Toxicology and Carcinogenesis Studies of Anthraquinone in F344/N Rats and B6C3F, Mice
Toxicology and Carcinogenesis Studies of Anthraquinone in F344/N Rats and B6C3F, Mice

Author: R. D. Irwin

Publisher:

Published: 2006-04

Total Pages: 358

ISBN-13: 9781422303498

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Anthraquinone is used as an intermediate in the manufacture of dyes & pigments, an additive in the kraft pulping process in the paper industry, a catalyst in the isomerization of vegetable oils, an accelerator in nickel electroplating, & as a bird repellent. The Nat. Toxicology Program (NTP) studied anthraquinone to determine if it caused cancer in rats or mice. They conclude that anthraquinone caused cancer of the kidney & urinary bladder in male & female rats & of the liver in female rates. The occurrence of some liver tumors in male rats may have been related to anthraquinone exposure. The NTP concludes that anthraquinone caused liver cancer in male & female mice, & thyroid gland tumors in mice may have been related to anthraquinone. Illus.

Report on Carcinogens (12th Ed. )
Report on Carcinogens (12th Ed. )

Author: Nat. Toxicology Program (NTP) (NIH)

Publisher: DIANE Publishing

Published: 2011-10-08

Total Pages: 507

ISBN-13: 1437987362

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The Report on Carcinogens (RoC) is a congressionally mandated, science-based, public health document that identifies and discusses agents, substances, mixtures, or exposure circumstances (hereinafter referred to as "substances") that may pose a hazard to human health by virtue of their carcinogenicity. For each listed substance, the report contains a substance profile which provides information on (1) the listing status, (2) cancer studies in humans and animals, (3) studies of genotoxicity (ability to damage genes) and biologic mechanisms, (4) the potential for human exposure to these substances, and (5) Federalregulations to limit exposures. Eight substances have been added to this 12th ed. of the report, which now includes 240 listings. The industrial chemical formaldehyde and a botanical known as aristolochic acids are listed as known human carcinogens. Six other substances captafol, cobalt-tungsten carbide (in powder or hard metal form), certain inhalable glass wool fibers, o-nitrotoluene, riddelliine, and styrene are added as substances that are reasonably anticipated to be human carcinogens. Figures. This is a print on demand report.

Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water
Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water

Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Publisher: IARC Monographs on the Evaluat

Published: 2013

Total Pages: 0

ISBN-13: 9789283213246

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This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.