Inorganic Nanoprobes for Biological Sensing and Imaging

Inorganic Nanoprobes for Biological Sensing and Imaging

Author: Hedi Mattoussi

Publisher: Artech House

Published: 2009

Total Pages: 332

ISBN-13: 1596931973

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This groundbreaking resource offers you an up-to-date account of the pioneering activity pushing new boundaries in the emerging area of inorganic nanoprobes and their use in biology and medicine. Written and edited by leading experts in the field, this unique book places particular emphasis nanoprobes made of luminescent semiconductor nanocrystals (quantum dots or QDs) and magnetic nanoparticles (MNPs). You find an insightful discussion on the synthesis, characterization, and analysis of the unique properties of luminescent QDs and MNPs.


Photoactive Inorganic Nanoparticles

Photoactive Inorganic Nanoparticles

Author: Julia Pérez Prieto

Publisher: Elsevier

Published: 2019-03-09

Total Pages: 284

ISBN-13: 0128145323

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Nanoparticles are usually designed for specific applications and selection of the most convenient capping can be a complex task, but is crucial for successful design. In this volume, the authors discuss the selection of functional cappings to coat nanoparticles in a range of different applications. The opening chapter provides an understanding of basic aspects of surface chemistry at the nanoscale. Each following chapter covers a particular kind of capping, beginning with a basic introduction and describing characteristics such as structure, functionality, solubility, (photo)physics, and toxicity. Special emphasis is placed on how important these specific features are in the preparation of smart nanomaterials. In-depth explanations and examples are then presented, highlighting the latest results and cutting-edge research carried out with the selected capping according to the kind of nanoparticle employed (such as rare-earth doped, semiconducting, and metallic). An additional chapter focusses on computational techniques for modelling nanosurfaces. Photoactive Inorganic Nanoparticles: Surface Composition and its Role in Nanosystem Functionality will be a valuable working resource for graduate students, researchers, and industry R&D professionals working in the field of applied nanomaterials. Aids selection of the best functional cappings for particular applications Covers a broad range of application areas, including medical, biological and materials science Provides material on computational techniques for modeling nanosurfaces


Sensing and Biosensing with Optically Active Nanomaterials

Sensing and Biosensing with Optically Active Nanomaterials

Author: Suban K. Sahoo

Publisher: Elsevier

Published: 2021-10-21

Total Pages: 596

ISBN-13: 0323902456

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Sensing and Biosensing with Optically Active Nanomaterials summarizes the potential sensing applications of optically (chromogenic and fluorogenic) active, nano-sized, organic, and inorganic materials for the selective detection of ionic analytes (such as metal ions and anions) in various environmental and biological samples. Sections cover design, synthesis, sensing mechanisms and applications for detecting ionic analytes. Each chapter deals with the sensing applications of one kind of nanomaterial. This book is an important reference source for materials scientists and engineers seeking to increase their understanding on how nanomaterials are being used for sensing applications. Provides information on the various types of optically active inorganic and organic nanomaterials, including quantum dots, SPR active noble metal nanoparticles, metal nanoclusters, organic nanoparticles and carbon dots Summarizes the synthesis, design and development of sensors, along with their mechanisms Explains major sensing applications and manufacturing challenges


Inorganic Nanoparticles

Inorganic Nanoparticles

Author: Claudia Altavilla

Publisher: CRC Press

Published: 2017-12-19

Total Pages: 885

ISBN-13: 1351833960

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Among the various nanomaterials, inorganic nanoparticles are extremely important in modern technologies. They can be easily and cheaply synthesized and mass produced, and for this reason, they can also be more readily integrated into applications. Inorganic Nanoparticles: Synthesis, Applications, and Perspectives presents an overview of these special materials and explores the myriad ways in which they are used. It addresses a wide range of topics, including: Application of nanoparticles in magnetic storage media Use of metal and oxide nanoparticles to improve performance of oxide thin films as conducting media in commercial gas and vapor sensors Advances in semiconductors for light-emitting devices and other areas related to the energy sector, such as solar energy and energy storage devices (fuel cells, rechargeable batteries, etc.) The expanding role of nanosized particles in the field of catalysis, art conservation, and biomedicine The book’s contributors address the growing global interest in the application of inorganic nanoparticles in various technological sectors. Discussing advances in materials, device fabrication, and large-scale production—all of which are urgently required to reduce global energy demands—they cover innovations in areas such as solid-state lighting, detailing how it still offers higher efficiency but higher costs, compared to conventional lighting. They also address the impact of nanotechnology in the biomedical field, focusing on topics such as quantum dots for bioimaging, nanoparticle-based cancer therapy, drug delivery, antibacterial agents, and more. Fills the informational gap on the wide range of applications for inorganic nanoparticles in areas including biomedicine, electronics, storage media, conservation of cultural heritage, optics, textiles, and cosmetics Assembling work from an array of experts at the top of their respective fields, this book delivers a useful analysis of the vast scope of existing and potential applications for inorganic nanoparticles. Versatile as either a professional research resource or textbook, this effective tool elucidates fundamentals and current advances associated with design, characterization, and application development of this promising and ever-evolving device.


