Understanding Behavior in Huntington's Disease
Author: Jane S. Paulsen
Publisher:
Published: 1999-01-01
Total Pages: 46
ISBN-13: 9780963773043
DOWNLOAD EBOOKPosts
Learning to Live with Huntington's Disease
Author: Sandy Sulaiman
Publisher: Jessica Kingsley Publishers
Published: 2007
Total Pages: 178
ISBN-13: 1843104873
DOWNLOAD EBOOKHuntington's Disease (HD), is a hereditary illness passed on via a defective gene. This book offers one family's poignant story of coping with the symptoms, the diagnosis and the effects of HD. It also presents the struggles and strengths of the whole family when one member loses their future to a terminal illness.
Juvenile Onset Huntington's Disease
Author: Peggy C. Nopoulos
Publisher: MDPI
Published: 2021-01-14
Total Pages: 102
ISBN-13: 3039438115
DOWNLOAD EBOOKThe Special Issue “Juvenile Onset Huntington’s Disease” highlights the growing interest in understanding the unique aspects of this ultra-rare disorder. After decades of research, gene therapy trials are underway for Adult Onset Huntington’s Disease (AOHD). However, patients with Juvenile Onset Huntington’s Disease (JOHD) are often excluded from these efforts, leaving many questions regarding its phenomenology. The current issue includes seven articles spanning work on the difficult emotional experiences of parents of children with JOHD; a review of the clinical manifestations of JOHD; behavioral issues in JOHD; CAG repeat and age of motor onset; autonomic nervous system dysfunction; and abnormality in MRI metabolic markers. Finally, a review of the therapeutic advances is included, highlighting future possibilities of clinical trials in JOHD subjects. The HD community—patients, family members at-risk for HD, caregivers, health-care professionals and scientists—is keen on expanding our understanding of JOHD. In the flurry of research on AOHD, those with JOHD were seemingly ‘left behind.’ The study of patients who are afflicted early in life with HD has become imperative, with this Special Issue representing just the beginning of the required effort to address this urgent need.
A Physician's Guide to the Management of Huntington's Disease
Author: Adam Rosenblatt
Publisher:
Published: 1999-01-01
Total Pages: 85
ISBN-13: 9780963773029
DOWNLOAD EBOOKBehavioral Neurobiology of Huntington's Disease and Parkinson's Disease
Author: Hoa Huu Phuc Nguyen
Publisher: Springer
Published: 2015-05-23
Total Pages: 402
ISBN-13: 366246344X
DOWNLOAD EBOOKMotor dysfunction and cognitive impairment are major symptoms in both Huntington’s Disease (HD) and Parkinson’s Disease (PD). A breakthrough in HD research was the identification of the gene that causes this devastating monogenetic illness. Similarly, several genes were found to cause familial forms of PD. With their identification, a plethora of genetic animal models has been generated and has revolutionized the understanding of the pathobiology and pathophysiology of these disorders. The models allow us to study the earliest manifestations of the diseases behaviorally and neuropathologically and help us understand how they progress over time. Additionally, neurotoxic animal models are still of high interest to the PD field, as they are being used to study e.g. mitochondrial dysfunction in PD. This book focuses on animal models of both diseases and how they have helped and will continue to help understand the behavioral neurobiology in these disorders.
The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy
Author: Udo Rüb
Publisher: Springer
Published: 2015-09-29
Total Pages: 154
ISBN-13: 331919285X
DOWNLOAD EBOOKThis monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correlating neuropathological data with results on the functional neuroanatomy of the human brain, subsequent chapters will highlight recent HD findings: the neuronal loss in the cerebral neo-and allocortex, the neurodegeneration of select thalamic nuclei, the affection of the cerebellar cortex and nuclei, the involvement of select brainstem nuclei, as well as the pathophysiological relevance of these pathologies for the clinical picture of HD. Finally, the potential pathophysiological role of neuronal huntingtin aggregations and the most important and enduring challenges of neuropathological HD research are discussed.
Can You Help Me?
