Head and Neck Cancer

Head and Neck Cancer

Author: Jacques Bernier

Publisher: Springer Science & Business Media

Published: 2011-06-15

Total Pages: 700

ISBN-13: 1441994645

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In recent years, great advances in translational research have led to new paradigms in the treatment of cancers of the head and neck. Written by leading international physicians and investigators, this innovative multi-disciplinary book presents the most up-to-date research and clinical approaches. Coverage is given to progress in a variety of clinical settings, including programs of organ and function preservation, curative treatments, unresectable disease, adjuvant treatments in high-risk patients, and recurrent/metastatic disease. Complementary to the techniques of surgery, radiotherapy, and systemic treatments, the authors present data on epidemiology, molecular pathology, normal tissue complications, rehabilitation, palliative care, and treatment in the elderly. State-of-the-art functional imaging is elucidated; and the latest developments in high precision techniques in irradiation, sequencing of chemo- and radiotherapy, as well as the integration of biomolecular therapies into cytotoxic treatments are explored.


Function Preservation in Laryngeal Cancer, An Issue of Otolaryngologic Clinics of North America

Function Preservation in Laryngeal Cancer, An Issue of Otolaryngologic Clinics of North America

Author: Babak Sadoughi

Publisher: Elsevier Health Sciences

Published: 2015-11-12

Total Pages: 217

ISBN-13: 0323389015

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Cancers of the larynx, while survival outcomes increase, result in massive treatment damage from radiation and surgery. Patients often lose ability to speak and to eat. Preserving the larynx is a fine balance of cancer eradication, life extension, and quality of life. This issueof Otolaryngologic Clinics led by Dr Babak Sadoughi should be of interest to Otolaryngologists, Oncologists, Radiologists, and Speech Therapists. The issue approach reaches all the most important aspects of diagnosing and treating the patient with laryngeal cancer with a focus on preserving the voice in early laryngeal cancer and preserving and restoring function in advanced laryngeal cancer. Topics include: Functional Anatomy and Oncological Barriers of the Larynx; Evaluation of the Dysphonic Patient; Role of Advanced Laryngeal Imaging in Glottic Cancer; Laryngeal Function after Radiation Therapy; Management of Dysphonia after Radiation Therapy; Contemporary Surgical Management of Early Glottic Cancer; Voice Prognosis after Transoral Laser Microsurgery of the Larynx; Voice Rehabilitation after Transoral Laser Microsurgery of the Larynx; Quality of Life after Conservation Surgery for Laryngeal Cancer; Salvage Conservation Surgery of the Larynx; Airway Preservation in Ablative Laryngeal Surgery; Voice Restoration after Total Laryngectomy. A special article for Residents, written by a Resident, emphasizes essential "take home messages" for laryngeal function preservation diagnosis and treatment.


Carcinomas of the Head and Neck

Carcinomas of the Head and Neck

Author: Charlotte Jacobs

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 290

ISBN-13: 1461314992

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It was not too many years ago that the role of chemotherapy for head and neck cancer consisted of single-agent methotrexate for selected patients with recurrent disease. In the past decade, multiple new agents, high-dose chemotherapy, combinations, and intra-arterial approaches have been used for the patient with recurrent disease. Wheeler critically assesses the current status of these approaches. When oncologists began testing chemotherapy in the combined modality approach, trials consisted of induction chemotherapy and use of single agents as radiosensitizers. Although a great deal has been learned from these trials, benefit in terms of survival has been marginal. Even more promising may be the concomitant use of combination chemo therapy and radiation. Taylor describes the encouraging results as well as the potential. Induction chemotherapy may have a second important goal in addition to improving curability-it could be used for organ preservation. Dimery et al., present the background for this approach in the patient with laryngeal cancer as well as a description of their randomized trial for voice preservation. Head and neck squamous cancers are a heterogeneous group of diseases, and surgeons have long sought parameters that will help predict outcome.


Functional Preservation and Quality of Life in Head and Neck Radiotherapy

Functional Preservation and Quality of Life in Head and Neck Radiotherapy

Author: Paul M. Harari

Publisher: Springer Science & Business Media

Published: 2009-06-12

Total Pages: 323

ISBN-13: 3540732322

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The emphasis on cancer management in the past was based primarily on control rates from multidisciplinary input in management. There has always been a recognition that one would like to achieve the best result with the least complication, but never has there been any major emphasis on evidence-based outcome studies, nor on functional preservation and quality of life. The authors of this book have dealt very effectively with the various tumor types in head and neck cancer with the experts in the ? eld of management. The contents range from epidemiology and treatment outcome, treatment techniques with the potential impact on the quality of life such as dysphagia, to the various options relative to high technology radiation therapy programs for mana- ment. The potential for improving form and function through surgical care as an integrated part of the program is dealt with very effectively as well as the potentials for chemotherapy and the use of targeted agents have on quality of life issues. The volume also addresses toxicity, quality of life, and techniques for prevention of adverse effects, as well as the potentials for rehabilitation and supportive care. The authors have clearly done an extraordinarily good job in addressing the mul- plicity of problems that impact upon the functional preservation and quality of life in head and neck radiation therapy. Philadelphia Luther W.