Nanoscience in Dermatology

Nanoscience in Dermatology

Author: Michael R. Hamblin

Publisher: Academic Press

Published: 2016-08-13

Total Pages: 404

ISBN-13: 0128029455

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Nanoscience in Dermatology covers one of the two fastest growing areas within dermatological science, nanoscience and nanotechnology in dermatology. Recently, great progress has been made in the research and development of nanotechnologies and nanomaterials related to various applications in medicine and, in general, the life sciences. There is increasing enthusiasm for nanotechnology applications in dermatology (drug delivery, diagnostics, therapeutics, imaging, sensors, etc.) for understanding skin biology, improving early detection and treatment of skin diseases, and in the design and optimization of cosmetics. Light sensitive nanoparticles have recently been explored, opening a new era for the combined applications of light with nanotechnology, also called photonanodermatology. However, concerns have been raised regarding the adverse effects of intentional and unintentional nanoparticle exposure and their toxicity. Written by experts working in these exciting fields, this book extensively covers nanotechnology applications, together with the fundamentals and toxicity aspects. It not only addresses current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing scientists and dermatologists with a clear understanding of the advantages and challenges of nanotechnology in skin medicine. Provides knowledge of current and future applications of nanoscience and nanotechnology in dermatology Outlines the fundamentals, methods, toxicity aspects, and other relevant aspects for nanotechnology based applications in dermatology Coherently structured book written by experts working in the fields covered


Integrated Nanomaterials and their Applications

Integrated Nanomaterials and their Applications

Author: Deepa Suhag

Publisher: Springer Nature

Published: 2023-12-06

Total Pages: 496

ISBN-13: 981996105X

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The book provides an overview of different nanoparticles, their classification, and their applications in healthcare, food sciences, environmental sciences, and agricultural sciences. The introductory chapters discuss different types of nanoparticles, their types, and their structural properties. The subsequent chapter examines factors that influence the biocompatibility and toxicity of NPs for the safe and sustainable development of emerging nanoparticles. The chapter systematically reviews the nanoparticle-based contrast agents employed in most common biomedical imaging modalities. The book further examines the applications of advanced nanoparticle design that are utilized for both non-personalized and precision applications for improving precision therapies. The book provides a comprehensive update on nanoparticles’ toxic effects, the factors underlying their toxicity, and the mechanisms by which toxicity is induced. This book is an ideal guide for researchers and students interested in understanding the applications of nanoparticles in biomedical sciences and the healthcare sector.


Synthesis and Characterisation of Novel Inorganic Nanoparticles for Diagnostic and Therapeutic Applications

Synthesis and Characterisation of Novel Inorganic Nanoparticles for Diagnostic and Therapeutic Applications

Author: Vindya S Perera

Publisher:

Published: 2014

Total Pages: 162

ISBN-13:

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Recently, much attention has been given to the development of biomedical applications of nanotechnology which known as nanomedicine. Nanomedicine utilizes nanoparticles such as liposomes, polymeric nanoparticles, carbon nanotubes, nanowires, quantum dots and inorganic nanoparticles to diagnose and treat various diseases. This dissertation research has focused on the development of inorganic nanoparticles for diagnostic and therapeutic applications. Targeted nanoparticulate magnetic resonance imaging (MRI) contrast agents discussed in chapter 3 showed high MRI signal and will be invaluable for future tissue specific imaging and investigation of molecular and cellular events. Specifically, this study highlights that simple one-step method for preparing extremely stable and biocompatible NPs of the gadolinium ferrocyanide coordination polymer. These NPs exhibit no cytotoxicity. Furthermore, we have demonstrated that such NPs possess extremely high T1-weighted relaxivity, suggesting the potential of this coordination-polymer structural platform in the development of new-generation T1-weighted cellular MR probes for biological receptors or markers within the cell to study molecular events as well as for in vivo MR imaging in biomedical research and clinical applications. In chapter 4 synthesis and characterization of nanoparticulate contrast agent for X-ray computed tomography is reported. These nanoparticles offer a much higher contrast efficacy compared to clinical iodinated agents at 120 kVp. Together with long circulation time and low toxicity, these nanoparticles can act as a high-performance CT contrast agent for in vivo applications. The remaining chapters of this dissertation concern the synthesis of therapeutic nanoparticles. The first part of the chapter 5 describes the synthesis and characterization of Au@ZnMoS4 nanoparticles as copper depleting agent for the treatment of Wilson's disease. Their utility as copper depleting agent has been clearly demonstrated in vitro. In the second part of Chapter 5, the synthesis and characterization of therapeutic nanoparticles for angiogenesis inhibition is reported. In this dissertation project, anti-angiogenic function and mechanism of ZnMoS4 NPs in primary HUVECs was investigated in detail.