TRAIL

TRAIL

Author:

Publisher: Elsevier

Published: 2004-07-06

Total Pages: 521

ISBN-13: 0080522874

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The discovery of TRAIL (TNF Related Apoptosis Inducing Ligand), also referred to as Apo-2, is in an era of intense research because TRAIL induces many cancer cells to undergo programmed cell death (apoptosis), while having no effect on normal cells. This important protein deserves extensive review at a formative time in the devlopement of our knowledge concerning its mechanism of action and the ways in which it can be used as a cancer chemotherapeutic agent. Consequently, this voume reviews the current status of research on TRAIL.Selected Contents:* Crystal Structure of RANK Ligand involved in bone metabolism* Promoter of TRAIL-R2 Gene* Monoclonal Antibodies against TRAIL* Modulation of TRAIL signaling complex* TRAIL in the airways* FLIP Protein and TRAIL-Induced Apoptosis* TRAIL and Ceramide* TRAIL and Viral Infection* TRAIL and Malignant Glioma


Analysis through Action for Actors and Directors

Analysis through Action for Actors and Directors

Author: David Chambers

Publisher: Taylor & Francis

Published: 2024-06-03

Total Pages: 329

ISBN-13: 1040025633

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Analysis through Action for Actors and Directors is a comprehensive view of an innovative and exciting process for making new theatre. As well as an understanding of how Analysis through Action has developed over time, this book also demonstrates how it can be put into practice in today’s theatre. The first part of this book traces the exciting genealogy from Stanislavsky’s unfinished experiments, through the insights of geniuses Maria Knebel and Georgii Tovstonogov, down to today’s avant-garde auteurs. The second part is a practical manual based on extensive field testing by the author and colleagues. Here, two key components of the process are elucidated: Text Actions – ten interwoven text analysis steps – to be twinned with the thrilling rehearsal process using focused and joyful improvisations called Études. Written for new or experienced theatre students and practitioners, this book will enrich the technique of any theatre artist and anyone else interested in the theatre and its future.


Quality of Drinking Water--1980

Quality of Drinking Water--1980

Author: United States. Congress. House. Committee on Interstate and Foreign Commerce. Subcommittee on Health and the Environment

Publisher:

Published: 1980

Total Pages: 744

ISBN-13:

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The Neuroscience of Cocaine

The Neuroscience of Cocaine

Author: Victor R Preedy

Publisher: Academic Press

Published: 2017-05-23

Total Pages: 776

ISBN-13: 012803792X

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The Neuroscience of Cocaine: Mechanisms and Treatment explores the complex effects of this drug, addressing the neurobiology behind cocaine use and the psychosocial and behavioral factors that impact cocaine use and abuse. This book provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms. Cocaine is one of the most highly abused illicit drugs worldwide and is frequently associated with other forms of drug addiction and misuse, but researchers are still struggling to understand cocaine's neuropharmacological profile and the mechanisms of its effects and manifestations at the cognitive level. Cessation of cocaine use can lead to numerous adverse withdrawal conditions, from the cellular and molecular level to the behavioral level of the individual user. Written by worldwide experts in cocaine addiction, this book assists neuroscientists and other addiction researchers in unraveling the many complex facets of cocaine use and abuse. - Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding - Illustrated in full color - Provides unique full coverage of all aspects of cocaine and its related pathology - Provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms


The Oxford Handbook of Sex Offences and Sex Offenders

The Oxford Handbook of Sex Offences and Sex Offenders

Author: Teela Sanders

Publisher: Oxford University Press

Published: 2017

Total Pages: 681

ISBN-13: 0190213639

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The Oxford Handbook on Sex Offenses and Sex Offenders provides comprehensive, even-handed analysis of the myriad of topics related to sex offenses, including pornography, sex trafficking, criminal justice responses, and the role of social media in sex crimes. Extending beyond the existing scholarly research on the topic, this volume teases out the key debates, controversies, and challenges involved in addressing sex crimes.


Henry V

Henry V

Author: Gwilym Dodd

Publisher: Boydell & Brewer Ltd

Published: 2013

Total Pages: 326

ISBN-13: 1903153468

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Fresh examinations of the activities of Henry V, looking at how his reputation was achieved.