21st Century Challenges in Antimicrobial Therapy and Stewardship
21st Century Challenges in Antimicrobial Therapy and Stewardship

Author: Islam M Ghazi

Publisher:

Published: 2020-11-19

Total Pages: 492

ISBN-13: 9789811461828

DOWNLOAD EBOOK

21st Century Challenges in Antimicrobial Therapy and Stewardship addresses selected topics that are of importance in the practice of infectious disease management. The text starts by illustrating the global landscape of antimicrobial drug resistance, which influences antimicrobial use and therapeutic decisions in the clinic. The contributors explain the reasons for the spread of antibiotic resistance, the pharmacology of antibiotics of different classes, innovative drug delivery methods which can improve the efficacy and safety of new drug candidates and achieve targeted drug delivery as well as drug resistance monitoring techniques and issues in the practice of antimicrobial stewardship and infection control.Key Features: - 14 organized chapters on several aspects of antimicrobial therapy and stewardship- Introductory knowledge on global antimicrobial trends- Coverage of molecular basis of antimicrobial resistance in gram positive, gram negative and fungal microbes- Focused coverage on new developments in antimicrobial drug development, drug delivery, formulation and diagnostic tools- Information on unmet needs of patients and clinicians, including the treatment of difficult infections- Comprehensive coverage of issues in antimicrobial stewardship21st Century Challenges in Antimicrobial Therapy and Stewardship brings to readers - healthcare administrators, educators, pharmacists, clinicians and students, alike - the knowledge of the molecular basis of antimicrobial drug therapy, drug resistance in pathogens and current practices in antimicrobial stewardship programs. This knowledge, in turn, fosters an awareness among healthcare industry participants to collaborate in an interprofessional environment to combat multidrug resistanc

21st Century Challenges in Antimicrobial Therapy and Stewardship
21st Century Challenges in Antimicrobial Therapy and Stewardship

Author: Islam M. Ghazi

Publisher: Bentham Science Publishers

Published: 2020-11-19

Total Pages: 493

ISBN-13: 9811461813

DOWNLOAD EBOOK

21st Century Challenges in Antimicrobial Therapy and Stewardship addresses selected topics that are of importance in the practice of infectious disease management. The text starts by illustrating the global landscape of antimicrobial drug resistance, which influences antimicrobial use and therapeutic decisions in the clinic. The contributors explain the reasons for the spread of antibiotic resistance, the pharmacology of antibiotics of different classes, innovative drug delivery methods which can improve the efficacy and safety of new drug candidates and achieve targeted drug delivery as well as drug resistance monitoring techniques and issues in the practice of antimicrobial stewardship and infection control. Key Features: - 14 organized chapters on several aspects of antimicrobial therapy and stewardship - Introductory knowledge on global antimicrobial trends - Coverage of molecular basis of antimicrobial resistance in gram positive, gram negative and fungal microbes - Focused coverage on new developments in antimicrobial drug development, drug delivery, formulation and diagnostic tools - Information on unmet needs of patients and clinicians, including the treatment of difficult infections - Comprehensive coverage of issues in antimicrobial stewardship 21st Century Challenges in Antimicrobial Therapy and Stewardship brings to readers – healthcare administrators, educators, pharmacists, clinicians and students, alike – the knowledge of the molecular basis of antimicrobial drug therapy, drug resistance in pathogens and current practices in antimicrobial stewardship programs. This knowledge, in turn, fosters an awareness among healthcare industry participants to collaborate in an interprofessional environment to combat multidrug resistance.

Antimicrobial Stewardship, An Issue of Infectious Disease Clinics
Antimicrobial Stewardship, An Issue of Infectious Disease Clinics

Author: Pranita Tamma

Publisher: Elsevier Health Sciences

Published: 2014-06-28

Total Pages: 169

ISBN-13: 0323299415

DOWNLOAD EBOOK

This issue of Infectious Disease Clinics, edited by Sara Cosgrove, MD, Pranita Tamma, MD, and Arjun Srinvasan, MD, is devoted to Infection Prevention and Stewardship. Articles in this issue include Behavior Issues in Antimicrobial Stewardship; Research Methods and Measurement Approaches for Analyzing the Impact of Antimicrobial Stewardship Programs; The Role of the Microbiology Laboratory in Antimicrobial Stewardship; Antimicrobial Stewardship in Long Term Care Facilities; Antimicrobial Stewardship in the NICU; Antimicrobial Stewardship in Immuno-compromised Populations; Antimicrobial Stewardship in Community Hospitals/Lower Resources Settings; Antimicrobial Stewardship in the Outpatient Setting; Informatics and Antimicrobial Stewardship; Antimicrobial Stewardship Interventions; and Teaching and Education in Antimicrobial Stewardship.

