Unsupervised Feature Extraction Applied to Bioinformatics

Unsupervised Feature Extraction Applied to Bioinformatics

Author: Y-h. Taguchi

Publisher: Springer Nature

Published: 2019-08-23

Total Pages: 329

ISBN-13: 3030224562

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This book proposes applications of tensor decomposition to unsupervised feature extraction and feature selection. The author posits that although supervised methods including deep learning have become popular, unsupervised methods have their own advantages. He argues that this is the case because unsupervised methods are easy to learn since tensor decomposition is a conventional linear methodology. This book starts from very basic linear algebra and reaches the cutting edge methodologies applied to difficult situations when there are many features (variables) while only small number of samples are available. The author includes advanced descriptions about tensor decomposition including Tucker decomposition using high order singular value decomposition as well as higher order orthogonal iteration, and train tenor decomposition. The author concludes by showing unsupervised methods and their application to a wide range of topics. Allows readers to analyze data sets with small samples and many features; Provides a fast algorithm, based upon linear algebra, to analyze big data; Includes several applications to multi-view data analyses, with a focus on bioinformatics.


Unsupervised Feature Extraction Applied to Bioinformatics

Unsupervised Feature Extraction Applied to Bioinformatics

Author: Y-h Taguchi

Publisher:

Published: 2020

Total Pages: 329

ISBN-13: 9783030224578

DOWNLOAD EBOOK

This book proposes applications of tensor decomposition to unsupervised feature extraction and feature selection. The author posits that although supervised methods including deep learning have become popular, unsupervised methods have their own advantages. He argues that this is the case because unsupervised methods are easy to learn since tensor decomposition is a conventional linear methodology. This book starts from very basic linear algebra and reaches the cutting edge methodologies applied to difficult situations when there are many features (variables) while only small number of samples are available. The author includes advanced descriptions about tensor decomposition including Tucker decomposition using high order singular value decomposition as well as higher order orthogonal iteration, and train tenor decomposition. The author concludes by showing unsupervised methods and their application to a wide range of topics. Allows readers to analyze data sets with small samples and many features; Provides a fast algorithm, based upon linear algebra, to analyze big data; Includes several applications to multi-view data analyses, with a focus on bioinformatics.


Application Of Omics, Ai And Blockchain In Bioinformatics Research

Application Of Omics, Ai And Blockchain In Bioinformatics Research

Author: Jeffrey J P Tsai

Publisher: World Scientific

Published: 2019-10-14

Total Pages: 207

ISBN-13: 9811203598

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With the increasing availability of omics data and mounting evidence of the usefulness of computational approaches to tackle multi-level data problems in bioinformatics and biomedical research in this post-genomics era, computational biology has been playing an increasingly important role in paving the way as basis for patient-centric healthcare.Two such areas are: (i) implementing AI algorithms supported by biomedical data would deliver significant benefits/improvements towards the goals of precision medicine (ii) blockchain technology will enable medical doctors to securely and privately build personal healthcare records, and identify the right therapeutic treatments and predict the progression of the diseases.A follow-up in the publication of our book Computation Methods with Applications in Bioinformatics Analysis (2017), topics in this volume include: clinical bioinformatics, omics-based data analysis, Artificial Intelligence (AI), blockchain, big data analytics, drug discovery, RNA-seq analysis, tensor decomposition and Boolean network.


Computational Methods With Applications In Bioinformatics Analysis

Computational Methods With Applications In Bioinformatics Analysis

Author: Jeffrey J P Tsai

Publisher: World Scientific

Published: 2017-06-09

Total Pages: 233

ISBN-13: 981320799X

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This compendium contains 10 chapters written by world renowned researchers with expertise in semantic computing, genome sequence analysis, biomolecular interaction, time-series microarray analysis, and machine learning algorithms.The salient feature of this book is that it highlights eight types of computational techniques to tackle different biomedical applications. These techniques include unsupervised learning algorithms, principal component analysis, fuzzy integral, graph-based ensemble clustering method, semantic analysis, interolog approach, molecular simulations and enzyme kinetics.The unique volume will be a useful reference material and an inspirational read for advanced undergraduate and graduate students, computer scientists, computational biologists, bioinformatics and biomedical professionals.


