Cerebrospinal Fluid (CSF) Proteomics

Cerebrospinal Fluid (CSF) Proteomics

Author: Enrique Santamaría

Publisher: Humana

Published: 2019-08-21

Total Pages: 557

ISBN-13: 9781493997053

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This volume focuses on protein analysis, including a wide range of the use of mass spectrometry and other protein methods within neurobiological disciplines. Chapters cover topics such as cerebrospinal fluid (CSF) processing and biobanking; label-free quantitative proteomics; SWATH; top-down proteomics; and experimental strategies based on other –omics applied to CSF metabolome, lipidome, and microRNAome. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Cerebrospinal Fluid (CSF) Proteomics: Methods and Protocols is a valuable resource for graduate students and post-doctoral fellows interested in learning more about CSF proteotyping. It is also useful to established researchers seeking further insight into this growing field.


Word Knowledge and Word Usage

Word Knowledge and Word Usage

Author: Vito Pirrelli

Publisher: Walter de Gruyter GmbH & Co KG

Published: 2020-04-20

Total Pages: 621

ISBN-13: 3110432447

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Word storage and processing define a multi-factorial domain of scientific inquiry whose thorough investigation goes well beyond the boundaries of traditional disciplinary taxonomies, to require synergic integration of a wide range of methods, techniques and empirical and experimental findings. The present book intends to approach a few central issues concerning the organization, structure and functioning of the Mental Lexicon, by asking domain experts to look at common, central topics from complementary standpoints, and discuss the advantages of developing converging perspectives. The book will explore the connections between computational and algorithmic models of the mental lexicon, word frequency distributions and information theoretical measures of word families, statistical correlations across psycho-linguistic and cognitive evidence, principles of machine learning and integrative brain models of word storage and processing. Main goal of the book will be to map out the landscape of future research in this area, to foster the development of interdisciplinary curricula and help single-domain specialists understand and address issues and questions as they are raised in other disciplines.


The Endocrine System in Sports and Exercise

The Endocrine System in Sports and Exercise

Author: William J. Kraemer

Publisher: John Wiley & Sons

Published: 2008-04-15

Total Pages: 648

ISBN-13: 0470757809

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This valuable new addition to the Encyclopaedia of Sports Medicine series provides a comprehensive and logical look at the principles and mechanisms of endocrinology as related to sports and exercise. It looks at growth hormone factors involved in exercise and the endocrinology of sport competition. It considers various factors and stresses on the body that may alter sporting performance. It covers topics from the acute responses and chronic adaptations of the human endocrine system to the muscular activity involved in conditioning exercise, physical labor, and sport activities. This book is an essential reference for helping to plan better programs of physical fitness, to prepare for sports competitions, and to manage the medical care of athletes.


Pathologic Myopia

Pathologic Myopia

Author: Richard F. Spaide

Publisher: Springer Nature

Published: 2021-07-28

Total Pages: 461

ISBN-13: 3030743349

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Pathologic Myopia is a major cause of severe vision loss worldwide. The mechanisms for vision loss include cataract, glaucoma, retinal detachment, and above all, myopic maculopathy within the posterior staphyloma. The first edition of Pathologic Myopia is one of the only current books to specifically address this disease and discusses recent developments in imaging technologies and various approaches to treatments, such as laser photocoagulation, photodynamic therapy, pharmaco-therapeutic injections in the vitreous, and surgery. This new edition is a timely update to the standard reference in the field, with new chapters on advanced refractive error correction, genetics, developing a classification system, and special surgical approaches for pathologic myopia. Complete with even more high-quality color images and informative tables, this book is written and edited by leaders in the field and is geared towards ophthalmologists, including residents and fellows in training, glaucoma and cataract specialists, and vitreoretinal macula experts.