The annual International Symposium on Therapeutic Ultrasound is the main focus of the activities of the International Society for Therapeutic Ultrasound (ISTU). ISTU's goal is to increase and diffuse knowledge of therapeutic ultrasound to the scientific and medical community, and to facilitate the translation of therapeutic ultrasound techniques into the clinical arena for the benefit of patients worldwide. The Proceedings distill the best presentations of the symposia and provide a reference for new and experienced workers in the field.
This book highlights advances and prospects of a highly versatile and dynamic research field: Therapeutic ultrasound. Leading experts in the field describe a wide range of topics related to the development of therapeutic ultrasound (i.e., high intensity focused ultrasound, microbubble-assisted ultrasound drug delivery, low intensity pulsed ultrasound, ultrasound-sensitive nanocarriers), ranging from the biophysical concepts (i.e., tissue ablation, drug and gene delivery, neuromodulation) to therapeutic applications (i.e., chemotherapy, sonodynamic therapy, sonothrombolysis, immunotherapy, lithotripsy, vaccination). This book is an indispensable source of information for students, researchers and clinicians dealing with non-invasive image-guided ultrasound-based therapeutic interventions in the fields of oncology, neurology, cardiology and nephrology.
This book offers a systematic introduction to the engineering principles and techniques of cavitation in biomedicine on the basis of its physics and mechanism. Adopting an interdisciplinary approach, it covers areas of interest ranging from physics and engineering to the biological and medical sciences. Individual chapters introduce the fundamentals of cavitation, describe its characterization, control and imaging techniques, and present cavitation-enhanced thermal and mechanical effects and their applications. Intended as both a reference work for graduate students, and as a guide for scientists and engineers who work with cavitation in biomedicine, it provides a broad and solid foundation of knowledge. The aim is to bridge the different disciplines involved, and to promote cross-discipline research, thus encouraging innovations in the scientific research and engineering applications alike. Dr. Mingxi Wan is a professor at Department of Biomedical Engineering, Xi’an Jiao Tong University, Xi’an, Shaanxi, China; Dr. Yi Feng works at Department of Biomedical Engineering, Xi’an Jiao Tong University, Xi’an, Shaanxi, China; Dr. Gail ter Haar is a professor at The Institute of Cancer Research, Sutton, Surry, UK.
By integrating knowledge from pharmacology, microbiology, molecular medicine, and engineering, researchers from Europe, the U.S. and Asia cover a broad spectrum of current and potential antimicrobial medications and treatments. The result is a comprehensive survey ranging from small-molecule antibiotics to antimicrobial peptides and their engineered mimetics, from enzymes to nucleic acid therapeutics, from metallic nanoparticles to photo- and sonosensitizers and to phage therapy. In each case, the therapeutic approaches are compared in terms of their mechanisms, likelihood to induce resistance, and their efficiency in a global healthcare context. Unrivaled knowledge for professionals in fundamental research, pharmaceutical development and clinical practice.
