Arboviruses
Arboviruses

Author: Nikos Vasilakis

Publisher: Caister Academic Press Limited

Published: 2016

Total Pages: 0

ISBN-13: 9781910190210

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Arthropod-borne viruses (arboviruses) are the causative agents of significant morbidity and mortality among humans and domestic animals globally. They are maintained in complex biological life cycles, involving a primary vertebrate host and a primary arthropod vector. While all known arboviruses are zoonotic pathogens, their emergence as human pathogens is associated with dramatic increases of human population growth leading to uncontrolled urbanization, changes in land and water use, changes in agricultural practices, new irrigation systems and deforestation. This book brings together a panel of expert arbovirologists to produce a timely review of the rapidly expanding arbovirus research literature. In addition authors identify the most pressing questions that remain to be answered, thus providing a stimulus for future research. Topics include: taxonomy, genome organization, virus-host and virus-vector interactions, evolutionary history, role of vertical transmission in arbovirus maintenance and evolution, epidemiology, arbovirus replication, pathogenesis, arbovirus diagnostics and control, including vaccines, novel anti-viral drugs, RNA interference and genetically modified vectors. Essential reading for every arbovirologist and highly recommended for all virologists and public health officials. [Subject: Microbiology, Life Science, Arbovirology, Virology, Taxonomy, Epidemiology]

The New Public Health
The New Public Health

Author: Theodore H. Tulchinsky

Publisher: Academic Press

Published: 2014-03-26

Total Pages: 911

ISBN-13: 012415767X

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The New Public Health has established itself as a solid textbook throughout the world. Translated into 7 languages, this work distinguishes itself from other public health textbooks, which are either highly locally oriented or, if international, lack the specificity of local issues relevant to students' understanding of applied public health in their own setting. This 3e provides a unified approach to public health appropriate for all masters' level students and practitioners—specifically for courses in MPH programs, community health and preventive medicine programs, community health education programs, and community health nursing programs, as well as programs for other medical professionals such as pharmacy, physiotherapy, and other public health courses. - Changes in infectious and chronic disease epidemiology including vaccines, health promotion, human resources for health and health technology - Lessons from H1N1, pandemic threats, disease eradication, nutritional health - Trends of health systems and reforms and consequences of current economic crisis for health - Public health law, ethics, scientific d health technology advances and assessment - Global Health environment, Millennium Development Goals and international NGOs

Rapid Virus Diagnosis
Rapid Virus Diagnosis

Author: P. S. Gardner

Publisher: Butterworth-Heinemann

Published: 2014-06-28

Total Pages: 336

ISBN-13: 1483192172

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Rapid Virus Diagnosis: Application of Immunofluorescence presents developments in immunofluorescence as a technique for the diagnosis of virus infections. It discusses the effective and rapid methods for the diagnosis of virus infections. It addresses the application of fluorescent antibody techniques to the diagnosis and the investigation of virus infections and the assessment of their value both to the clinician and to the virologist. Some of the topics covered in the book are the fluorescence microscopy; nature of fluorescence; filter systems; transmitted light microscopy; interference filters for transmitted light microscopy; lamp centration and alignment of microscope; contrast-fluorescence condensers; photomicrography; and choice of microscope. The culture of viruses for production of antiserum is fully covered. The selection of cell lines or tissues for virus culture is discussed in detail. The text describes in depth the fluorescent antibody staining techniques. The preparation of specimens from respiratory infections is presented completely. A chapter is devoted to the respiratory syncytial virus. Another section focuses on the analysis influenza virus, paramyxoviruses, and picornaviruses. The book can provide useful information to doctors, virologists, students, and researchers.

New Drug Development for Known and Emerging Viruses
New Drug Development for Known and Emerging Viruses

Author: Helga Rübsamen-Schaeff

Publisher: John Wiley & Sons

Published: 2021-11-30

Total Pages: 530

ISBN-13: 3527810706

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Discusses how to fight Ebola, SARS Corona, and other known or emerging human viruses by building on the successes in antiviral therapy of the past decades Written by leading medicinal chemists from academia and industry, this book discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets, and viral disease mechanisms. It provides an outlook on emerging pathogens such as Ebola, Zika, West Nile, Lassa, and includes a chapter on SARS Coronoavirus-2 causing the present pandemic. New Drug Development for Known and Emerging Viruses describes the discovery and development process for antiviral agents for different classes of viruses and targets based on the experiences from the nine human viruses for which approved drugs are on the market (HIV, HCV, Influenza, RSV, HBV, HPV, HCMV, HSV, and VZV). It covers the properties and potential of 20 classes of currently approved antivirals, including combination drugs, and looks at novel antiviral strategies against emerging viruses. Covers the entire field of antiviral drug discovery and development Addresses the need for antiviral drugs to combat major health threats such as Ebola, Zika, West Nile, and SARS Coronavirus-2 Summarizes the successes of the past 15 years in developing ground-breaking medicines against 9 major human viruses, both from the medicinal chemistry and the pharmacological angle Discusses practical and strategic challenges in the drug discovery and development process, including screening technologies, latency, and toxicity issues New Developments in Antiviral Drugs is an important book for medicinal chemists, pharmaceutical chemists, virologists, and epidemiologists, and will be of great interest to those in the ;pharmaceutical industry and public health agencies.

