Ultrastructural Pathology of the Cell and Matrix

Ultrastructural Pathology of the Cell and Matrix

Author: Feroze N. Ghadially

Publisher: Butterworth-Heinemann

Published: 2013-10-22

Total Pages: 778

ISBN-13: 1483192091

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Ultrastructural Pathology of the Cell and Matrix: Third Edition Volume 2 presents a comprehensive examination of the intracellular lesion. It discusses the analysis of pathological tissues using electron microscope. It addresses the experimental procedures made on the cellular level. Some of the topics covered in the book are the structure, distribution, and variations of rod-shaped microtubulated bodies; morphology of intracytoplasmic filaments; melanosome-producing and melanosome-containing cells in tumours; myofilaments in striated muscle; and pathological variations in size, shape, and numbers of microbodies. The intracytoplasmic and intranuclear annulate lamellae are fully covered. An in-depth account of the classification, history, and nomenclature of lysosomes are provided. The morphology and normal variations of melanosomes and anchoring fibrils are completely presented. A chapter is devoted to the endocytotic structures and cell processes. Another section focuses on the classification and nomenclature of fibrous components. The book can provide useful information to cytologists, pathologists, students, and researchers.


Ultrastructural Pathology of the Cell and Matrix

Ultrastructural Pathology of the Cell and Matrix

Author: Feroze N. Ghadially

Publisher: Butterworth-Heinemann

Published: 2013-10-22

Total Pages: 612

ISBN-13: 1483192083

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Ultrastructural Pathology of the Cell and Matrix: Third Edition Volume I present a comprehensive examination of the intracellular lesion. It discusses the analysis of pathological tissues using electron microscope. It addresses the experimental procedures made on the cellular level. Some of the topics covered in the book are the physiological analysis of the nucleus; nuclear matrix, interchromatin, and perichromatin granules; structure and function of centrioles; characteristics of mitochondria; Golgi complex in cell differentiation and neoplasia; and degranulation of rough endoplasmic reticulum. The intracytoplasmic and intranuclear annulate lamellae are fully covered. An in-depth account of the classification, history, and nomenclature of lysosomes are provided. The morphology and normal variations of melanosomes and anchoring fibrils are completely presented. A chapter is devoted to the endocytotic structures and cell processes. Another section focuses on the classification and nomenclature of fibrous components. The book can provide useful information to cytologists, scientists, students, and researchers.


Ultrastructural Pathology of the Cell and Matrix, 4Ed

Ultrastructural Pathology of the Cell and Matrix, 4Ed

Author: Feroze Ghadially

Publisher: CRC Press

Published: 1997-01-24

Total Pages: 1424

ISBN-13: 9780750696357

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Ghadially successfully collects, classifies, describes, and illustrates the ultrastructure of every normal and pathological intracellular and extracellular structure in humans and other animals. This authoritative work serves as a textbook and atlas of cellular pathology at the ultrastructural level. There is no other book from which one may learn in a systemic fashion about the numerous changes that occur in cellular organelles and inclusions as a result of disease or experimental procedures. The 4th edition includes a number of new ultrastructural changes and lesions such as, secretory granules in bronchio-alveolar carcinoma, fibrohistiocytes, crinophagy in normal and neoplastic cells, and interdigitations and infoldings of the cell membrane.


Ultrastructure of the Kidney

Ultrastructure of the Kidney

Author: Albert J. Dalton

Publisher: Academic Press

Published: 2013-09-17

Total Pages: 253

ISBN-13: 1483266478

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Ultrastructure in Biological Systems, Volume 2: Ultrastructure of the Kidney provides an overview of the state of knowledge on the ultrastructure of the mammalian kidney. The application of the electron microscope to studies of the kidney resulted in the demonstration of the hitherto undetected early thickening of the basement membrane of glomerular capillaries in glomerulonephritis. Yet many problems remain, particularly in relation to the correlation between function and the ultrastructure of components of the kidney—mesangium, glomerulus, juxtaglomerular apparatus, and the renal tubules. It is only recently that the mesangium has come to be accepted as real, and many questions remain as to the function of its cells. The existence of true membranes between foot processes of the epithelial cells of glomeruli is a newly established fact; but what this has to do with glomerular filtration is not known at present. Granules apparently secretory in nature have been identified in cells of the juxtaglomerular apparatus, but so far their presence has not been correlated with specific functional change. Artifacts introduced at fixation are now known to have considerable relevance in interpreting the ultrastructure of the normal nephron. These are paraphrased views of the contributors to this monograph who, while acquainting the reader with the research being carried on in these areas, have also brought into focus the many problems still awaiting solution.


Ultrastructure of the Connective Tissue Matrix

Ultrastructure of the Connective Tissue Matrix

Author: P. Motta

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 224

ISBN-13: 1461328314

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In recent years, the techniques of electron microscopy have developed so widely and rapidly that they now cover the fields of research once the unique ll:panage of sister research techniques such as biochemistry, physiology, immunology, X-ray diffraction, etc. It is now possible to reach molecular and submolecular levels, making this technique indispensable in every type of research. Electron microscopy alone often provides enough information to solve given problems. In the field of the connective tissue matrix, knowledge of the molecular structure of collagen, pro teoglycans and elastin and their interaction has been to a large extent elucidated by electron microscopy. The field over which electron microscopy ranges in the investigation of the connective tissue matrix is so wide that the aim of this volume is to collect the main ultrastructural acquisitions disseminated in various journals and monographs in one book. The intent ofthis volume is to: (a) integrate different and new microscopic methods and review the results of such an integrative approach; (b) present a comprehensive ultrastructural account of selected aspects of the field; (c) point out gaps or controversial topics in our knowledge; (d) outline pertinent future research and expansion of the subject.


Information Resources in Toxicology

Information Resources in Toxicology

Author: P.J. Bert Hakkinen

Publisher: Academic Press

Published: 2009-08-19

Total Pages: 1553

ISBN-13: 0080920039

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This latest version of Information Resources in Toxicology (IRT) continues a tradition established in 1982 with the publication of the first edition in presenting an extensive itemization, review, and commentary on the information infrastructure of the field. This book is a unique wide-ranging, international, annotated bibliography and compendium of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. Thoroughly updated, the current edition analyzes technological changes and is rife with online tools and links to Web sites. IRT-IV is highly structured, providing easy access to its information. Among the "hot topics covered are Disaster Preparedness and Management, Nanotechnology, Omics, the Precautionary Principle, Risk Assessment, and Biological, Chemical and Radioactive Terrorism and Warfare are among the designated. - International in scope, with contributions from over 30 countries - Numerous key references and relevant Web links - Concise narratives about toxicologic sub-disciplines - Valuable appendices such as the IUPAC Glossary of Terms in Toxicology - Authored by experts in their respective sub-disciplines within toxicology