Ureases
Ureases

Author: Rodrigo Ligabu Braun

Publisher: Elsevier

Published: 2024-02-16

Total Pages: 483

ISBN-13: 0323972004

DOWNLOAD EBOOK

Ureases: Foundations, Classes, and Applications provides a thorough, practical analysis of ureases—enzymes of growing relevance across a range of biotechnological applications and drug discovery. Unique in many aspects, ureases are one of the few enzymes to have nickel in their active sites. Ureases covers all aspects of this enzymatic class. Starting with foundational overview, the book discusses historical urease research and the current state, from basic biochemistry to the use of ureases as hallmarks in enzymology, crystallography, and bioinorganic chemistry. The different classes of ureases, structurally diverse but chemically equivalent, are individually discussed. The multi-protein, multi-step activation of ureases (with chemical modification of residues, transport, and transfer of nickel ions) are examined in-depth, along with the catalytic mechanisms of ureolysis and its inhibitors. The final two sections of the book address multiple applications of ureases in health and biotechnology, respectively, going from gastric ulcer treatment to architectural uses in buildings and engineering. Future applications and next steps in research are also considered. - Considers fundamental aspects of urease biochemistry, ureolysis and urease inhibitors - Discusses urease research across a range of applications, from drug discovery to biosensors, water purification, architecture and the food industry - Features chapter contributions from international leaders in the field

Encyclopedia of Metalloproteins
Encyclopedia of Metalloproteins

Author: Robert H. Kretsinger

Publisher: Springer

Published: 2013-05-01

Total Pages: 0

ISBN-13: 9781461415329

DOWNLOAD EBOOK

In biochemistry, a metalloprotein is a generic term for a protein that contains a metal cofactor. The metal may be an isolated ion or may be coordinated with a nonprotein organic compound, such as the porphyrin found in hemoproteins. In some cases, the metal is co-coordinated with a side chain of the protein and an inorganic nonmetallic ion. This kind of protein-metal-nonmetal structure is seen in iron-sulfur clusters Metalloproteins deals with all aspects related to the intracellular and extracellular metal-binding proteins, including their structures, properties and functions. The biological roles of metal cations and metal-binding proteins are endless. They are involved in all crucial cellular activities. Many pathological conditions are related to the problematic metal metabolism. Research in metalloprotein-related topics is therefore rapidly growing, and different aspects of metal-binding proteins progressively enter curricula at Universities and even at the High School level on occasion. However, no key resource providing basic, but comprehensible knowledge on this rapidly expanding field exists. The Encyclopedia of Metalloproteins aims to bridge this gap, and will attempt to cover various aspects of metalloprotein/metalloproteomics and will deal with the different issues related to the intracellular and extracellular metal-binding proteins, including their structures, properties and functions. The goal is to cover exhaustively all catalytically and biologically crucial metal ions and to find at least one interacting protein for other metal ions. The Encyclopedia of Metalloproteins will provide a key resource for advanced undergraduate and graduate students, researchers, instructors, and professors interested in protein science, biochemistry, cell biology, and genetics.

The Biological Chemistry of Nickel
The Biological Chemistry of Nickel

Author: Deborah Zamble

Publisher: Royal Society of Chemistry

Published: 2017-03-24

Total Pages: 396

ISBN-13: 1788010582

DOWNLOAD EBOOK

Metal ions play key roles in biology. Many are essential for catalysis, for electron transfer and for the fixation, sensing, and metabolism of gases. Others compete with those essential metal ions or have toxic or pharmacological effects. This book is structured around the periodic table and focuses on the control of metal ions in cells. It addresses the molecular aspects of binding, transport and storage that ensure balanced levels of the essential elements. Organisms have also developed mechanisms to deal with the non-essential metal ions. However, through new uses and manufacturing processes, organisms are increasingly exposed to changing levels of both essential and non-essential ions in new chemical forms. They may not have developed defenses against some of these forms (such as nanoparticles). Many diseases such as cancer, diabetes and neurodegeneration are associated with metal ion imbalance. There may be a deficiency of the essential metals, overload of either essential or non-essential metals or perturbation of the overall natural balance. This book is the first to comprehensively survey the molecular nature of the overall natural balance of metal ions in nutrition, toxicology and pharmacology. It is written as an introduction to research for students and researchers in academia and industry and begins with a chapter by Professor R J P Williams FRS.

Basic Techniques in Biochemistry, Microbiology and Molecular Biology
Basic Techniques in Biochemistry, Microbiology and Molecular Biology

Author: Aakanchha Jain

Publisher: Humana

Published: 2021-03-14

Total Pages: 282

ISBN-13: 9781493998630

DOWNLOAD EBOOK

This book presents key methodologies, tools and databases for biochemistry, microbiology and molecular biology in simple and straightforward language. Covering all aspects related to experimental principles and procedures, the protocols included here are brief and clearly defined, and include essential precautions to be taken while conducting experiments. The book is divided into two major sections: one on constructing, working with, and standard operating procedures for laboratory instruments; and one on practical procedures used in molecular biology, microbiology and biochemical analysis experiments, which are described in full. Each chapter describes both the basic theory and relevant practical details for a given experiment, and helps readers recognize both the experiment’s potential and limitations. Intended as an intensive introduction to the various tools used in molecular biology, the book covers all basic methods and equipment, including cloning, PCR, spectrophotometers, ELISA readers, sonicators, etc. As such, it offers a valuable asset for final year undergraduate (especially project) students, graduate research students, research scientists and technicians who wish to understand and employ new techniques in the field of biotechnology.