Antimicrobial Stewardship
Antimicrobial Stewardship

Author: Matthew Laundy

Publisher: Oxford University Press

Published: 2016-08-25

Total Pages: 211

ISBN-13: 0191076589

DOWNLOAD EBOOK

Antimicrobial resistance (AMR) challenges the treatment of clinical infections. Despite the decline in infectious diseases mortality rates, infections are more difficult to eliminate or contain in the host, resulting in poorer outcomes to treatment, longer hospital inpatient stays, and increased mortality. Written by international experts in the field and supported by the review of the available evidence, including example case studies, Antimicrobial Stewardship provides a practical how-to guide on this growing area. Divided into three sections, the first sets the scene, looking at the key problems of antimicrobial resistance. Section two examines and identifies the key components of an antimicrobial stewardship program. Finally, the book explores specialist areas of antimicrobial stewardship ranging from antimicrobial pharmacokinetics and dynamics, to near patient testing, and infection biomarkers. Antimicrobial Stewardship will be a valuable and practical resource for infection trainees, as well as specialists from the medical, pharmacy, and nursing professions.

Mechanisms of antibiotic resistance
Mechanisms of antibiotic resistance

Author: Jun Lin

Publisher: Frontiers Media SA

Published: 2015-06-01

Total Pages: 226

ISBN-13: 2889195260

DOWNLOAD EBOOK

Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.

Antimicrobial Resistance in Developing Countries
Antimicrobial Resistance in Developing Countries

Author: Aníbal de J. Sosa

Publisher: Springer Science & Business Media

Published: 2009-10-08

Total Pages: 553

ISBN-13: 0387893709

DOWNLOAD EBOOK

Avoiding infection has always been expensive. Some human populations escaped tropical infections by migrating into cold climates but then had to procure fuel, warm clothing, durable housing, and crops from a short growing season. Waterborne infections were averted by owning your own well or supporting a community reservoir. Everyone got vaccines in rich countries, while people in others got them later if at all. Antimicrobial agents seemed at first to be an exception. They did not need to be delivered through a cold chain and to everyone, as vaccines did. They had to be given only to infected patients and often then as relatively cheap injectables or pills off a shelf for only a few days to get astonishing cures. Antimicrobials not only were better than most other innovations but also reached more of the world’s people sooner. The problem appeared later. After each new antimicrobial became widely used, genes expressing resistance to it began to emerge and spread through bacterial populations. Patients infected with bacteria expressing such resistance genes then failed treatment and remained infected or died. Growing resistance to antimicrobial agents began to take away more and more of the cures that the agents had brought.

Antibiotic Optimization
Antibiotic Optimization

Author: Robert C. Owens

Publisher: CRC Press

Published: 2004-11-04

Total Pages: 684

ISBN-13: 0203996925

DOWNLOAD EBOOK

This book focuses on topics ranging from the economics of drug-resistant infections and the management of antimicrobial use to new information on methods to optimize the selection, route of administration, dosing, and duration of antimicrobial therapies for common infections. In addition to offering ideas on studied programmatic approaches for judi

Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine
Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine

Author: National Academies Of Sciences Engineeri

Publisher: National Academies Press

Published: 2022-07-20

Total Pages:

ISBN-13: 9780309269452

DOWNLOAD EBOOK

The National Strategy for Combating Antibiotic Resistant Bacteria, published in 2014, sets out a plan for government work to mitigate the emergence and spread of resistant bacteria. Direction on the implementation of this strategy is provided in five-year national action plans, the first covering 2015 to 2020, and the second covering 2020 to 2025. Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine evaluates progress made against the national strategy. This report discusses ways to improve detection of resistant infections and estimate the risk to human health from environmental sources of resistance. In addition, the report considers the effect of agricultural practices on human and animal health and animal welfare and ways these practices could be improved, and advises on key drugs and diseases for which animal-specific test breakpoints are needed.

Challenges to Tackling Antimicrobial Resistance
Challenges to Tackling Antimicrobial Resistance

Author: Michael Anderson

Publisher: Cambridge University Press

Published: 2020-04-23

Total Pages: 273

ISBN-13: 1108799450

DOWNLOAD EBOOK

An accessible overview of the challenges in tackling AMR, and the economic and policy responses of the 'One Health' approach. It will appeal to policy-makers seeking to strengthen national and local polices tackling AMR, as well as students and academics who want an overview of the latest scientific evidence regarding effective AMR policies.

Antimicrobial Resistance
Antimicrobial Resistance

Author: World Health Organization

Publisher:

Published: 2014

Total Pages: 232

ISBN-13: 9789241564748

DOWNLOAD EBOOK

Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.