Ultrasound has been widely used in diagnostic imaging for a long time. In the past 10 years, image-guided focused ultrasound therapy has seen rapid growth, in biomedical science and engineering, and in clinical medicine. The purpose of this book is to bring internationally renowned authorities and experts in this field together to provide up-to-date and comprehensive reviews of basic physics, biomedical engineering, and clinical applications of focused ultrasound therapy in a widely accessible fashion. Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of focused ultrasound therapy. It reviews the medical physics and bio-effects of focused ultrasound beams on living tissues, dosimetric methods and measurements, transducer engineering, image guidance and monitoring (including magnetic resonance imaging -- MRI -- and ultrasound), treatment delivery systems, and clinical applications. The book also gives practical guidelines on patient setup, target localisation, treatment planning and image-guided procedures for the treatment in various sites, including the prostate, liver, pancreas, breast, kidney, uterus, bone, and brain. The book discusses major challenges for the use of focused ultrasound energy on living tissues and explores the cellular and physiological responses that can be employed in the fight against cancer from biological, physics and engineering perspectives. It also highlights recent advances, including the treatment of solid tumours using image-guided drug delivery, and the exploitation of microbubbles, nanoparticles, and other cutting-edge techniques. Readers who are interested in learning more about the technique and the clinical applications described in each chapter can find more information in the comprehensive bibliographies provided. This book is suitable for anyone involved in, or looking to become involved in, the research and clinical applications of focused ultrasound therapy, including medical professionals, physicists, biomedical engineers, graduate students and others working in this multidisciplinary field. It offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and an outlook on the future of focused ultrasound therapy. It presents a thorough introduction for those new to the field while providing helpful, up-to-date information and guidelines for readers already using this therapy in clinical and pre-clinical settings. Key Features: Brings together a wide range of world-leading experts in this new field, presenting the latest clinical outcomes of using focused ultrasound for the treatment of benign and malignant diseases Covers the fundamental physics of focused ultrasound therapy and ultrasound-mediated drug delivery, including chapters on the mechanism of sonoporation, microbubble and ultrasound interaction, and their potential clinical applications Introduces clinical guidelines for focused ultrasound therapy, including indications and contraindications, treatment goals, the selection of patients, clinical observation during treatment procedure and follow-up, and characteristics of image changes after treatment
Diagnostic Ultrasound Imaging provides a unified description of the physical principles of ultrasound imaging, signal processing, systems and measurements. This comprehensive reference is a core resource for both graduate students and engineers in medical ultrasound research and design. With continuing rapid technological development of ultrasound in medical diagnosis, it is a critical subject for biomedical engineers, clinical and healthcare engineers and practitioners, medical physicists, and related professionals in the fields of signal and image processing. The book contains 17 new and updated chapters covering the fundamentals and latest advances in the area, and includes four appendices, 450 figures (60 available in color on the companion website), and almost 1,500 references. In addition to the continual influx of readers entering the field of ultrasound worldwide who need the broad grounding in the core technologies of ultrasound, this book provides those already working in these areas with clear and comprehensive expositions of these key new topics as well as introductions to state-of-the-art innovations in this field. - Enables practicing engineers, students and clinical professionals to understand the essential physics and signal processing techniques behind modern imaging systems as well as introducing the latest developments that will shape medical ultrasound in the future - Suitable for both newcomers and experienced readers, the practical, progressively organized applied approach is supported by hands-on MATLAB® code and worked examples that enable readers to understand the principles underlying diagnostic and therapeutic ultrasound - Covers the new important developments in the use of medical ultrasound: elastography and high-intensity therapeutic ultrasound. Many new developments are comprehensively reviewed and explained, including aberration correction, acoustic measurements, acoustic radiation force imaging, alternate imaging architectures, bioeffects: diagnostic to therapeutic, Fourier transform imaging, multimode imaging, plane wave compounding, research platforms, synthetic aperture, vector Doppler, transient shear wave elastography, ultrafast imaging and Doppler, functional ultrasound and viscoelastic models
Percutaneous renal procedures are highly complex and require a great deal of surgical skill. Improve your patient care with this outstanding instruction manual from the experts. Clinically-focused throughout, the three major conditions managed by percutaneous renal surgery – large renal calculi, transitional cell cancer and renal cell cancer – are expertly covered by the world’s leading surgeons and urologists. Well-illustrated with over 100 top-quality surgical photos and with reference to the leading society guidelines in this area, inside you’ll find coverage of: • Evidence-based outcomes for percutaneous management • Patient selection and informed consent • Preparing the patient for surgery • Instrumentation used in surgery • Surgical technique and patient safety • Pre-and post-op counseling In addition, 10 high-quality videos offer an excellent visual guide to best practice and surgical tips and tricks of the trade. Percutaneous Renal Surgery is the perfect multi-media teaching tool, providing urologists, nephrologists and surgeons with the knowledge, confidence and clinical skills required to perform these complex and difficult surgical procedures safely and effectively. Of related interest Smith’s Textbook of Endourology, 3rd edition, Smith, ISBN 9781444335545 Top Tips in Urology, 2nd edition, McLoughlin, ISBN 9780470672938
The general topic of the symposium follows mechanisms development through all stages of conception, modeling, analysis, synthesis and control to advanced product design. This volume brings together the latest results in the field and celebrates a series of conferences that has been running for 40 years. The contributors and the editor are world leaders in their field.
