Xenobiotics and the Gut Microbiome in Health and Disease
Author: Stephen J. Pandol
Publisher: Frontiers Media SA
Published: 2019-10-14
Total Pages: 191
ISBN-13: 288963082X
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The Chemistry of Microbiomes
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Published: 2017-07-19
Total Pages: 133
ISBN-13: 0309458390
DOWNLOAD EBOOKThe 21st century has witnessed a complete revolution in the understanding and description of bacteria in eco- systems and microbial assemblages, and how they are regulated by complex interactions among microbes, hosts, and environments. The human organism is no longer considered a monolithic assembly of tissues, but is instead a true ecosystem composed of human cells, bacteria, fungi, algae, and viruses. As such, humans are not unlike other complex ecosystems containing microbial assemblages observed in the marine and earth environments. They all share a basic functional principle: Chemical communication is the universal language that allows such groups to properly function together. These chemical networks regulate interactions like metabolic exchange, antibiosis and symbiosis, and communication. The National Academies of Sciences, Engineering, and Medicine's Chemical Sciences Roundtable organized a series of four seminars in the autumn of 2016 to explore the current advances, opportunities, and challenges toward unveiling this "chemical dark matter" and its role in the regulation and function of different ecosystems. The first three focused on specific ecosystemsâ€"earth, marine, and humanâ€"and the last on all microbiome systems. This publication summarizes the presentations and discussions from the seminars.
The Gut Microbiome in Health and Disease
Author: Dirk Haller
Publisher: Springer
Published: 2018-07-27
Total Pages: 355
ISBN-13: 3319905457
DOWNLOAD EBOOKThe book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.
Hormones and Resistance
Author: Hans Selye
Publisher: Springer Science & Business Media
Published: 2013-04-17
Total Pages: 1158
ISBN-13: 3642651925
DOWNLOAD EBOOK7 If so, the individual members of each class thus identified could then be subjected to a more profound pharmacokinetic analysis. In other words, we had to determine first which hormone protects against which drug, before we could explore how it did this. We had to know first that a hormone has adaptive value before we could ask whether this is due to a syntoxic or a catatoxic mechanism. Such observations, as the fact that an indomethacin-induced intestinal ulcer can be prevented by ethylestrenol, orthat cortisol aggravates certain infections, reveal nothing about how these hormones work; but only findings of this type can tell us where further research would be rewarding. Of course, scientists can rarely identify by direct observation the tbings that they are looking for; most of the time they have to be guided by indirect indices. The ebernist often first detects a compound, or even a particular functional group in its molecule, by inference from a color reaction, a revealing X-ray diffraction pattern or the formation of a characteristic precipitate. The physician must first suspect the presence of a microbe through certain clinical signs and symptoms before he can verify his diagnosis by looking for a particular organism. It is perhaps not too daring to hope that in our first efforts to clarify the role of hormones in resistance, simple, directly visible indicators might also serve us best.
Toxicology of the Gastrointestinal Tract, Second Edition
Author: Shayne Cox Gad
Publisher: CRC Press
Published: 2018-10-26
Total Pages: 477
ISBN-13: 042978144X
DOWNLOAD EBOOKNanoparticles as both potential unique risks and as a valuable approach to increased and higher specificity in delivery of therapeutics A primer on the largest, most diverse, and important microbiome in any mammal "Tricks of the trade" on modifying the oral administration of drugs
The Microbiome in Health and Disease
Author:
Publisher: Academic Press
Published: 2020-05-29
Total Pages: 524
ISBN-13: 0128200014
DOWNLOAD EBOOKThe Microbiome in Health and Disease, Volume 171 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Microbiome in health and disease, CNS development and microbiome in infants, A gut feeling in ALS, Microbiome (Virome) and virus infection, Bugs and Drugs: microbiome in medicine metabolism, Immunity, T cells, and microbiome, Salmonella (Bacterial) infection and cancer: of mice and men, and many other highly researched topics. Provides a novel theme and multiple disciplinary topics of microbiome research in basic and translational studies Presents an updated collection on bacteria, virus, fungi and their interactions in microbiome Includes a timely discussion on the tools and methods used for modeling and analysis of microbiome data
Diet-Microbe Interactions in the Gut
Author: Kieran Tuohy
Publisher: Academic Press
Published: 2014-08-04
Total Pages: 268
ISBN-13: 0124079415
