Children and Drug Safety

Children and Drug Safety

Author: Cynthia A Connolly

Publisher: Rutgers University Press

Published: 2018-05-11

Total Pages: 328

ISBN-13: 0813575230

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Winner of the 2018 Arthur J. Viseltear Award from the Medical Care Section of the American Public Health Association​ Children and Drug Safety traces the development, use, and marketing of drugs for children in the twentieth century, a history that sits at the interface of the state, business, health care providers, parents, and children. This book illuminates the historical dimension of a clinical and policy issue with great contemporary significance—many of the drugs administered to children today have never been tested for safety and efficacy in the pediatric population. Each chapter of Children and Drug Safety engages with major turning points in pediatric drug development; themes of children’s risk, rights, protection and the evolving context of childhood; child-rearing; and family life in ways freighted with nuances of race, class, and gender. Cynthia A. Connolly charts the numerous attempts by Congress, the Food and Drug Administration, the American Academy of Pediatrics, and leading pediatric pharmacologists, scientists, clinicians, and parents to address a situation that all found untenable. Open access edition funded by the National Endowment for the Humanities. The text of this book is licensed under a Creative Commons Attribution NonCommercial-NoDerivatives 4.0 International License: https://creativecommons.org/licenses/by-nc-nd/4.0/


Aspirin

Aspirin

Author: Diarmuid Jeffreys

Publisher: Chemical Heritage Foundation

Published: 2008-12

Total Pages: 352

ISBN-13: 1596918160

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A fast-paced, medical-historical mystery, filled with twists and turns.-Chicago Tribune


The Renaissance of Aspirin

The Renaissance of Aspirin

Author: Glenn Parris

Publisher: Xlibris Corporation

Published: 2013-05-16

Total Pages: 404

ISBN-13: 1483633012

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This is the story of Anita Thomas and Jack Wheaton, two young doctors unwittingly in possession of a designer antibody for the treatment of fibromyalgia syndrome. The new drug is effective, but dangerously flawed. The problem is Anita Thomas has developed a cheap, safe alternative agent. Naturally, after expenditure of a fortune in development, the drug manufactures are not at all pleased with her. The pieces unfold, as we follow Anita and Jack from beautiful upscale midtown to the seedier downtown counterparts of Boston and Atlanta over shadowed by deadly stalkers and embellished by amorous often comically frustrating misadventures. The Renaissance of Aspirin is peppered with industrial espionage, suspense and passion as the chase is on for the first cure for fibromyalgia. Entangled with colorful comrades such as Dasher Clay; Stormi Seales and Khandi Barr in their camp, Anita and Jack barely keep ahead of the treacherous cabal of nemeses; Luciana Velasquez and Jason Brasil led by the Über-villain, Orson Quirk. Paced in the tradition of The Pelican Brief, Coma or a contemporary Maltese Falcon, The Renaissance of Aspirin is both plot and character driven with a ly credible McGuffin at its core. These complex characters are funny, mean, desperate, lonely and at the same time very humanly imperfect. Readers will find their prickly exploits thoroughly entertaining.


Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

Author: Agency for Health Care Research and Quality (U.S.)

Publisher: Government Printing Office

Published: 2013-02-21

Total Pages: 236

ISBN-13: 1587634236

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This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)


Microscale Chemistry

Microscale Chemistry

Author: John Skinner

Publisher: Royal Society of Chemistry

Published: 1997

Total Pages: 216

ISBN-13: 1870343492

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Developing microscale chemistry experiments, using small quantities of chemicals and simple equipment, has been a recent initiative in the UK. Microscale chemistry experiments have several advantages over conventional experiments: They use small quantities of chemicals and simple equipment which reduces costs; The disposal of chemicals is easier due to the small quantities; Safety hazards are often reduced and many experiments can be done quickly; Using plastic apparatus means glassware breakages are minimised; Practical work is possible outside a laboratory. Microscale Chemistry is a book of such experiments designed for use in schools and colleges, and the ideas behind the experiments in it come from many sources, including chemistry teachers from all around the world. Current trends indicate that with the likelihood of further environmental legislation, the need for microscale chemistry teaching techniques and experiments is likely to grow. This book should serve as a guide in this process.