Issues in Head and Neck Cancer

Issues in Head and Neck Cancer

Author: Rehan Kazi

Publisher: Byword Books Private Limited

Published: 2012-03-29

Total Pages: 164

ISBN-13: 8181930762

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Head and neck cancer (HNC) is a rapidly evolving field of medical science. Tremendous progress has been made over the past five decades in revealing the basic molecular biology involved in the disease process, developing and adopting more effective organ-preserving treatment protocols and refining surgical ablative and reconstructive approaches to facilitate functional restoration of patients without compromising survival. We now have a much clearer understanding of the disease, its management and the rehabilitation of patients. But there is still much to be done. This book aims to cover a range of exciting new findings in clinical sciences, basic sciences and allied specialties with an emphasis on their relevance to HNC. This work promises to improve preventive and therapeutic strategies and will hopefully culminate in improved outcomes of HNC. The contributions have been made by established leaders in the field and every effort has been made to address the issue in a comprehensive, yet concise, manner for the benefit of readers. We believe that this book will be of value to established/in-training clinicians, scientists, allied professionals, as well as medical students who have inquisitive minds and wish to further enhance their knowledge of HNC.


Head and Neck Cancer

Head and Neck Cancer

Author: Bruce Brockstein

Publisher: Springer Science & Business Media

Published: 2006-04-18

Total Pages: 380

ISBN-13: 0306480603

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Exciting advances are occurring in the understanding of the molecular pathogenesis of squamous head and neck cancers. Epidemiology, staging and screening, as well as premalignancy, chemoprevention and the molecular biology of head and neck cancer, lay the groundwork for the understanding of the clinical chapters that follow. Controversial treatments will be compared to the standard management of patient care. Therapy chapters are divided into stage or category specific (resectable advanced, unresectable advanced or metastatic) problems, allowing the reader to review the current standards and options for patient types or specific patients easily. Considerations of supportive care, late toxicities and quality of life, often overlooked are reviewed in detail. This is a comprehensive summary of the current state of the art research and treatment.


Functional Preservation and Quality of Life in Head and Neck Radiotherapy

Functional Preservation and Quality of Life in Head and Neck Radiotherapy

Author: Paul M. Harari

Publisher: Springer

Published: 2011-11-24

Total Pages: 329

ISBN-13: 9783540868040

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The emphasis on cancer management in the past was based primarily on control rates from multidisciplinary input in management. There has always been a recognition that one would like to achieve the best result with the least complication, but never has there been any major emphasis on evidence-based outcome studies, nor on functional preservation and quality of life. The authors of this book have dealt very effectively with the various tumor types in head and neck cancer with the experts in the ? eld of management. The contents range from epidemiology and treatment outcome, treatment techniques with the potential impact on the quality of life such as dysphagia, to the various options relative to high technology radiation therapy programs for mana- ment. The potential for improving form and function through surgical care as an integrated part of the program is dealt with very effectively as well as the potentials for chemotherapy and the use of targeted agents have on quality of life issues. The volume also addresses toxicity, quality of life, and techniques for prevention of adverse effects, as well as the potentials for rehabilitation and supportive care. The authors have clearly done an extraordinarily good job in addressing the mul- plicity of problems that impact upon the functional preservation and quality of life in head and neck radiation therapy. Philadelphia Luther W.


Head and Neck Cancer Recurrence

Head and Neck Cancer Recurrence

Author: Hisham M. Mehanna

Publisher: Thieme

Published: 2021-04-14

Total Pages: 716

ISBN-13: 3132579998

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Despite significant progress in the treatment of head and neck cancer using new techniques, including organ preservation strategies, recurrence still occurs in up to 50% of patients with locally advanced disease. Head and Neck Cancer Recurrence is the first comprehensive, evidence-based reference on this complex condition, providing state-of-the-art strategies for treating and managing recurrence at each site within the head and neck. With this book at hand, specialists will have guidelines for detecting the presence of a tumor, evaluating the extent and likelihood of successful salvage, determining the most effective treatment modalities, and assessing the potential impact on outcome and function. Special features: Brings together all the current evidence and expertise on the epidemiology, risk factors, clinical and imaging evaluation, and management of recurrent head and neck cancer tumors Includes both curative and palliative approaches, and discusses surgical, radiotherapeutic, and chemotherapeutic strategic options Contains substantial contributions by specialists in speech and language therapy, palliative care, psychology, epidemiology, and clinical cancer nursing to provide a holistic, multidisciplinary approach to the management of recurrence of head and neck cancers Brings the decision-making process to life with illustrative case studies that contain patient histories, clinical findings, treatment planning, and documented results The combination of the most recent clinical advances with the latest thinking in the field makes this book an essential resource for all head and neck surgeons, clinical oncologists, radiation oncologists, nurse practitioners, allied health professionals and senior trainees working to improve patient management and outcomes in this challenging arena.