The Neural Control of Movement

The Neural Control of Movement

Author: Patrick J. Whelan

Publisher: Academic Press

Published: 2020-08-31

Total Pages: 484

ISBN-13: 0128164778

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From speech to breathing to overt movement contractions of muscles are the only way other than sweating whereby we literally make a mark on the world. Locomotion is an essential part of this equation and exciting new developments are shedding light on the mechanisms underlying how this important behavior occurs. The Neural Control of Movement discusses these developments across a variety of species including man. The editors focus on highlighting the utility of different models from invertebrates to vertebrates. Each chapter discusses how new approaches in neuroscience are being used to dissect and control neural networks. An area of emphasis is on vertebrate motor networks and particularly the spinal cord. The spinal cord is unique because it has seen the use of genetic tools allowing the dissection of networks for over ten years. This book provides practical details on model systems, approaches, and analysis approaches related to movement control. This book is written for neuroscientists interested in movement control. Provides practice details on model systems, approaches, and analysis approaches related to movement control Discusses how recent advances like optogenetics and chemogenetics affect the need for model systems to be modified (or not) to work for studies of movement and motor control Written for neuroscientists interested in movement control, especially movement disorders like Parkinson's, MS, spinal cord injury, and stroke


The Neural Control of Movement

The Neural Control of Movement

Author: Patrick J. Whelan

Publisher: Academic Press

Published: 2020-08-12

Total Pages: 486

ISBN-13: 0128172754

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From speech to breathing to overt movement contractions of muscles are the only way other than sweating whereby we literally make a mark on the world. Locomotion is an essential part of this equation and exciting new developments are shedding light on the mechanisms underlying how this important behavior occurs. The Neural Control of Movement discusses these developments across a variety of species including man. The editors focus on highlighting the utility of different models from invertebrates to vertebrates. Each chapter discusses how new approaches in neuroscience are being used to dissect and control neural networks. An area of emphasis is on vertebrate motor networks and particularly the spinal cord. The spinal cord is unique because it has seen the use of genetic tools allowing the dissection of networks for over ten years. This book provides practical details on model systems, approaches, and analysis approaches related to movement control. This book is written for neuroscientists interested in movement control. - Provides practice details on model systems, approaches, and analysis approaches related to movement control - Discusses how recent advances like optogenetics and chemogenetics affect the need for model systems to be modified (or not) to work for studies of movement and motor control - Written for neuroscientists interested in movement control, especially movement disorders like Parkinson's, MS, spinal cord injury, and stroke


Peripheral and Spinal Mechanisms in the Neural Control of Movement

Peripheral and Spinal Mechanisms in the Neural Control of Movement

Author: M.D. Binder

Publisher: Elsevier

Published: 1999-12-17

Total Pages: 499

ISBN-13: 0080862489

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In the last decade, we have witnessed a striking maturation of our understanding of how neurons in the spinal cord control muscular activity and movement. Paradoxically, a host of new findings have revealed an unexpected versatility in the behavior of these well-studied neural elements and circuits. In this volume, the world's leading experts review the current state of our knowledge of motor control, outline their latest results and developments, and delineate the seminal unresolved questions in this vibrant field of research. The volume begins with a commentary and overview of our current understanding of the peripheral and spinal basis of motor control. The remainder of the volume is divided into seven sections, each focused on a different problem. The first chapter in each section provides some historical review and presages the experimental findings and hypotheses that are discussed in subsequent chapters.Topics include the biomechanics of neuromuscular systems, the properties of motoneurons and the muscle units they control, spinal interneurons, pattern generating circuits, locomotion, descending control of spinal circuits, comparative physiology of motor systems, and motor systems neurophysiology studied in man. The book serves as a unique reference volume and should be essential reading for anyone interested in motor systems. Moreover, the volume's comprehensive coverage of a wide range of topics make it an effective textbook for graduate level courses in motor control neurobiology, kinesiology, physical therapy, and rehabilitation medicine.


Classics in Movement Science

Classics in Movement Science

Author: Mark L. Latash

Publisher: Human Kinetics

Published: 2001

Total Pages: 472

ISBN-13: 9780736000284

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Classics in Movement Science begins with a through and provocative introductory chapter on the beginnings of movement science, which sets the stage for the rest of the book. It presents 13 classical papers from famous scientists.


Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

Author: National Research Council

Publisher: National Academies Press

Published: 2003-08-22

Total Pages: 223

ISBN-13: 030916785X

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Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.


Neurons, Networks, and Motor Behavior

Neurons, Networks, and Motor Behavior

Author: Paul S. G. Stein

Publisher: MIT Press

Published: 1997

Total Pages: 330

ISBN-13: 9780262692274

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Recent advances in motor behavior research rely on detailed knowledge of the characteristics of the neurons and networks that generate motor behavior. At the cellular level, Neurons, Networks, and Motor Behavior describes the computational characteristics of individual neurons and how these characteristics are modified by neuromodulators. At the network and behavioral levels, the volume discusses how network structure is dynamically modulated to produce adaptive behavior. Comparisons of model systems throughout the animal kingdom provide insights into general principles of motor control. Contributors describe how networks generate such motor behaviors as walking, swimming, flying, scratching, reaching, breathing, feeding, and chewing. An emerging principle of organization is that nervous systems are remarkably efficient in constructing neural networks that control multiple tasks and dynamically adapt to change.The volume contains six sections: selection and initiation of motor patterns; generation and formation of motor patterns: cellular and systems properties; generation and formation of motor patterns: computational approaches; modulation and reconfiguration; short-term modulation of pattern generating circuits; and sensory modification of motor output to control whole body orientation.