actin isoforms in cancer, Actin cytoskeleton regulators at invadopodia, Cytoskeletal Mechanics Drives Heterogeneity in Epithelial Ovarian Cancer, and more.

International Review of Cell and Molecular Biology
International Review of Cell and Molecular Biology

Author: Kwang W. Jeon

Publisher: Academic Press

Published: 2014-11-18

Total Pages: 277

ISBN-13: 0128003111

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International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a world-wide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists. - Authored by some of the foremost scientists in the field - Provides comprehensive reviews and current advances - Wide range of perspectives on specific subjects - Valuable reference material for advanced undergraduates, graduate students and professional scientists

Cytoskeleton
Cytoskeleton

Author: Jose C. Jimenez-Lopez

Publisher: BoD – Books on Demand

Published: 2017-05-17

Total Pages: 344

ISBN-13: 9535131699

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The cytoskeleton is a highly dynamic intracellular platform constituted by a three-dimensional network of proteins responsible for key cellular roles as structure and shape, cell growth and development, and offering to the cell with "motility" that being the ability of the entire cell to move and for material to be moved within the cell in a regulated fashion (vesicle trafficking). The present edition of Cytoskeleton provides new insights into the structure-functional features, dynamics, and cytoskeleton's relationship to diseases. The authors' contribution in this book will be of substantial importance to a wide audience such as clinicians, researches, educators, and students interested in getting updated knowledge about molecular basis of cytoskeleton, such as regulation of cell vital processes by actin-binding proteins as cell morphogenesis, motility, their implications in cell signaling, as well as strategies for clinical trial and alternative therapies based in multitargeting molecules to tackle diseases, that is, cancer.

Systems Biology of Cancer
Systems Biology of Cancer

Author: Sam Thiagalingam

Publisher: Cambridge University Press

Published: 2015-04-09

Total Pages: 597

ISBN-13: 0521493390

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An overview of the current systems biology-based knowledge and the experimental approaches for deciphering the biological basis of cancer.

Extracellular Matrix Degradation
Extracellular Matrix Degradation

Author: William C. Parks

Publisher: Springer Science & Business Media

Published: 2011-04-07

Total Pages: 262

ISBN-13: 3642168612

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Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have been the focus of research that touches on development, tissue remodeling, inflammation and disease. This volume in the Biology of Extracellular Matrix series provides a review of the known classes of proteases that degrade ECM both outside and inside the cell. The specific EMC proteases that are discussed include cathepsins, bacterial collagenases, matrix metalloproteinases, meprins, serine proteases, and elastases. The volume also discusses the domains responsible for specific biochemical characteristics of the proteases and the physical interactions that occur when the protease interacts with substrate. The topics covered in this volume provide an important context for understanding the role that matrix-degrading proteases play in normal tissue remodeling and in diseases such as cancer and lung disease.