The Lupus Book

The Lupus Book

Author: Daniel J. Wallace

Publisher: Oxford University Press, USA

Published: 2013

Total Pages: 303

ISBN-13: 0199929408

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Lupus, a disease of the immune system, can be quite deadly, claiming the lives of thousands of patients yearly. Dr. Daniel J. Wallace is one of the world's leading authorities on this disorder, an eminent clinician who has treated over 3000 lupus patients, the largest such practice in America. His The Lupus Book, originally published in 1995, immediately established itself as the most readable and helpful book on the disease. Now Dr. Wallace has once again completely revised The Lupus Book, incorporating a wealth of new information. This Fifth Edition discusses new drug information and newly discovered information about the pathology of the disease--all laid out in user-friendly language that any patient could understand. In particular, Wallace discusses the first drug for Lupus to be approved by the FDA--belimumab (Benlysta)--as well as other drugs in clinical trials. Readers will also discover fully updated sections on the science of lupus and breakthroughs in research. And as in past editions, the book provides absolutely lucid answers to such questions as: What causes lupus? How and where is the body affected? Can a woman with lupus have a baby? And how can one manage this disease? Indeed, Dr. Wallace has distilled his extensive experience, providing the most up-to-date information on causes, prevention, cure, exercise, diet, and many other important topics. There is also a glossary of terms and an appendix of lupus resource materials compiled by the Lupus Foundation of America. Over a million Americans have lupus. The new Fifth Edition offers these patients and their families an abundance of reliable, up-to-date information that will help them manage the disease and live a happier life.


Acute Stroke Nursing

Acute Stroke Nursing

Author: Jane Williams

Publisher: John Wiley & Sons

Published: 2013-05-07

Total Pages: 367

ISBN-13: 1118699629

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Stroke is a medical emergency that requires immediate medical attention. With active and efficient nursing management in the initial hours after stroke onset and throughout subsequent care, effective recovery and rehabilitation is increased. Acute Stroke Nursing provides an evidence-based, practical text facilitating the provision of optimal stroke care during the primary prevention, acute and continuing care phases. This timely and comprehensive text is structured to follow the acute stroke pathway experienced by patients. It explores the causes, symptoms and effects of stroke, and provides guidance on issues such as nutrition, continence, positioning, mobility and carer support. The text also considers rehabilitation, discharge planning, palliative care and the role of the nurse within the multi-professional team. Acute Stroke Nursing is the definitive reference on acute stroke for all nurses and healthcare professionals wishing to extend their knowledge of stroke nursing. Evidence-based and practical in style, with case studies and practice examples throughout Edited and authored by recognised stroke nursing experts, clinicians and leaders in the field of nursing practice, research and education The first text to explore stroke management from UK and international perspectives, and with a nursing focus


Ending Medical Reversal

Ending Medical Reversal

Author: Vinayak K. Prasad

Publisher: Johns Hopkins University Press

Published: 2019-05-14

Total Pages: 276

ISBN-13: 1421429047

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Why medicine adopts ineffective or harmful medical practices only to abandon them—sometimes too late. Medications such as Vioxx and procedures such as vertebroplasty for back pain are among the medical "advances" that turned out to be dangerous or useless. What Dr. Vinayak K. Prasad and Dr. Adam S. Cifu call medical reversal happens when doctors start using a medication, procedure, or diagnostic tool without a robust evidence base—and then stop using it when it is found not to help, or even to harm, patients. In Ending Medical Reversal, Drs. Prasad and Cifu narrate fascinating stories from every corner of medicine to explore why medical reversals occur, how they are harmful, and what can be done to avoid them. They explore the difference between medical innovations that improve care and those that only appear to be promising. They also outline a comprehensive plan to reform medical education, research funding and protocols, and the process for approving new drugs that will ensure that more of what gets done in doctors' offices and hospitals is truly effective.


Applied Pharmacology

Applied Pharmacology

Author: Stan K. Bardal

Publisher: Elsevier Health Sciences

Published: 2011-01-01

Total Pages: 482

ISBN-13: 1437703100

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Applied Pharmacology provides the essential details that are required for a solid understanding of pharmacology: how the drugs work, why side effects occur, and how the drugs are used clinically. Drs. Stan Bardal, Jason Waechter, and Doug Martin integrate the experience of the pharmacologist and the physician for a clinical focus that ensures a complete understanding of pharmacology.in print and online. Find information quickly and compare and contrast drugs easily thanks to a clear and consistent format without extraneous material. Apply basic pharmacology to clinical situations through integrated text. Enhance your learning with "For Your Information" sections detailing history and anecdotes for many agents within a given drug class. Access the fully searchable text online at studentconsult.com, along with 150 USMLE-style multiple choice questions, downloadable images, and online only references. Learn the essential details of pharmacology and enhance your understanding through an entirely new, fantastic art program. Gain a thorough understanding of key pharmacology components in a concise and efficient format


Acetylsalicylic Acid

Acetylsalicylic Acid

Author: Karsten Schrör

Publisher: John Wiley & Sons

Published: 2016-09-26

Total Pages: 474

ISBN-13: 3527338055

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Written by a leading expert on Aspirin-related research, this is the most comprehensive treatise on the pharmacological effects and clinical applications of one of the most successful drugs ever. The text is written with a wide audience in mind, and to be readily understandable for clinicians, pharmacists, biomedical researchers and pharmacologists alike. This second, completely revised edition contains the latest results of clinical and pharmacological research on Acetylsalicylic acid, addressing the multiple pharmacological properties of this famous drug with a balanced view on their translation into clinical practice, including prevention from cardiovascular diseases and colorectal cancer.