Arthropod Borne Diseases
Arthropod Borne Diseases

Author: Carlos Brisola Marcondes

Publisher: Springer

Published: 2016-11-09

Total Pages: 642

ISBN-13: 3319138847

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Arthropod borne diseases cause enormous morbidity and mortality in most countries, mostly in those situated in tropical areas, but also in temperate regions. This book provides organized information on all arthropod related diseases, to prevent suffering and deaths, for medical students and professionals. Since arthropod borne diseases are present in many regions of the world and can even surprise professionals and lays in non-endemic regions, like malaria in UK and Canada, the author and its many expert collaborators are sure that it will be essential in all hospitals, clinics and medical libraries around the world. As arthropod borne diseases of domesticated animals are very numerous and in some cases related to human diseases, they are also included in the book.

Infectious Diseases from Nature: Mechanisms of Viral Emergence and Persistence
Infectious Diseases from Nature: Mechanisms of Viral Emergence and Persistence

Author: C.J. Peters

Publisher: Springer

Published: 2005-09-27

Total Pages: 216

ISBN-13: 9783211243350

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Significant zoonotic diseases have appeared with increasing frequency in recent years. At a symposium held in Galveston, Texas, in March 2004, many outstanding virologists and others presented papers under the broad theme of "emergence". The intent was to elucidate the diseases themselves, the mechanisms by which they have emerged, the publication perception and response to the diseases, and the possibility of prevention or prediction. The papers in this book summarize the talks of this meeting. Among the many timely papers are those by Nobel Prize winner Peter Doherty, influenza epidemiologists Robert Webster and Jeffery Taubenberger, and important contributions by Neal Nathanson, Esteban Domingo, Barry Beaty, David Walker, James Hughes, and others of world expertise.

Dengue and Zika: Control and Antiviral Treatment Strategies
Dengue and Zika: Control and Antiviral Treatment Strategies

Author: Rolf Hilgenfeld

Publisher: Springer

Published: 2018-05-29

Total Pages: 375

ISBN-13: 981108727X

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This contributed volume contains 25 chapters from leading international scientists working on dengue and Zika viruses, who came together in Praia do Tofo in Mozambique to discuss the latest developments in the fields of epidemiology, pathogenesis, structural virology, immunology, antiviral drug discovery and development, vaccine efficacy, and mosquito control programs. The meeting venue offered an opportunity to discuss current research on these flaviviruses in an idyllic setting, and also to develop first-hand appreciation of the issues in infectious diseases facing developing countries and of the research gaps in Africa. For readers, who should include basic and clinical researchers in the field and public health professionals, the chapters are organized to provide a comprehensive overview of the various topics in current dengue and Zika virus research. A unique feature of the proceedings of this meeting is the inclusion of the discussions that took place following presentations. These have been transcribed and appended to the end of the relevant chapters, and they form the “salt in the soup” of this book.

Microbe-vector Interactions in Vector-borne Diseases
Microbe-vector Interactions in Vector-borne Diseases

Author: S. H. Gillespie

Publisher: Cambridge University Press

Published: 2004-05-06

Total Pages: 410

ISBN-13: 9781139442916

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Several billion people are at daily risk of life threatening vector-borne diseases such as malaria, trypanosomiasis and dengue. This volume describes the way in which the causal pathogens of such diseases interact with the vectors that transmit them. It details the elegant biological adaptations that have enabled pathogens to live with their vectors and, in some circumstances, to control them. This knowledge has led to novel preventative strategies in the form of antibiotics and new vaccines which are targeted not at the pathogen itself but at its specific vector.

Transmission and Infection of Arboviruses
Transmission and Infection of Arboviruses

Author: Ke Liu

Publisher: Frontiers Media SA

Published: 2024-04-17

Total Pages: 162

ISBN-13: 2832548008

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Worldwide, the most important arboviruses are chikungunya, dengue, Japanese encephalitis, Mayaro, West Nile, Zika, and Ross River viruses. A significant public health threat is posed by these viruses around the world, which threaten more than 3.6 billion people. In recent decades, scientists have revealed many issues with arboviruses and established approaches, allowing us to fight the diseases more effectively. However, old and new problems continue to haunt us, motivating us to develop new approaches to fight these diseases. A growing number of arboviruses have been detected in different regions of the world, emphasizing the need to better understand how these viruses are transmitted and infect.