Women in Experimental Pharmacology and Drug Discovery Pharmacology 2023
Women in Experimental Pharmacology and Drug Discovery Pharmacology 2023

Author: Patricia Rijo

Publisher: Frontiers Media SA

Published: 2024-07-24

Total Pages: 147

ISBN-13: 2832552080

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At present, according to UNESCO, less than 30% of researchers worldwide are women. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and STEM research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers.

Sex and Gender Differences in Pharmacology
Sex and Gender Differences in Pharmacology

Author: Vera Regitz-Zagrosek

Publisher: Springer Science & Business Media

Published: 2012-10-02

Total Pages: 599

ISBN-13: 3642307264

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This is the very first book to deal with sex and gender differences in drug therapy - an increasingly recognized medical need. It starts with an overview on S/G in clinical syndromes and a documentation of the medical and socioeconomic damage caused by gender specific adverse drug effects. Part I covers S/G differences in pharmacokinetics. Researchers will be satisfied by the detailed discussion of the mechanisms of S/G differences in drug effects that represents cutting edge science and includes interaction of drugs with sex hormones, genomic and epigenetic mechanisms. It also covers S/G in drug development, in animal models and clinical development and S/G in drug prescriptions. Part II targets S/G differences in drug effects in cardiovascular, pulmonary, CNS, neuromuscular, neuropsychiatric and metabolic diseases, in cancer, inflammation, and rheumatic diseases, in bacterial and retroviral infections, thrombosis, embolism. New drugs will be discussed.

Concepts and Principles of Pharmacology
Concepts and Principles of Pharmacology

Author: James E. Barrett

Publisher: Springer Nature

Published: 2019-12-24

Total Pages: 457

ISBN-13: 3030353621

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Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.

Re-emergence of Natural Products for Drug Discovery in Honor of Prof. Dr. M. Iqbal Choudhary
Re-emergence of Natural Products for Drug Discovery in Honor of Prof. Dr. M. Iqbal Choudhary

Author: Hidayat Hussain

Publisher: Frontiers Media SA

Published: 2024-02-29

Total Pages: 191

ISBN-13: 2832530206

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This Research Topic will honor Prof. M. Iqbal Choudhary for his pioneering contribution in the field of Bioorganic, Synthetic, and Natural Product Chemistry. Prof. M. Iqbal Choudhary is Director and Professor of Bioorganic and Natural Product Chemistry at the International Center for Chemical and Biological Sciences (H. E. J. Research Institute of Chemistry and Dr. Panjwani Center for Molecular Medicine and Drug Research), Pakistan and Coordinator General COMSTECH. Since 1990, Prof. Choudhary has been among the world leaders in the field of natural product chemistry, and has made pioneering contributions in the discovery of novel natural products. Prof. Choudhary has 1,212 publications (cumulative impact of > 2500) with 33,550 citations (h index 76) in the fields of organic and bioorganic chemistry. He also published 94 patents (64 US Patents), 90 books and 40 chapters in books, published by major U.S. and European presses. He discovered many potent anti-epileptic and anti-leishmanial compounds from indigenous medicinal plants that are under clinical trials. His contributions to reverse bacterial resistance to antibiotics represent seminal contributions in this important field. He has trained hundreds of young researchers, especially women, from across the Afro-Asian region in natural product chemistry and established several research centers in Pakistan, and helped to setup research units in Africa, and South and Central Asia. His scientific contributions have been recognized by prestigious national and international awards and honors, and fellowships of several academies of science.

Sex and Gender Effects in Pharmacology
Sex and Gender Effects in Pharmacology

Author: Stella E. Tsirka

Publisher: Springer Nature

Published: 2023-11-12

Total Pages: 286

ISBN-13: 3031426487

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Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the diagnosis and treatment of diseases affecting men and women, as well as of disease states that disproportionally affects women. Experts in various fields discuss both preclinical and clinical research that is contributing to a better understanding of the impact of sex in the presentation, etiology, treatment, and disease outcomes. Also discussed are the challenges encountered in implementing this growing body of knowledge into practice, as well as possible avenues to recognize and reduce health disparities between men and women so that therapeutic interventions are tailored and improved.

Basic and Clinical Pharmacology
Basic and Clinical Pharmacology

Author: Bertram G. Katzung

Publisher:

Published: 2001

Total Pages: 1217

ISBN-13: 9780071179683

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This best selling book delivers the most current, complete, and authoritative pharmacology information to students and practitioners. All sections are updated with new drug information and references. New! Many new figures and diagrams, along with boxes of highlighted material explaining the "how and why" behind the facts.

Observation and Experiment
Observation and Experiment

Author: Paul Rosenbaum

Publisher: Harvard University Press

Published: 2017-08-14

Total Pages: 395

ISBN-13: 067497557X

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A daily glass of wine prolongs life—yet alcohol can cause life-threatening cancer. Some say raising the minimum wage will decrease inequality while others say it increases unemployment. Scientists once confidently claimed that hormone replacement therapy reduced the risk of heart disease but now they equally confidently claim it raises that risk. What should we make of this endless barrage of conflicting claims? Observation and Experiment is an introduction to causal inference by one of the field’s leading scholars. An award-winning professor at Wharton, Paul Rosenbaum explains key concepts and methods through lively examples that make abstract principles accessible. He draws his examples from clinical medicine, economics, public health, epidemiology, clinical psychology, and psychiatry to explain how randomized control trials are conceived and designed, how they differ from observational studies, and what techniques are available to mitigate their bias. “Carefully and precisely written...reflecting superb statistical understanding, all communicated with the skill of a master teacher.” —Stephen M. Stigler, author of The Seven Pillars of Statistical Wisdom “An excellent introduction...Well-written and thoughtful...from one of causal inference’s noted experts.” —Journal of the American Statistical Association “Rosenbaum is a gifted expositor...an outstanding introduction to the topic for anyone who is interested in understanding the basic ideas and approaches to causal inference.” —Psychometrika “A very valuable contribution...Highly recommended.” —International Statistical Review

Pharmacology
Pharmacology

Author: Karen Whalen

Publisher: LWW

Published: 2018-06-25

Total Pages: 0

ISBN-13: 9781496384133

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"Lippincott Illustrated Reviews: Pharmacology, Seventh Edition, is the updated, enhanced version of the student-favorite resource for essentials of medical pharmacology. The first-and-best resource, the Lippincott Illustrated Reviews series features clear, effective writing and hundreds of illustrations for ideal rapid review and the assimilation of complex information. Clear, sequential images present mechanisms of action and focus on showing rather than telling students how drugs work. Nearly 600 annotated, full-color illustrations visually explain complex processes! Outline format ideal for concise review and foundational learning"--

Network Pharmacology
Network Pharmacology

Author: Shao Li

Publisher: Springer Nature

Published: 2021-09-29

Total Pages: 480

ISBN-13: 9811607532

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This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.

Regenerative Pharmacology
Regenerative Pharmacology

Author: George J. Christ

Publisher: Cambridge University Press

Published: 2013-04-15

Total Pages: 361

ISBN-13: 0521899494

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A state-of-the-art primer on the role of pharmacological sciences in regenerative medicine, for advanced students, postdoctoral fellows, and researchers.