Handbook of Nanomaterials for Cancer Theranostics

Handbook of Nanomaterials for Cancer Theranostics

Author: Joao Conde

Publisher: Elsevier

Published: 2018-06-27

Total Pages: 608

ISBN-13: 0128133406

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Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. - Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics - Explores the regulatory hurdles facing theranostic nanomedicine - Discusses how the use of nanomaterials can help create more effective cancer treatments


Design of Nanostructures for Theranostics Applications

Design of Nanostructures for Theranostics Applications

Author: Alexandru Mihai Grumezescu

Publisher: William Andrew

Published: 2017-11-30

Total Pages: 695

ISBN-13: 0128136707

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Design of Nanostructures for Theranostics Applications focuses on the theranostics applications of nanostructures. In particular, multifunctional nanoparticles for diagnostics and treatment of different diseases, including those relating to the blood-brain barrier, are discussed in detail. Chapters explore different type of nanostructures, covering design, fabrication, functionalization and optimization, helping readers obtain the desired properties. Written by a diverse range of international academics, this book is a valuable reference resource for those working in both nanoscience and the pharmaceutical industry. - Explores how the design of a range of nanomaterials make them effective theranostic agents, including multifunctional core-shell nanostructures, mesoporous silica nanoparticles, and quantum dots - Shows how nanomaterials are used effectively for a range of diseases, including breast cancer, prostate cancer and neurological disorders - Assesses the pros and cons of using different nanomaterials for different types of treatment


Multifunctional Theranostic Nanomedicines in Cancer

Multifunctional Theranostic Nanomedicines in Cancer

Author: Malay K. Das

Publisher: Academic Press

Published: 2021-03-16

Total Pages: 428

ISBN-13: 0128217006

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Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. - Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines - Discusses treatment options from a pharmaceutical sciences perspective - Includes translational science and targeted CNS cancer treatment


Functionalized Carbon Nanomaterials for Theranostic Applications

Functionalized Carbon Nanomaterials for Theranostic Applications

Author: Shadpour Mallakpour

Publisher: Elsevier

Published: 2022-09-17

Total Pages: 588

ISBN-13: 0128243678

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Functionalized Carbon Nanomaterials for Theranostic Applications offers insights into the developments and trends that are progressing fast in the field of functionalized carbon nanomaterials-based devices as diagnostic tools for early stage detection of human diseases. The book provides information on how functionalized carbon nanomaterials are being used as the basis for products, such as early disease diagnostic kits, quantum dots for medical imaging and a growing list of other applications. Sections cover different mechanical, absorption, optical and electrical properties than those found in original nanomaterials. This is an important reference source that will be valuable to materials scientists, biomedical engineers and pharmaceutical scientists who are looking to increase their understanding on how functionalized carbon nanomaterials are being used for a variety of theranostic applications. - Provides readers with information on how to develop functionalized carbon nanomaterials based diagnostic devices and tools - Identifies fabrication and characterization methods for integrated devices for use in theranostic applications - Assesses major challenges for manufacturing functionalized carbon nanomaterial materials for theranostic devices on an industrial scale


Nano-Pharmacokinetics and Theranostics

Nano-Pharmacokinetics and Theranostics

Author: Nanasaheb D. Thorat

Publisher: Elsevier

Published: 2021-07-30

Total Pages: 324

ISBN-13: 0323850502

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Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy addresses from a comprehensive and multidisciplinary approach the translational aspects and clinical perspectives of nano-pharmacokinetics using cancer as a model disease. Nano-pharmacokinetics is emerging as an important sub discipline of nanoscience and medical sciences because of the increasing safety issues of nanosystems on living organisms. This book reports the dynamics of nanosystems in living organisms for better understanding of nanotoxicity, pharmacology, biochemistry, physiology and medicine perspectives. It further examines current progress of state-of-the art pharmacokinetics mechanisms, which will be of great help to develop more clinical-oriented nanosystems with a wide safety margin. The book is divided into three sections: the first section focuses on the concept of pharmacokinetics with state-of-the-art Nano-Pharmacokinetics (NPK). The second section looks at the engineering of nanoparticles and pharmacokinetics clinical development. The final section focuses on Nano-Pharmacokinetics and Theranostics, elaborating the basic question of how pharmacokinetics of nanomaterials relate to their end applications such as cancer therapy. Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy will be useful to researchers in the field of nanoparticle based targeted drug delivery including pharmaceutical scientists, material scientists, chemists, nanotechnologists, biomedical scientists, and clinicians. Includes contributions from highly qualified scientists, regulatory entities, enterprises and medical practitioners to explain the long and inherently multidisciplinary pathway of nano-pharmacokinetics Describes assessment methods of nano-pharmacokinetics Examines the interface between nanomedicine and pharmacokinetics to diagnose and treat cancer


Theranostics Nanomaterials in Drug Delivery

Theranostics Nanomaterials in Drug Delivery

Author: Prashant Kesharwani

Publisher: Elsevier

Published: 2024-10-10

Total Pages: 896

ISBN-13: 044322045X

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Theranostics Nanomaterials in Drug Delivery presents the most recent advances in the development of theranostic nanomaterials for drug delivery. This book compiles reports and studies on the latest changes and improvements of theranostic nanocarriers such as nanoemulsions, liposomes, exosomes, polymeric micelles, PLGA nanoparticles, chitosan nanoparticles, dendrimer, quantum dots, silica nanoparticles, gold nanoparticles, silver nanoparticles, magnetic nanoparticles, and many more, all of which can help in the sensitive diagnosis, precise targeting, and efficient and controlled delivery of nanomaterials to control various diseases at different clinical stages. Theranostics nanomaterials in drug delivery will serve as a solid foundation and reference for pharmaceutical scientists, undergraduate and postgraduate students, researchers, and experts in the medical field involved in the development of advanced drug delivery systems. - Presents a compilation of thoroughly analyzed data and results regarding the usage of theranostics nanocarriers as a platform for diagnosis and treatment of various diseases - Gathers novel drug delivery applications of theranostics nanocarriers in biological milieu and discusses the principles behind the formation, characterization, applications, and future perspectives of theranostics for targeted therapy development - Discusses the most recent technologies in theranostics nanometrials to help readers define major gaps in knowledge that can lead new scientific breakthroughs and discoveries


