Neuroinflammation and Cognition
Neuroinflammation and Cognition

Author: Ashok Kumar

Publisher: Frontiers Media SA

Published: 2019-03-22

Total Pages: 191

ISBN-13: 2889457605

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Aging is one of the major risk factors for the onset and progression of various neurodegenerative diseases. Neuroinflammation is a common feature of virtually every central nervous system disease, and is acknowledged as a likely mediator of cognitive impairments. Systemic inflammation levels are augmented with advanced age and neurodegeneration. The influence of age on neuroinflammatory responses including glial activation, increased production of proinflammatory cytokines, and aberrant neuronal signaling could magnify the deterioration of the central nervous system microenvironment in disease, and may contribute to enhanced cognitive impairment. This eBook is a collection of highly informative original research articles, providing comprehensive aspect of neuroinflammation and possible therapeutic interventions in rescuing cognitive impairments.

Schizo-Obsessive Disorder
Schizo-Obsessive Disorder

Author: Michael Poyurovsky

Publisher: Cambridge University Press

Published: 2013-01-17

Total Pages: 249

ISBN-13: 1107000122

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This is the first book to address the clinical and neurobiological interface between schizophrenia and obsessive-compulsive disorder (OCD). There is growing evidence that obsessive-compulsive symptoms in schizophrenia are prevalent, persistent and characterized by a distinct pattern of familial inheritance, neurocognitive deficits and brain activation. This text provides guidelines for differential diagnosis of schizophrenic patients with obsessive-compulsive symptoms, and patients with primary OCD alongside poor insight, psychotic features or schizotypal personality. Written by a leading expert in the coexistence of obsessive-compulsive and schizophrenic phenomena, Schizo-Obsessive Disorder uses numerous case studies to present diagnostic guidelines and to describe a recommended treatment algorithm, demystifying this complex disorder and aiding its effective management. The book is essential reading for psychiatrists, neurologists and the wider range of multidisciplinary mental health practitioners.

Women & Psychosis
Women & Psychosis

Author: Marie Brown

Publisher: Rowman & Littlefield

Published: 2019-03-13

Total Pages: 227

ISBN-13: 1498591922

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Interrogating the relationship between women and psychosis from a variety of perspectives, this edited collection explores personal, literary, spiritual, psychological, biological, and psychodynamic approaches. The contributors reflect on medieval mystics and witches, postpartum psychosis, disordered eating, art and literature, feminism, and male/female differences in schizophrenia. Women with experience of psychosis, psychotherapists, and a shaman provide first-person accounts to give the book a personal grounding. Curated with the intent to expand the way we think about women and psychosis, the contributors to this collection recognize that “voices and visions” do not occur in a vacuum, but are experienced within, and are influenced by, particular socio-cultural contexts.

Reducing Risks for Mental Disorders
Reducing Risks for Mental Disorders

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1994-01-01

Total Pages: 636

ISBN-13: 0309049393

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The understanding of how to reduce risk factors for mental disorders has expanded remarkably as a result of recent scientific advances. This study, mandated by Congress, reviews those advances in the context of current research and provides a targeted definition of prevention and a conceptual framework that emphasizes risk reduction. Highlighting opportunities for and barriers to interventions, the book draws on successful models for the prevention of cardiovascular disease, injuries, and smoking. In addition, it reviews the risk factors associated with Alzheimer's disease, schizophrenia, alcohol abuse and dependence, depressive disorders, and conduct disorders and evaluates current illustrative prevention programs. The models and examination provide a framework for the design, application, and evaluation of interventions intended to prevent mental disorders and the transfer of knowledge about prevention from research to clinical practice. The book presents a focused research agenda, with recommendations on how to develop effective intervention programs, create a cadre of prevention researchers, and improve coordination among federal agencies.

Novel Antischizophrenia Treatments
Novel Antischizophrenia Treatments

Author: Mark A. Geyer

Publisher: Springer Science & Business Media

Published: 2012-10-01

Total Pages: 456

ISBN-13: 3642257585

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This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume concentrates on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.

Schizophrenia Treatment Outcomes
Schizophrenia Treatment Outcomes

Author: Amresh Shrivastava

Publisher: Springer Nature

Published: 2020-02-05

Total Pages: 351

ISBN-13: 3030198472

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This book analyzes schizophrenia management in the context of recent clinical therapeutic advances that have transformed the measurements and outcomes landscape. Unlike any other resource, this volume carefully develops the social and clinical guidelines that affect the life of the patient and defines its role in schizophrenia treatment outcomes. The text begins by determining the concepts, development, neuroscience, and guidelines for positive outcomes before analyzing the gaps in the literature. The text addresses medical concerns in relation to outcomes in schizophrenic patients, including substance use, impact from antipsychotic medications, and medical comorbidities. The text also covers external determinants that may inhibit positive outcomes, including cultural factors, stigma, and environmental issues. Written by experts in schizophrenia care, this book compiles sound research, current clinical trends, and modern measurement markers into a well-organized compendium that delivers this data into a practical guide for measuring treatment outcomes in patients suffering from the disease. Schizophrenia Treatment Outcomes is the ultimate guide for psychiatrists, psychologists, nurses, social workers, and all medical practitioners interested in improving outcomes for schizophrenia patients.

The Neurobiology of Schizophrenia
The Neurobiology of Schizophrenia

Author: Ted Abel

Publisher: Academic Press

Published: 2016-07-08

Total Pages: 470

ISBN-13: 0128018771

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The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. Provides a comprehensive overview of neurobiological aspects of schizophrenia Discusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance Elucidates connections between the various systems depicted, when possible