Soil Organic Matter and Biological Activity
Soil Organic Matter and Biological Activity

Author: D. Vaughan

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 475

ISBN-13: 9400951051

DOWNLOAD EBOOK

It has long been recognized that soil organic matter is the key to soil fertility. As a nutrient store it gradually provides essential elements which the soil cannot retain for long in inorganic form. It buffers growing plants against sudden changes in their chemical environment and preserves moisture in times of drought. It keeps the soil in a friable, easily penetrated physical condition, well-aerated and free draining, providing young seedlings with an excellent medium for growth. But it has another property, the nature and extent of which have been the subject of argu ment and controversy ever since scientists began to study the soil, and that is its ability to affect growth directly, other than by providing nutrient elements. Any one wishing to learn about these effects has been faced with a daunting mass of literature, some confusing, often contradictory, and spread through a multitude of journals. Individual aspects have been covered from time to time in reviews but there has obviously been a need for a modern authoritative text book dealing with the many facets of this subject, so the publication of this volume is timely. The editors and authors are all specialists in their fields, fully familiar with the com plex nature of soil organic matter and with the particular difficulties arising in any study of its properties. Where controversies exist they have presented all sides of the argument and have highlighted areas where further work is badly needed.

International Review of Cytology
International Review of Cytology

Author:

Publisher: Academic Press

Published: 1993-06-07

Total Pages: 345

ISBN-13: 008058683X

DOWNLOAD EBOOK

International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Natural Molecules in Neuroprotection and Neurotoxicity
Natural Molecules in Neuroprotection and Neurotoxicity

Author: Marcos Roberto de Oliveira

Publisher: Elsevier

Published: 2023-12-22

Total Pages: 2202

ISBN-13: 0443237646

DOWNLOAD EBOOK

Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells. This book is organized into four sections that address molecular mechanism underlying neuroprotection and neurotoxicity, neuroprotection mediated by natural molecules, neurotoxicity induced by natural compounds and nanotechnology-related strategies utilized in neuroprotection. Written by well-known researchers all over the world, chapters provide an in-depth analysis of numerous molecules, such as algae, plant and fungus-derived molecules, and comprehensively discuss their mechanisms of action and possible clinical applications. This book provides an essential reference for researchers and clinical scientists interested in the effects of natural compounds on the human health and disease. - Covers both neuroprotective and neurotoxic outcomes resulted from the exposure of brain cells to natural molecules - Analyzes numerous natural compounds, including animal, vegetal, fungal, bacterial, and marine-derived molecules - Discusses the effects of the metabolism of microbiota on the biotransformation of natural molecules and the consequences of these processes on brain cells - Contains a section focused on the nanotechnology-related strategies utilized to enhance the bioavailability of natural molecules to brain cells

Progress in Botany Vol. 81
Progress in Botany Vol. 81

Author: Francisco M. Cánovas

Publisher: Springer Nature

Published: 2020-01-23

Total Pages: 407

ISBN-13: 3030363279

DOWNLOAD EBOOK

With one volume each year, this series keeps scientists and advanced students informed of the latest developments and results in all areas of the plant sciences. The present volume includes reviews on plant physiology, biochemistry, genetics and genomics, forests, and ecosystems.

Methods to Determine Enzymatic Activity
Methods to Determine Enzymatic Activity

Author: Alane Beatriz Vermelho

Publisher: Bentham Science Publishers

Published: 2013-11-22

Total Pages: 334

ISBN-13: 1608053008

DOWNLOAD EBOOK

Methods to Determine Enzymatic Activity is a textbook about industrial enzymes. The book features definitions, classifications and applications of selected enzymes important in industry and in biotechnological processes. Analytical methods for these enzymes are also included in the text. The main objective of this textbook is to provide readers information focused on the current analysis methods of enzymatic activity at qualitative and quantitative levels. Each chapter is about one specific enzyme and contains information about its substrate and some biochemical properties. The methodologies are presented as an experimental protocol allowing interested readers to reproduce the experimental methods detailed within the textbook. These protocols contain the principle of the technique, materials, methods, and all steps necessary for the determination of enzyme activity and interpretation of results. Each methodology is illustrated with photos and schemes for a better and clear understanding. This book, therefore, uniquely brings modern analysis techniques of industrial enzymes in a single easy to understand volume. This textbook is suitable for undergraduate enzymology courses and advanced industrial biotechnology and microbiology courses.

A Comprehensive Survey of International Soybean Research - Genetics, Physiology, Agronomy and Nitrogen Relationships
A Comprehensive Survey of International Soybean Research - Genetics, Physiology, Agronomy and Nitrogen Relationships

Author: James E. Board

Publisher:

Published: 2013

Total Pages: 626

ISBN-13: 9789535142591

DOWNLOAD EBOOK

Soybean is the most important oilseed and livestock feed crop in the world. These dual uses are attributed to the crop's high protein content (nearly 40% of seed weight) and oil content (approximately 20%); characteristics that are not rivaled by any other agronomic crop. Across the 10-year period from 2001 to 2010, world soybean production increased from 168 to 258 million metric tons (54% increase). Against the backdrop of soybean's striking ascendancy is increased research interest in the crop throughout the world. Information in this book presents a comprehensive view of research efforts in genetics, plant physiology, agronomy, agricultural economics, and nitrogen relationships that will benefit soybean stakeholders and scientists throughout the world. We hope you enjoy the book.