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Prostate Cancer

Author: Scott M. Dehm

Publisher: Springer Nature

Published: 2020-01-03

Total Pages: 483

ISBN-13: 303032656X

The purpose of this book is to provide a contemporary overview of the causes and consequences of prostate cancer from a cellular and genetic perspective. Written by experts in the fields of epidemiology, toxicology, cell biology, genetics, genomics, cell-cell interactions, cell signaling, hormone signaling, and transcriptional regulation, the text covers aspects of prostate cancer from disease initiation to metastasis. Chapters explore in depth the cells of origin for prostate cancer, its genomic subtypes, neural transcription factors in disease progression, epigenetic regulation of chromatin, and many other topics. This book distinguishes itself from other texts on prostate cancer by its focus on cellular and genetic mechanisms, as opposed to clinical diagnosis and management. As a result, this book will be of broad interest to basic and translational scientists with familiarity of these topics, as well as to trainees at earlier stages of their research careers.

A History of Prostate Cancer

Author: Helen Valier

Publisher: Palgrave Macmillan

Published: 2017-08-31

Total Pages: 241

ISBN-13: 9781349739387

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This book offers a comprehensive and inclusive insight into the history of prostate cancer and its sufferers. Until recently, little practical help could be offered for men afflicted with the devastating diseases of the genitourinary organs. This is despite complaints of painful urination from aging men being found in ancient medical manuscripts, despite the anatomical discoveries of the European Renaissance and despite the experimental surgical researches of the eighteen and nineteenth centuries. As diseases of the prostate, including prostate cancer, came to be better understood in the early twentieth century, therapeutic nihilism continued as curative radical surgeries and radiotherapy failed. The therapeutic ‘turn’ came with hormonal therapies, itself a product of the explosive growth of U.S. biomedicine from the 1940s onwards. By the 1990s, prostate cancer screening had become a somewhat ubiquitous but controversial feature of the medical encounter for American men as they aged, which greatly influenced the treatment pathways and identity of the male patient: as victim, as hero, and ultimately, as consumer.

Dr. Patrick Walsh's Guide to Surviving Prostate Cancer

Author: Patrick C. Walsh

Publisher: Balance

Published: 2018-05-15

Total Pages: 480

ISBN-13: 153876363X

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This guide covers every aspect of prostate cancer, from potential causes including diet to tests for diagnosis, curative treatment, and innovative means of controlling advanced stages of cancer.

Prostate Cancer Prevention

Author: Jack Cuzick

Publisher: Springer Science & Business Media

Published: 2014-02-15

Total Pages: 167

ISBN-13: 3642451950

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Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5α-reductase inhibitors, DFMO and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers.

Adenocarcinoma of the Prostate

Author: Andrew W. Bruce

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 363

ISBN-13: 1447113985

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Carcinoma of the prostate increasingly dominates the attention of urologists for both scientific and clinical reasons. The search for an explanation and the prediction of the variable behaviour of the malignant prostatic cell continues unabated. The search for more precise tumour staging and more effective treatment is equally vigorous. Editors Andrew Bruce and John Trachtenberg have assembled acknowledged leaders in prostate cancer to present those areas of direct interest to the clinician. There are a number of other topics that might have been considered but most of these, such as experimental tumour models or biochemical factors affecting cell growth, still lack immediate application for the clinician. Carcinoma of the prostate continues to have its highest incidence in the western world, and the difference in comparison with the incidence in the Far East appears to be real and not masked by diagnostic or other factors. A number of other epidemiological aspects need careful analysis: Is the incidence increasing? Is the survival improving? Is the prognosis worse in the younger patient? Epidemiological data are easily misused and misinterpreted so that a precise analysis of the known facts makes an important opening chapter to this book.

The Great Prostate Hoax

Author: Richard J. Ablin

Publisher: Macmillan

Published: 2014-03-04

Total Pages: 274

ISBN-13: 1137278749

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Reveals how fear-based and inaccurate testing is resulting in unnecessary high-risk surgeries, arguing that the PSA test was never intended for prostate cancer screening.

Prostate Cancer

Author: Leland W. K. Chung

Publisher: Springer Science & Business Media

Published: 2007-11-10

Total Pages: 512

ISBN-13: 1597452246

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Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, reviews new, valuable approaches to the treatment of prostate cancer in men. The latest edition contains new material on molecular imaging, new treatments for prostate cancer, molecular targets, cell signaling pathways, bioinformatics, and pathogenomics. The book details the latest innovations and advances in prostate cancer and may be used as a rapid reference text for readers. The volume profiles the latest advances in cancer research and treatment and includes profound studies in prostate stem cells, cancer-host interactions, hedgehog signaling in development and cancer, cholesterol and cell signaling, gene therapy for advanced prostate cancer, and noninvasive strategies such as molecular imaging to visualize gene expression. This new edition also investigates expression profiling and somatic alterations in prostate cancer progression and linkage studies of prostate cancer families to identify susceptibility genes. The issues of racial differences in prostate cancer mortality, radiotherapy for the treatment of locally advanced prostate cancer, recombinant antibody candidates for treatment, taxane-based chemotherapy, lethal phenotypes, and novel and efficient translation clinical trials are also presented in great depth. Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, provides readers with a general reference for prostate cancer from prevention to therapy and will be of value to clinicians, scientists, and administrators who strive to solve the cancer problem.

Prostate Cancer For Dummies

Author: Paul H. Lange

Publisher: John Wiley & Sons

Published: 2011-03-10

Total Pages: 380

ISBN-13: 1118053036

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Hearing that you have prostate cancer, or even that you may have it, is very scary. But this disease, in many cases, is curable. Even if you have advanced cancer that's spread beyond the prostate, many treatments help extend your life for years. You need good information to help you with the decisions that lie ahead, and this book provides you with this information. Prostate Cancer For Dummies can help you if You have prostate cancer (or you think that you have it), or someone close to you has it. You want information on treatments for prostate cancer as you form a treatment plan with your doctor. You are curious about alternative therapies for prostate cancer. You want to know what actions you can take over the long-term to continue to fight your prostate cancer. Prostate Cancer For Dummies explains the key issues and problems that are associated with prostate cancer, and assures you that although the initial impact of being diagnosed is devastating, you can take action to extend your life. You don't have to read this book from the first page straight on through, although you can. You may want to read the first chapter and then move to the chapters that affect you the most. In Prostate Cancer For Dummies, you'll gain insight into Discovering the key symptoms of prostate cancer Recognizing the risk factors, and who's most likely to have prostate cancer Getting a diagnosis, and what's involved Getting well again, and how you can work with your doctor to come up with a plan to cope with your cancer Changing your lifestyle to decrease your risk of a recurrence Coping with the aftermath, from temporary to permanent side effects Handling work and family, and how to help others understand what you're going through It's extremely hard to hear from your doctor that you or a loved one has prostate cancer. But after you recover from the initial shock of diagnosis, you need to educate yourself, and, with the help of your physician, make a plan for getting the best treatment possible. Prostate Cancer For Dummies will help you achieve these goals and encourage you to maintain your commitment to managing your health.