Transgenesis and the Management of Vector-Borne Disease

Transgenesis and the Management of Vector-Borne Disease

Author: Serap Aksoy

Publisher: Springer Science & Business Media

Published: 2008-08-21

Total Pages: 187

ISBN-13: 0387782257

DOWNLOAD EBOOK

Parasitic, bacterial and viral agents continue to challenge the welfare of humans, livestock, wild life and plants worldwide. The public health impact and financial consequences of these diseases are particularly hard on the already overburdened economies of developing countries especially in the tropics. Many of these disease agents utilize insect hosts (vectors) to achieve their transmission to mammals. In the past, these diseases were largely controlled by insecticide-based vector reduction strategies. Now, many of these diseases have reemerged in the tropics, recolonizing their previous range, and expanding into new territories previously not considered to be endemic. Habitat change, irrigation practices, atmospheric and climate change, insecticide and drug resistance as well as increases in global tourism, human traffic and commercial activities, have driven the reemergence and spread of vector borne diseases. While these diseases can be controlled through interventions aimed at both their vertebrate and invertebrate hosts, no effective vaccines exist, and only limited therapeutic prospects are available for their control in mammalian hosts. Molecular technologies such as transgenesis, which is the subject of this book, stand to increase the toolbox and benefit disease management strategies.


Biodiversity and Health in the Face of Climate Change

Biodiversity and Health in the Face of Climate Change

Author: Melissa R. Marselle

Publisher: Springer

Published: 2019-06-11

Total Pages: 494

ISBN-13: 3030023184

DOWNLOAD EBOOK

This open access book identifies and discusses biodiversity’s contribution to physical, mental and spiritual health and wellbeing. Furthermore, the book identifies the implications of this relationship for nature conservation, public health, landscape architecture and urban planning – and considers the opportunities of nature-based solutions for climate change adaptation. This transdisciplinary book will attract a wide audience interested in biodiversity, ecology, resource management, public health, psychology, urban planning, and landscape architecture. The emphasis is on multiple human health benefits from biodiversity - in particular with respect to the increasing challenge of climate change. This makes the book unique to other books that focus either on biodiversity and physical health or natural environments and mental wellbeing. The book is written as a definitive ‘go-to’ book for those who are new to the field of biodiversity and health.


Genetically Modified Mosquitoes for Malaria Control

Genetically Modified Mosquitoes for Malaria Control

Author: Christophe Boete

Publisher: CRC Press

Published: 2006-07-15

Total Pages: 198

ISBN-13:

DOWNLOAD EBOOK

This book describes the epidemiological and evolutionary consequences of the use of genetically modified (GM) mosquitoes as well as research orientations and ethical issues concerning the use of GM mosquitoes. It also includes discussion on transgenic mosquitoes for malaria control.


Gene Drives on the Horizon

Gene Drives on the Horizon

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2016-08-28

Total Pages: 231

ISBN-13: 0309437873

DOWNLOAD EBOOK

Research on gene drive systems is rapidly advancing. Many proposed applications of gene drive research aim to solve environmental and public health challenges, including the reduction of poverty and the burden of vector-borne diseases, such as malaria and dengue, which disproportionately impact low and middle income countries. However, due to their intrinsic qualities of rapid spread and irreversibility, gene drive systems raise many questions with respect to their safety relative to public and environmental health. Because gene drive systems are designed to alter the environments we share in ways that will be hard to anticipate and impossible to completely roll back, questions about the ethics surrounding use of this research are complex and will require very careful exploration. Gene Drives on the Horizon outlines the state of knowledge relative to the science, ethics, public engagement, and risk assessment as they pertain to research directions of gene drive systems and governance of the research process. This report offers principles for responsible practices of gene drive research and related applications for use by investigators, their institutions, the research funders, and regulators.


Animal Biotechnology

Animal Biotechnology

Author: National Research Council

Publisher: National Academies Press

Published: 2002-11-29

Total Pages: 200

ISBN-13: 030916933X

DOWNLOAD EBOOK

Genetic-based animal biotechnology has produced new food and pharmaceutical products and promises many more advances to benefit humankind. These exciting prospects are accompanied by considerable unease, however, about matters such as safety and ethics. This book identifies science-based and policy-related concerns about animal biotechnologyâ€"key issues that must be resolved before the new breakthroughs can reach their potential. The book includes a short history of the field and provides understandable definitions of terms like cloning. Looking at technologies on the near horizon, the authors discuss what we know and what we fear about their effectsâ€"the inadvertent release of dangerous microorganisms, the safety of products derived from biotechnology, the impact of genetically engineered animals on their environment. In addition to these concerns, the book explores animal welfare concerns, and our societal and institutional capacity to manage and regulate the technology and its products. This accessible volume will be important to everyone interested in the implications of the use of animal biotechnology.