Computational Methods of Feature Selection

Computational Methods of Feature Selection

Author: Huan Liu

Publisher: CRC Press

Published: 2007-10-29

Total Pages: 437

ISBN-13: 1584888792

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Due to increasing demands for dimensionality reduction, research on feature selection has deeply and widely expanded into many fields, including computational statistics, pattern recognition, machine learning, data mining, and knowledge discovery. Highlighting current research issues, Computational Methods of Feature Selection introduces the


Data Analytics in Bioinformatics

Data Analytics in Bioinformatics

Author: Rabinarayan Satpathy

Publisher: John Wiley & Sons

Published: 2021-01-20

Total Pages: 433

ISBN-13: 111978560X

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Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel machine learning computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics approximating classification and prediction of disease, feature selection, dimensionality reduction, gene selection and classification of microarray data and many more.


Big Data Analytics in Bioinformatics and Healthcare

Big Data Analytics in Bioinformatics and Healthcare

Author: Wang, Baoying

Publisher: IGI Global

Published: 2014-10-31

Total Pages: 552

ISBN-13: 1466666129

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As technology evolves and electronic data becomes more complex, digital medical record management and analysis becomes a challenge. In order to discover patterns and make relevant predictions based on large data sets, researchers and medical professionals must find new methods to analyze and extract relevant health information. Big Data Analytics in Bioinformatics and Healthcare merges the fields of biology, technology, and medicine in order to present a comprehensive study on the emerging information processing applications necessary in the field of electronic medical record management. Complete with interdisciplinary research resources, this publication is an essential reference source for researchers, practitioners, and students interested in the fields of biological computation, database management, and health information technology, with a special focus on the methodologies and tools to manage massive and complex electronic information.


Handbook of Machine Learning Applications for Genomics

Handbook of Machine Learning Applications for Genomics

Author: Sanjiban Sekhar Roy

Publisher: Springer Nature

Published: 2022-06-23

Total Pages: 222

ISBN-13: 9811691584

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Currently, machine learning is playing a pivotal role in the progress of genomics. The applications of machine learning are helping all to understand the emerging trends and the future scope of genomics. This book provides comprehensive coverage of machine learning applications such as DNN, CNN, and RNN, for predicting the sequence of DNA and RNA binding proteins, expression of the gene, and splicing control. In addition, the book addresses the effect of multiomics data analysis of cancers using tensor decomposition, machine learning techniques for protein engineering, CNN applications on genomics, challenges of long noncoding RNAs in human disease diagnosis, and how machine learning can be used as a tool to shape the future of medicine. More importantly, it gives a comparative analysis and validates the outcomes of machine learning methods on genomic data to the functional laboratory tests or by formal clinical assessment. The topics of this book will cater interest to academicians, practitioners working in the field of functional genomics, and machine learning. Also, this book shall guide comprehensively the graduate, postgraduates, and Ph.D. scholars working in these fields.


Feature Extraction, Construction and Selection

Feature Extraction, Construction and Selection

Author: Huan Liu

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 418

ISBN-13: 1461557259

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There is broad interest in feature extraction, construction, and selection among practitioners from statistics, pattern recognition, and data mining to machine learning. Data preprocessing is an essential step in the knowledge discovery process for real-world applications. This book compiles contributions from many leading and active researchers in this growing field and paints a picture of the state-of-art techniques that can boost the capabilities of many existing data mining tools. The objective of this collection is to increase the awareness of the data mining community about the research of feature extraction, construction and selection, which are currently conducted mainly in isolation. This book is part of our endeavor to produce a contemporary overview of modern solutions, to create synergy among these seemingly different branches, and to pave the way for developing meta-systems and novel approaches. Even with today's advanced computer technologies, discovering knowledge from data can still be fiendishly hard due to the characteristics of the computer generated data. Feature extraction, construction and selection are a set of techniques that transform and simplify data so as to make data mining tasks easier. Feature construction and selection can be viewed as two sides of the representation problem.