DOWNLOAD EBOOKDrawing on expert opinions from the fields of nutrition, gut microbiology, mammalian physiology, and immunology, Diet-Microbe Interactions for Human Health investigates the evidence for a unified disease mechanism working through the gut and its resident microbiota, and linking many inflammation-related chronic diet associated diseases. State of the art post-genomic studies can highlight the important role played by our resident intestinal microbiota in determining human health and disease. Many chronic human diseases associated with modern lifestyles and diets — including those localized to the intestinal tract like inflammatory bowel disease and celiac disease, and more pervasive systemic conditions such as obesity, diabetes and cardiovascular disease — are characterized by aberrant profiles of gut bacteria or their metabolites. Many of these diseases have an inflammatory basis, often presenting with a chronic low-grade systemic inflammation, hinting at persistent and inappropriate activation of inflammatory pathways. Through the presentation and analysis of recent nutrition studies, this book discusses the possible mechanisms underpinning the disease processes associated with these pathologies, with high fat diets appearing to predispose to disease, and biologically active plant components, mainly fiber and polyphenols, appearing to reduce the risk of chronic disease development. - One comprehensive, translational source for all aspects of nutrition and diet's effect on gastrointestinal health and disease - Experts in nutrition, diet, microbiology and immunology take readers from the bench research (cellular and biochemical mechanisms of vitamins and nutrients) to new preventive and therapeutic approaches - Clear presentations by leading researchers of the cellular mechanisms underlying diet, immune response, and gastrointestinal disease help practicing nutritionists and clinicians (gastroenterologists, endocrinologists) map out new areas for clinical research and structuring clinical recommendations
Environmental Chemicals, the Human Microbiome, and Health Risk
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Published: 2018-03-01
Total Pages: 123
ISBN-13: 0309468698
DOWNLOAD EBOOKA great number of diverse microorganisms inhabit the human body and are collectively referred to as the human microbiome. Until recently, the role of the human microbiome in maintaining human health was not fully appreciated. Today, however, research is beginning to elucidate associations between perturbations in the human microbiome and human disease and the factors that might be responsible for the perturbations. Studies have indicated that the human microbiome could be affected by environmental chemicals or could modulate exposure to environmental chemicals. Environmental Chemicals, the Human Microbiome, and Health Risk presents a research strategy to improve our understanding of the interactions between environmental chemicals and the human microbiome and the implications of those interactions for human health risk. This report identifies barriers to such research and opportunities for collaboration, highlights key aspects of the human microbiome and its relation to health, describes potential interactions between environmental chemicals and the human microbiome, reviews the risk-assessment framework and reasons for incorporating chemicalâ€"microbiome interactions.
Microbes and the Mind
Author: C.S.M. Cowan
Publisher: Karger Medical and Scientific Publishers
Published: 2021-05-06
Total Pages: 158
ISBN-13: 331806856X
DOWNLOAD EBOOKInterest in the mind-body connection has grown in recent years, with accumulating evidence showing that the gut microbiome can alter behavioral, neural, and psychological outcomes. This publication brings together a group of international experts who are investigating the microbiome and its potential to contribute to the causes and treatment of mental illness. The contributions are not aimed solely at specialists in clinical and experimental neuroscience. They cover a range of key topics, including the role of the microbiome in mental health and specific psychiatric disorders that occur across the lifespan, interactions with the immune system, diet, and pharmacological interventions. Furthermore, the microbial metabolite production and the potential for psychobiotic interventions that target the microbiome to improve mental health outcomes are discussed. This book is unique in its focus on the mechanisms and consequences of the activities of gut microorganisms in mental health and illness, providing expert insight into the current state of the art and important future directions for this emerging area of research. Additionally, it provides an excellent knowledge base for newcomers and a refresher for researchers and clinicians working in the fields of neuroscience, psychology, or psychiatry.
Parasitology and Microbiology Research
Author: Gilberto Antonio Bastidas Pacheco
Publisher: BoD – Books on Demand
Published: 2020-06-17
Total Pages: 376
ISBN-13: 1789859018
DOWNLOAD EBOOKThe study of both unicellular and multicellular living beings and the diseases they produce from a biological point of view requires constant review of their relationship with their host and environment, given their indisputable sanitary importance. In this sense, in parasitology and microbiology, updated and concise information on life cycle, taxonomic classification, clinical manifestations, diagnosis, treatment, epidemiological behavior, and control measures is of vital importance. This is what we pursue with this book. The approach to parasitology and microbiology and the research that is carried out on it is unquestionable because the associations between life forms have been present from the very beginning of life.Research in parasitology and microbiology is necessary and indispensable for controlling diseases that affect much of the world with serious economic and social consequences. The challenge is to promote research to keep these diseases at bay. This book shows what has been done up to now and what can be done in the future to combat infectious diseases.