Author: Thomas D. Bird
Publisher:
Published: 2019
Total Pages: 289
ISBN-13: 0190684224
DOWNLOAD EBOOKCan You Help Me?: Living in the Turbulent World of Huntington Disease shares the surprising, insightful, challenging, and even encouraging stories of patients and their families who live with Huntington Disease. Having seen patients for more than 40 years, Dr Thomas Bird, a pioneer neurogeneticist, adds a human touch to this genetic brain disease that devastates persons during mid-life when they can least afford it. With a brief history of Huntington Disease and the occasional scientific detail, the true heart of the book is the human experience of the disorder: � The man who cannot stay out of prison because he is addicted to being a burglar. � Another man shoots and kills his roommate while watching television and cannot explain why he did it. � The woman with Huntington Disease copes with her depression by using Texas line dancing. � A twelve year old girl with juvenile Huntington Disease who can barely walk and talk, but her classmates rally around with touching and heartfelt support. � And the 72 year old man with late onset Huntington Disease and severe depression is made worse by ECT, but improved (for a while) with Transcranial Magnetic Stimulation. These are just some of the compelling stories of people of all ages and in all walks of life who feel trapped by a progressive degenerative brain disease from which there is no escape.
Understanding and Managing Behaviors of Children with Psychological Disorders
Author: Jered B. Kolbert
Publisher: Bloomsbury Publishing USA
Published: 2012-09-27
Total Pages: 632
ISBN-13: 1441165118
DOWNLOAD EBOOKIn the vast literature on classroom behavior management, there are no texts that offer a set of behavior management strategies specific to various psychopathology issues in children and adolescents. This book provides a clear, useful resource for educators who wish to either prevent or diminish problem behaviors exhibited in the classroom. Readers are presented with a brief description of various mental health diagnoses, including children on the autistic spectrum, with attention-deficit/ hyperactivity disorder, depression, anxiety, oppositional defiant disorder, and many others. After reviewing the features of each particular disorder, the book then offers a set of classroom management techniques designed to help educators target the associated problematic behaviors. Each chapter is written by an expert in that specific field, and strategies are provided for use with a variety of ages (from early childhood to adolescence). Educators will find this to be an essential tool for working with children and adolescents with a variety of mental health and behavioral disorders in the classroom.
Behavior Analysis and Learning
Author: Erin B. Rasmussen
Publisher: Taylor & Francis
Published: 2022-12-30
Total Pages: 691
ISBN-13: 1000817210
DOWNLOAD EBOOKUsing a behavioral perspective, Behavior Analysis and Learning provides an advanced introduction to the principles of behavior analysis and learned behaviors, covering a full range of principles from basic respondent and operant conditioning through applied behavior analysis into cultural design. The text uses Darwinian, neurophysiological, and biological theories and research to inform B. F. Skinner’s philosophy of radical behaviorism. The seventh edition expands the focus on neurophysiological mechanisms and their relation to the experimental analysis of behavior, providing updated studies and references to reflect current expansions and changes in the field of behavior analysis. By bringing together ideas from behavior analysis, neuroscience, epigenetics, and culture under a selectionist framework, the text facilitates understanding of behavior at environmental, genetic, neurophysiological, and sociocultural levels. This "grand synthesis" of behavior, neuroscience, and neurobiology roots behavior firmly in biology. The text includes special sections, "New Directions," "Focus On," "Note On," "On the Applied Side," and "Advanced Section," which enhance student learning and provide greater insight on specific topics. This edition was also updated for more inclusive language and representation of people and research across race, ethnicity, sexuality, gender identity, and neurodiversity. Behavior Analysis and Learning is a valuable resource for advanced undergraduate and graduate students in psychology or other behavior-based disciplines, especially behavioral neuroscience. The text is supported by Support Material that features a robust set of instructor and student resources: www.routledge.com/9781032065144.
Huntington's Disease
Author: Jurgen Lemiere
Publisher: Leuven University Press
Published: 2004
Total Pages: 164
ISBN-13: 9789058674227
DOWNLOAD EBOOKThis is a Ph.D. dissertation. Huntington's Disease (HD) is a dominantly inherited late onset neurodegenerative disorder, initially affecting the basal ganglia and especially the head of the caudate nucleus. Eventually, atrophy is more diffuse extending to the cerebral cortex and other brain nuclei. A triad of progressive motor, cognitive, and emotional symptoms characterizes adult onset HD. Contents include: General Introduction and Aims of the Study, Cognitive Changes in Patients with HD and Asymptomatic Carriers of the HD Mutation, Recent Memory and Recognition Memory in Huntington's Disease, Habitual Learning in Huntington's and Parkinson's Disease, Effect of Oral Creatine Supplementation on Cognition in HD, General Summary and Perspectives.