Demography and Vector-Borne Diseases

Demography and Vector-Borne Diseases

Author: Michael W. Service

Publisher: CRC Press

Published: 2024-11-01

Total Pages: 422

ISBN-13: 1040278280

DOWNLOAD EBOOK

An in-depth overview on the demo-graphic changes occurring world-wide and the repercussions this is having on the pattern of vector-borne disease is pre-sented in this book. Internationally recognized scientists, epidemiologists, entomologists, parasitologists, and ecologists are contributing authors to this comprehensive account.


Vector Biology, Ecology and Control

Vector Biology, Ecology and Control

Author: Peter W. Atkinson

Publisher: Springer Science & Business Media

Published: 2009-12-12

Total Pages: 258

ISBN-13: 9048124581

DOWNLOAD EBOOK

Mir S. Mulla joined the faculty of the Entomology Department at the University of California, Riverside in 1956, only two years after the Riverside campus was established as an independent campus within the University of California system. Prior to his appointment, Mir received his B.S. from Cornell University and then moved to the University of California, Berkeley to pursue his graduate studies. His Ph.D. from Berkeley, awarded in 1955, completed his formal American education which was the purpose of his immigration from his native Kandahar in Afghanistan. In his over 50 years at Riverside, Mir has made an incalculable impact on vector biology both within the United States and in developing countries throughout the world. Within Southern California, Mir’s basic and applied research led to the rapid and sustainable control of mosquitoes and eye gnats in the Coachella Valley and so directly enabled this region to grow to the thriving, large community it is today. In 2006 his efforts in facilitating the development of the low desert of southern California were recognized through the dedication of the Mir S. Mulla Biological Control Facility by the Coachella Valley Mosquito and Vector Control District. His success has been so profound that it remains somewhat cryptic to the many who now reside in, visit, and enjoy, this region of California, oblivious to the insect problems that severely restrained development until Mir and his students ?rst applied their expertise many decades ago.


Genetic Control of Malaria and Dengue

Genetic Control of Malaria and Dengue

Author: Zach N. Adelman

Publisher: Academic Press

Published: 2015-10-15

Total Pages: 487

ISBN-13: 0128004053

DOWNLOAD EBOOK

Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown. - Includes coverage of vectorial capacity, critical to understanding vector-borne disease transmission - Provides a summary of the concepts of both population suppression and population replacement - Contains pivotal coverage of ethical and ecological ramifications of genetics-based control strategies


Environmental Effects of Transgenic Plants

Environmental Effects of Transgenic Plants

Author: National Research Council

Publisher: National Academies Press

Published: 2002-02-22

Total Pages: 342

ISBN-13: 0309170176

DOWNLOAD EBOOK

Transgenic crops offer the promise of increased agricultural productivity and better quality foods. But they also raise the specter of harmful environmental effects. In this new book, a panel of experts examines: • Similarities and differences between crops developed by conventional and transgenic methods • Potential for commercialized transgenic crops to change both agricultural and nonagricultural landscapes • How well the U.S. government is regulating transgenic crops to avoid any negative effects. Environmental Effects of Transgenic Plants provides a wealth of information about transgenic processes, previous experience with the introduction of novel crops, principles of risk assessment and management, the science behind current regulatory schemes, issues in monitoring transgenic products already on the market, and more. The book discusses public involvementâ€"and public confidenceâ€"in biotechnology regulation. And it looks to the future, exploring the potential of genetic engineering and the prospects for environmental effects.


Pests and Vector-borne Diseases in the Livestock Industry

Pests and Vector-borne Diseases in the Livestock Industry

Author: Claire Garros

Publisher: Brill Wageningen Academic

Published: 2018

Total Pages: 0

ISBN-13: 9789086863150

DOWNLOAD EBOOK

"How to control economically important vector-borne diseases? What are the best strategies to protect livestock from vector-borne diseases in a changing environment? How to evaluate and assess the acceptability, cost efficiency and cost benefit of the control and surveillance methods? The information in this book will help to answer these questions. It aims at presenting the latest information on vector-borne diseases affecting livestock worldwide, from state-of-the art interventions to the assessment of the impact of these control measures. This book is a valuable tool for entomologists and all those involved in pest and vector control."