Cancer Nanotheranostics

Cancer Nanotheranostics

Author: Muthupandian Saravanan

Publisher: Springer Nature

Published: 2021-10-05

Total Pages: 362

ISBN-13: 3030743306

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Nanotechnology is an interdisciplinary research field that integrates chemistry, engineering, biology, and medicine. Nanomaterials offer tremendous opportunity as well as challenges for researchers. Of course, cancer is one of the world's most common health problems, responsible for many deaths. Exploring efficient anticancer drugs could revolutionize treatment options and help manage cancer mortality. Nanomedicine plays a significant role in developing alternative and more effective treatment strategies for cancer theranostics. This book mainly focuses on the emerging trends using nanomaterials and nanocomposites as alternative anticancer material’s. The book is divided into three main topic areas: how to overcome existing traditional approaches to combat cancer, applying multiple mechanisms to target the cancer cells, and how nanomaterials can be used as effective carriers. The contents highlight recent advances in interdisciplinary research on processing, morphology, structure, and properties of nanostructured materials and their applications to combat cancer.Cancer Nanotheranostics is comprehensive in that it discusses all aspects of cancer nanotechnology. Because of the vast amount of information, it was decided to split this material into two volumes. In the first volume of Cancer Nanotheranostics, we discuss the role of different nanomaterials for cancer therapy, including lipid-based nanomaterials, protein and peptide-based nanomaterials, polymer-based nanomaterials, metal-organic nanomaterials, porphyrin-based nanomaterials, metal-based nanomaterials, silica-based nanomaterials, exosome-based nanomaterials and nano-antibodies. In the second volume, we discuss the nano-based diagnosis of cancer, nano-oncology for clinical applications, nano-immunotherapy, nano-based photothermal cancer therapy, nano-erythrosomes for cancer drug delivery, regulatory perspectives of nanomaterials, limitations of cancer nanotheranostics, the safety of nano-biomaterials for cancer nanotheranostics, multifunctional nanomaterials for targeting cancer nanotheranostics, and the role of artificial intelligence in cancer nanotheranostics.


Nano Medicine and Nano Safety

Nano Medicine and Nano Safety

Author: Malay K. Das

Publisher: Springer Nature

Published: 2020-12-09

Total Pages: 634

ISBN-13: 9811562555

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This book reviews the application of Nanobiotechnology in the development of Nanomedicine, while also discussing the latest trends and challenges in the clinical translation of Nanomedicine. Nanomedicine refers to the application of Nanotechnology to medicine and holds tremendous potential for achieving improved efficiency, bioavailability, dose response, personalized medicine and enhanced safety as compared to conventional medicines. The book first introduces readers to the basic concepts of Nanomedicine, and to technological advances in and applications of Nanotechnology in treatment, diagnosis, monitoring, and drug delivery. In turn, it reviews the current status of multi-functionalization strategies for using Nanoparticles in the targeted delivery of therapeutic agents. The book’s third and final section focuses on the regulatory and safety challenges posed by Nanomedicine, including industry and regulatory agencies’ efforts to address them.


Theranostics Approaches to Gastric and Colon Cancer

Theranostics Approaches to Gastric and Colon Cancer

Author: Ganji Seeta Rama Raju

Publisher: Springer Nature

Published: 2020-03-04

Total Pages: 261

ISBN-13: 9811520178

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This book highlights the importance of understanding gastric and colon cancer metabolism in guiding diagnosis and drug discovery. It summarizes the correlation between adiponectin and matrix metalloproteinase with colorectal cancer. The book also evaluates the divergent role of hypoxia-inducible factor 1 in colorectal cancer growth and metastasis. After discussing the role of genetic polymorphisms in alcohol metabolizing enzymes and EPHX1 with the onset of colorectal cancer, it reviews the molecular mechanisms of chemoresistance in gastric cancer and novel therapeutic strategies to reverse the chemoresistance of tumors. In addition, the book explores the theranostic role of nanoparticles and therapeutic potential of phytochemicals with regard to colorectal cancer. Given its scope, the book offers a valuable guide for oncologists, academic researchers, pharmaceuticals practitioners, and students who are involved in research and treatment of cancer.


Particles and Nanoparticles in Pharmaceutical Products

Particles and Nanoparticles in Pharmaceutical Products

Author: Henk G. Merkus

Publisher: Springer

Published: 2018-09-06

Total Pages: 455

ISBN-13: 3319941747

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This edited volume brings together the expertise of numerous specialists on the topic of particles – their physical, chemical, pharmacological and toxicological characteristics – when they are a component of pharmaceutical products and formulations. The book discusses in detail properties such as the composition, size, shape, surface properties and porosity of particles with respect to how they impact the formulations and products in which they are used and the effective delivery of pharmaceutical active ingredients. It considers all dosage forms of pharmaceuticals involving particles, from powders to tablets, creams to ointments, and solutions to dry-powder inhalers, also including the latest nanomedicine products. Further, it discusses examples of particle toxicity, as well as the important subject of pharmaceutical industry regulations, guidelines and legislation. The book is of interest to researchers and practitioners who work on testing and developing pharmaceutical dosage and delivery systems.