TNFR Superfamily Oligomerization and Signaling
Author: Cristian Roberto Smulski
Publisher: Frontiers Media SA
Published: 2021-06-08
Total Pages: 132
ISBN-13: 2889668460
DOWNLOAD EBOOKRead and Download eBook Full
Author: Cristian Roberto Smulski
Publisher: Frontiers Media SA
Published: 2021-06-08
Total Pages: 132
ISBN-13: 2889668460
DOWNLOAD EBOOKAuthor: Harald Wajant
Publisher: Springer Science & Business Media
Published: 2007-04-03
Total Pages: 169
ISBN-13: 0387345736
DOWNLOAD EBOOKFas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph.D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule.
Author:
Publisher: Elsevier
Published: 2020-03-10
Total Pages: 228
ISBN-13: 044464217X
DOWNLOAD EBOOKInfections in Systemic Autoimmune Diseases: Risk Factors and Management, Volume Sixteen describes the state-of-the-art of the risk factors and management treating the most common systemic autoimmune diseases (SADS). This updated volume consists of an introductory chapter that provides a brief overview of what different types of infectious diseases exist, followed by eight chapters detailing risk factors, guidelines and recommendations per different disease and bacterial infections. International in scope, the list of more than 20 contributors from Europa and America reads like a who's who of clinical researchers in the field.
Author: Joseph A. Marsh
Publisher: Humana
Published: 2019-04-15
Total Pages: 506
ISBN-13: 9781493992775
DOWNLOAD EBOOKThis volume details the importance of multiple experimental techniques and computational methods needed to obtain the comprehensive picture of protein complex structure, dynamics and assembly afforded by the emerging field of integrative structural biology. Chapters guide readers through the broad spectrum of approaches required for a complete representation of protein complexes, including expression and purification, experimental characterization of structure and assembly, and computational methods for identifying protein complexes and modelling their assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Protein Complex Assembly: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Author: North Atlantic Treaty Organization. Scientific Affairs Division
Publisher: IOS Press
Published: 2001
Total Pages: 220
ISBN-13: 9781586030803
DOWNLOAD EBOOKThis volume contains 20 papers from two courses ("Methods for Macromolecular Crystallography" and "Chemical Prospective in Crystallography of Molecular Biology") held during the late spring of 2000 in Reice, Italy. The papers discuss crystals, synchrotrons, detector development, data processing, ab initio phasing and high and low resolution, molecular placement, experimental phase measurement, density modification methods, map improvements, interpretation of electron density maps, automatic structure determination, and the dissection of ultra-high resolution structures. c. Book News Inc.
Author: Gary R. Lewin
Publisher: Springer Science & Business Media
Published: 2014-03-25
Total Pages: 514
ISBN-13: 3642451063
DOWNLOAD EBOOKThis book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington’s syndrome, cognitive function, psychiatric disorders such as clinical depression, Rett syndrome, motoneurone disease, spinal cord injury, pain, metabolic disease and cardiovascular disease. It also contains contributions from leaders in the field dealing with the basic biology, transcriptional and post-translational regulation of the neurotrophins and their receptors. The present book will review all recent areas of progress in the study of neurotrophins and their biological roles.
Author: Philip J. Hashkes
Publisher: Springer
Published: 2019-02-13
Total Pages: 793
ISBN-13: 3319986058
DOWNLOAD EBOOKThis book, the first complete textbook on this novel field in Medicine, comprehensively covers the clinical presentation, pathogenesis, genetics, and latest management strategies for autoinflammatory disorders as well as the basic science of autoinflammation. Relevant concepts such as how translational science of genetics and immunology relates to the innate immune system and autoinflammation are covered. Descriptions of the monogenic and polygenic/complex diseases that fall under the umbrella of autoinflammatory diseases are provided. Further topics covered include the latest clinical and genetic diagnostic approaches, concepts on the relationship between autoinflammation and autoimmunity/immunodeficiency, the role of autoinflammation in cancer, treatments and management strategies for these diseases, and potential areas of future development. The Textbook of Autoinflammation systematically describes and reviews diagnostic and treatment options for autoinflammatory disorders as well as all aspects of the concept of autoinflammation, and represents a valuable resource for professionals in a variety of disciplines who encounter these patients or who study autoinflammation.
Author: Tamas Fulop
Publisher: Springer Science & Business Media
Published: 2009-02-27
Total Pages: 1693
ISBN-13: 1402090633
DOWNLOAD EBOOKThis authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.
Author: Sangdun Choi
Publisher: Springer
Published: 2012-07-09
Total Pages: 0
ISBN-13: 9781441904607
DOWNLOAD EBOOKBiological processes are driven by complex systems of functionally interacting signaling molecules. Thus, understanding signaling molecules is essential to explain normal or pathological biological phenomena. A large body of clinical and experimental data has been accumulated over these years, albeit in fragmented state. Hence, systems biological approaches concomitant with the understanding of each molecule are ideal to delineate signaling networks/pathways involved in the biologically important processes. The control of these signaling pathways will enrich our healthier life. Currently, there are more than 30,000 genes in human genome. However, not all the proteins encoded by these genes work equally in order to maintain homeostasis. Understanding the important signaling molecules as completely as possible will significantly improve our research-based teaching and scientific capabilities. This encyclopedia presents 350 biologically important signaling molecules and the content is built on the core concepts of their functions along with early findings written by some of the world’s foremost experts. The molecules are described by recognized leaders in each molecule. The interactions of these single molecules in signal transduction networks will also be explored. This encyclopedia marks a new era in overview of current cellular signaling molecules for the specialist and the interested non-specialist alike During past years, there were multiple databases to gather this information briefly and very partially. Amidst the excitement of these findings, one of the great scientific tasks of the coming century is to bring all the useful information into a place. Such an approach is arduous but at the end will infuse the lacunas and considerably be a streamline in the understanding of vibrant signaling networks. Based on this easy-approach, we can build up more complicated biological systems.
Author: Gerhard Krauss
Publisher: John Wiley & Sons
Published: 2006-03-06
Total Pages: 558
ISBN-13: 3527605762
DOWNLOAD EBOOKThis all-new edition of a classic text has been thoroughly revised to keep pace with the rapid progress in signal transduction research. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes. Directed to advanced students, teachers, and researchers in biochemistry and molecular biology, this book describes the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis. "Provides a comprehensive account of cell signaling and signal transduction and, where possible, explains these processes at the molecular level" (Angewandte Chemie) "The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry) "This book is actually two books: Regulation and Signal Transduction." (Drug Research)