Immunity

Immunity

Author: Luba Vikhanski

Publisher: Chicago Review Press

Published: 2016-04-01

Total Pages: 258

ISBN-13: 1613731132

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Around Christmas of 1882, while peering through a microscope at starfish larvae in which he had inserted tiny thorns, Russian zoologist Elie Metchnikoff had a brilliant insight: what if the mobile cells he saw gathering around the thorns were nothing but a healing force in action? Metchnikoff's daring theory of immunity—that voracious cells he called phagocytes formed the first line of defense against invading bacteria—would eventually earn the scientist a Nobel Prize, shared with his archrival, as well as the unofficial moniker "Father of Natural Immunity." But first he had to win over skeptics, especially those who called his theory "an oriental fairy tale." Using previously inaccessible archival materials, author Luba Vikhanski chronicles Metchnikoff's remarkable life and discoveries in the first moder n biography of this hero of medicine. Metchnikoff was a towering figure in the scientific community of the early twentieth century, a tireless humanitarian who, while working at the Pasteur Institute in Paris, also strived to curb the spread of cholera, syphilis, and other deadly diseases. In his later years, he startled the world with controversial theories on longevity, launching a global craze for yogurt, and pioneered research into gut microbes and aging. Though Metchnikoff was largely forgotten for nearly a hundred years, Vikhanski documents a remarkable revival of interest in his ideas on immunity and on the gut flora in the science of the twenty-first century.


Library Notes

Library Notes

Author: University of North Carolina (1793-1962). Woman's College. Library

Publisher:

Published: 1923

Total Pages: 32

ISBN-13:

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Biochemistry And Physiology of Nutrition

Biochemistry And Physiology of Nutrition

Author: Geoffrey Bourne

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 654

ISBN-13: 0323143881

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Biochemistry and Physiology of Nutrition, Volume II focuses on the processes, methods, and studies on nutrition. The book starts by discussing intracellular localization through histochemical methods of enzymes and vitamins; the structural changes in vitamin deficiency; and microbiology of digestion. Deficiencies in vitamins, A, C, D, E, B1, riboflavin, nicotinic acid, choline, biotin, and folic acid are noted. The book then focuses on microbiology of digestion, considering the establishment of microbial population in the alimentary tract, results of microbial digestion, antibiotics, and intestinal flora of man. The text also defines the nutrition system of worms, insects, and protozoa. The generation of ATP in terminal respiration and anaerobic glycolysis, as well as ATP's role in energy transfer, is noted. The discussions also focus on hydrolytic and phosphorylitic enzymes, such as carbohydrates, esterases, amidases, phosphatases, and phosporylases. Other topics covered are respiratory enzymes and coenzymes in which nucleotides, glucose diphosphate, diphosphoglyceric acid, and thiamine pyrophosphate are noted. The book notes the functions of iron compounds in the body, particularly in blood and tissues, and then touches on calcium and phosphorus metabolism. Given considerations are calcium and phosphorus in blood, skeletal calcium and phosphorus, and the factors affecting adsorption. A discussion also focuses on trace elements and the effects of protein, carbohydrates, fats, and vitamins in nutrition. The book is a vital source of data for readers interested in studying the elements, factors, processes, and methods involved in nutrition.